Protein Alignment Oatp58Db and slco2b1

DIOPT Version :9

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001032767.2
• Gene: slco2b1 / 792084
• ZFINID: ZDB-GENE-051023-6
• Length: 677
• Species: Danio rerio
• Alignment Length: 636
• Identity: 173/636 - (27%)
• Similarity: 300/636 - (47%)
• Gaps: 90/636 - (14%)

  Fly    48 FATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYA 112
            |.....||:.:|:......:...|...:|||:|||:...:..|||:...|::.......|:|::.
Zfish    22 FNNIKFFVLCHGMLQLSQLLVSGYLKASITTIEKRYGFSSSKSGLLAAFNEVGNTVLIVFVSFFG 86

  Fly   113 SRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSESFGASLNITEKNDSLCH- 176
            ||.||||.:.:|.:|.::...|:..||.          ::|:|..:|    .::.|..|.|||.
Zfish    87 SRVHRPRCIGIGGMIASMGVFLIALPHF----------ISEKYEYTE----FISNTRLNSSLCQT 137

  Fly   177 ---EKNSNCLE-----RAGDYTPIVLFFIAQFIGGIGCSLFYAPGLSYMDDNSASSKTPAMLSWS 233
               |.:..|.:     :.|.| ||:|  :.|.:.|||.......|:||:||.:....:|..|...
Zfish   138 QDIESSPTCSQNDTDPQLGVY-PILL--LGQLLLGIGGVPIQPFGISYIDDYAERRNSPFYLGIL 199

  Fly   234 SFLRMLGPAMGFSMVSLCLRLYIDPFKKPL----ITTNDPRWMGAWWIGWILLTFILTISAVFVG 294
            ..:.::|||.|:.|.|..||||:|..|..|    :...||||:||||:|:::...:|:::::...
Zfish   200 FAVTVIGPAFGYIMSSAVLRLYVDIDKMSLNENKLEHGDPRWIGAWWLGFLIAATLLSLTSLPYL 264

  Fly   295 MFPKEMPRAKA---------------RRLKADGEEDIPLAG--RSFQDMLDSLKRLASNKVYV-- 340
            .||::|.:.:.               ::.:.|..|::.|..  :||..:   :.|...|.:|:
Zfish   265 FFPRKMSKEEIEEAPVEPSTEKMIQNKKPETDQIEEVSLTQFLKSFPTI---VLRTLRNPIYLLV 326

  Fly   341 ----YNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKY 401
                .|:.|.:..|..:|      .|:||.|:.::||.|.:..|...:..:..||:..|.::.:.
Zfish   327 VFAQVNLAAMVAGLATFM------GKFIEKQFARTASFSNIMMGGINIPSAMFGIMAGGVILRRL 385

  Fly   402 KPSARAMAAWNFVVDYLTVAGMLCYVLVGCDESDRANSLSIVPTGDS--CSASCVCEYVYYAPVC 464
            ..:.|:.||...:..::::...:..:.:||.    ...:|.:...||  ||.||.|....:.|||
Zfish   386 GLTVRSSAAMCTIAVFISIMFAIPLLFIGCP----TQKISGLNYRDSQQCSNSCYCSDEAFNPVC 446

  Fly   465 SPENITFISACHAGC---TDKAINELGKTIYTGCRCMGNVSSIISLSNVTSLASQSQIAMDGACP 526
            ..:.:.|.|.|||||   ..|.|..:....||.|.|:.:..|             ...|..|.|.
Zfish   447 GSDGVEFRSPCHAGCKIVNIKTIGRIQNVTYTDCGCVKSSGS-------------PGFAFAGPCA 498

  Fly   527 VDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFG 591
            ..|:...:.|:.:.....||.:...:::.::.||.|..:||:|::|...|::.||||:|||:::|
Zfish   499 SGCSNLLIPFMILSSLTCFVASLSHTTSFMMILRTVTPEDKSFAVGIQFMLFRVLAFLPSPVLYG 563

  Fly   592 WMLDSYCLVWGKTCSSKGNCWIYDTKSLRY-----TMNLVCASLI-FLGSF 636
            ..:|:.||||||.||...:|..|:....|:     .:..:|...: ||.||
Zfish   564 TAIDTACLVWGKKCSKSTSCLYYNLDLFRHRFLGLQIFFICGGFVCFLLSF 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	166/606 (27%)
		MFS	55..>410	CDD:119392	102/390 (26%)
		KAZAL_SLC21	447..499	CDD:238650	23/56 (41%)
slco2b1	NP_001032767.2	OATP	27..591	CDD:308646	166/606 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578749
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850