Protein Alignment Oatp58Db and Slco1b2

DIOPT Version :9

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_113838.1
• Gene: Slco1b2 / 58978
• RGDID: 69300
• Length: 687
• Species: Rattus norvegicus
• Alignment Length: 689
• Identity: 180/689 - (26%)
• Similarity: 305/689 - (44%)
• Gaps: 127/689 - (18%)

  Fly    66 AMAFTY---------FTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWV 121
            |::|:|         ...:||.:|:||:||:.|||||..|.:|..:....|:||:.|:.|||:.:
  Rat    33 ALSFSYICKALGGVVMKSSITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSYFGSKLHRPKLI 97

  Fly   122 ALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYG-------------MSESFGASLNITEKNDS 173
            .:|..|:.|..:|...||.|.|..:.|..  .:.|             |:...|.|..|.||.
  Rat    98 GIGCFIMGIGSILTALPHFFMGYYKYAKE--NDIGSLGNSTLTCFINQMTSPTGPSPEIVEKG-- 158

  Fly   174 LCHEKN-----------SNCLERAGDYTPIVLFFIAQFIGGIGCSLFYAPGLSYMDDNSASSKTP 227
             | ||.           .|.|...|: ||||..                 |:||:||.:....|.
  Rat   159 -C-EKGLKSHMWIYVLMGNMLRGIGE-TPIVPL-----------------GISYLDDFAKEGHTS 203

  Fly   228 AMLSWSSFLRMLGPAMGFSMVSLCLRLYID----PFKKPLITTNDPRWMGAWWIGWILLTFILTI 288
            ..|.....:.|:||.:||.|.|:..::|:|    ......||.||.||:||||:.:|:...:...
  Rat   204 MHLGTLHTIAMIGPILGFIMSSVFAKIYVDVGYVDLNSVRITPNDARWVGAWWLSFIVNGLLCIT 268

  Fly   289 SAVFVGMFPKEMPRAKARRL--------KADGEED--IPLAGRSFQD------MLDSLKRLASNK 337
            |::.....||...|::..|.        |.|.|:.  ..|..:..||      .|.||:.:.:|:
  Rat   269 SSIPFFFLPKIPKRSQEERKNSVSLHAPKTDEEKKHMTNLTKQEEQDPSNMTGFLRSLRSILTNE 333

  Fly   338 VYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYK 402
            :||..::.::|.:.|::..:.:..|:||.|:.::||.:....|...:...|..:.:.||::.|:|
  Rat   334 IYVIFLILTLLQVSGFIGSFTYLFKFIEQQFGRTASQANFLLGIITIPTMATAMFLGGYIVKKFK 398

  Fly   403 PSARAMAAWNFVVDYLTVAGMLCYVLVGCDESDRANSLSIVPTG----DS--------CSASCVC 455
            .::..:|.:.|....:..|....|..:.|:....| .|::...|    ||        |::.|.|
  Rat   399 LTSVGIAKFVFFTSSVAYAFQFLYFPLLCENKPFA-GLTLTYDGMNPVDSHIDVPLSYCNSDCSC 462

  Fly   456 EYVYYAPVCSPENITFISACHAGCT----DKAINELGKTIYTGCRCMGNVSSIISLSNVTSLASQ 516
            :...:.|:|....:|:||.|.|||.    ||..|   .|.:..|.|:.|              |.
  Rat   463 DKNQWEPICGENGVTYISPCLAGCKSFRGDKKPN---NTEFYDCSCISN--------------SG 510

  Fly   517 SQIAMDGACP-VDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSV 580
            :..|..|.|| ..|...:..::.:...:.|..|.|..|.:|:.::.|..:.|:.::||.|::...
  Rat   511 NNSAHLGECPRYKCKTNYYFYIILQVTVSFFTAMGSPSLILILMKSVQPELKSLAMGFHSLIIRA 575

  Fly   581 LAFIPSPIVFGWMLDSYCLVWGKT-CSSKGNCWIYDTKSLRYT---MNLVCAS-LIFLGSFWNIG 640
            |..|.:||.:|..:|..|:.|..| |..:|.|.:|:::...::   :||...: .:||   :.:.
  Rat   576 LGGILAPIYYGAFIDRTCIKWSVTSCGKRGACRLYNSRLFGFSYLGLNLALKTPPLFL---YVVL 637

  Fly   641 VWYHAKDMKVFDEDEKTVQ-AKQSDDIELKEKPNDVVTK 678
            :::..:..|  ..|.||:: .:|..|    |...|.|.|
  Rat   638 IYFTKRKYK--RNDNKTLENGRQFTD----EGNPDSVNK 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	166/623 (27%)
		MFS	55..>410	CDD:119392	108/396 (27%)
		KAZAL_SLC21	447..499	CDD:238650	20/63 (32%)
Slco1b2	NP_113838.1	MFS	28..555	CDD:421695	148/563 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..311		5/24 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920