Protein Alignment Oatp58Db and Slco1a5

DIOPT Version :9

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_110465.1
• Gene: Slco1a5 / 80900
• RGDID: 70985
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 655
• Identity: 162/655 - (24%)
• Similarity: 286/655 - (43%)
• Gaps: 92/655 - (14%)

  Fly    21 VADDEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNI 85
            :.:.|||:.:.:..|            |:...||::....|....:::..|....:|.:|::|:|
  Rat     1 MGETEKRVATHEVRC------------FSKIKMFLLALTWAYVSKSLSGIYMNTMLTQIERQFDI 53

  Fly    86 PTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALR 150
            ||.|.|.|....:|..:....|:||:.::.|||..:.:|.:|:.:.|.||..||...|
  Rat    54 PTSIVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCVIMGLGCFLMSLPHFLMG------- 111

  Fly   151 LTEEYGMSESFGASLNITEKNDSLCHEKNSNCLERAGDYTPIV-----LFFIAQFIG----GIGC 206
               .|....:...:.|:: .|..||.|..|..|:...|....:     |.:|...:|    |||.
  Rat   112 ---RYEYETTISPTSNLS-SNSFLCMENRSQTLKPTQDPAECIKEMKSLMWIYVLVGNIIRGIGE 172

  Fly   207 SLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDP----FKKPLITTN 267
            :.....|:||::|.:.|..:|..:......::.||.:|..:.|.|..:|:|.    .....||..
  Rat   173 TPIMPLGISYIEDFAKSENSPLYIGILETGKVFGPIVGLLLGSFCASIYVDTGSVNTDDLTITPT 237

  Fly   268 DPRWMGAWWIGWILLTFILTISAVFVGMFPKEMP--------------RAKARRLKADGEEDIPL 318
            |.||:||||||:::...:..:|::....|||.:|              :.:..|.||. ||:..:
  Rat   238 DTRWVGAWWIGFLICAGVNILSSIPFFFFPKTLPKEGLQDDVDGTNNDKEEKHREKAK-EENRGI 301

  Fly   319 AGRSFQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWA 383
            .    :|.|..:|.|:.|.:|:..:|.|:|.:..::..:.|.|||:|.||.:|.:...:..|.:.
  Rat   302 T----KDFLPFMKSLSCNPIYMLLILTSVLQINAFINMFTFLPKYLEQQYGKSTAEVVLLIGVYN 362

  Fly   384 LGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGCDESDRANSLSIVPTG-- 446
            |.....|.|:.|:::.|:|.:.:..|...|.:..........:.::.||....| .|:....|
  Rat   363 LPPICIGYLLIGFIMKKFKITVKKAAYMAFCLSLFEYLLYFLHFMITCDNFPVA-GLTASYEGVH 426

  Fly   447 ----------DSCSASCVCEYVYYAPVCSPENITFISACHAGCTDKAINELGKTIYTGCRCM--- 498
                      ..|:..|.|....:.|||....:.::|||.||| .|::......::..|.|:
  Rat   427 HPLYVENKVLADCNRGCSCSTNSWDPVCGDNGLAYMSACLAGC-KKSVGTGTNMVFQNCSCIRSS 490

  Fly   499 GNVSSIISLSNVTSLASQSQIAMDGACP--VDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRC 561
            ||.|:::                 |.|.  .:|..:...||.:.....|:.:.......::.|||
  Rat   491 GNSSAVL-----------------GLCKKGPECANKLQYFLIMSVIGSFIYSITAIPGYMVLLRC 538

  Fly   562 VPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWGK-TCSSKGNCWIYDTKSLRYTMNL 625
            :..::|:..:|..:....|.|.||:||.||.::|..||.||. .|...|.|.:|:..:.|....:
  Rat   539 IKPEEKSLGIGLHAFCTRVFAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYNINNFRRIYLV 603

  Fly   626 VCASL 630
            :.|:|
  Rat   604 LPAAL 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	154/610 (25%)
		MFS	55..>410	CDD:119392	99/381 (26%)
		KAZAL_SLC21	447..499	CDD:238650	15/54 (28%)
Slco1a5	NP_110465.1	oat	1..625	CDD:273279	162/655 (25%)
		MFS	21..>397	CDD:119392	103/391 (26%)
		KAZAL_SLC21	436..487	CDD:238650	14/51 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920