Protein Alignment Oatp58Db and slco1c1

DIOPT Version :9

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_005164528.1
• Gene: slco1c1 / 562772
• ZFINID: ZDB-GENE-041210-50
• Length: 710
• Species: Danio rerio
• Alignment Length: 629
• Identity: 180/629 - (28%)
• Similarity: 297/629 - (47%)
• Gaps: 70/629 - (11%)

  Fly    53 MFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHR 117
            ||::....|....|::.:|...|||.:|:||:||:.:.|:|....:|..:...||:||:.::.||
Zfish    48 MFLVALSFAYFSKALSGSYMKSTITQLERRFDIPSYLIGVIDGSFEIGNLLVIAFVSYFGAKLHR 112

  Fly   118 PRWVALGLIIIAIFCLLMLTPHIFYG--PGEEALRLTEEYGMSESFGASLNITEKNDSLCHEKNS 180
            |:.:|:|.:::::...|:..||...|  ..|.::||:.....|.| ..||:..|.:.|  ...::
Zfish   113 PKIIAIGCLLMSLGTFLIALPHFIIGRYKFETSIRLSVNSSSSLS-PCSLSSAEPSTS--SVPST 174

  Fly   181 NCLERAGDYTPIVLFFIAQFIGGIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGF 245
            .| |.....:..:..|:...:.|||.:.....|:||:||::........:.....:.::||..|:
Zfish   175 GC-EHESRLSMWIYVFLGNILRGIGETPVQPLGISYIDDHALEENAAFYIGCVQTISVIGPVFGY 238

  Fly   246 SMVSLCLRLYID----PFKKPLITTNDPRWMGAWWIGWILLTFILTISAVFVGMFPKEMPRAKAR 306
            .:.|:|.::|:|    ..:...||..|.||:||||:|:::..||..:|||.....||.:|..:.|
Zfish   239 LLGSVCAKIYVDIGFVNMESISITPGDARWVGAWWLGYLIAGFITLLSAVPFWFLPKSLPLPERR 303

  Fly   307 RLKADGE-----EDIPLAGRSFQ------------DMLDSLKRLASNKVYVYNMLASILY---LF 351
            ..|...|     :|..|....:|            |.|.:|:.|..|.||...:..:|:.   |.
Zfish   304 LSKYSPERNSFIKDSALLEHKYQADEPANFLEMAKDFLPTLRSLLGNPVYFLYLCVTIIQFNSLI 368

  Fly   352 GYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVD 416
            |.:.|   .|||||..|.||||.:....|...:...|.|:...|.::.|:|.|....|.:.....
Zfish   369 GMVTY---KPKYIEQHYGQSASKANFLMGVINIPAVALGMFSGGVIMKKFKLSIMGAAKFALGTS 430

  Fly   417 YLTVAGMLCYVLVGCDESDRA------NSLSIVPTGD-----SCSASCVCEYVYYAPVCSPENIT 470
            .|.....|.:..:||:.:..|      |....:...|     ||:|:|.|....:.|||..:.:|
Zfish   431 LLGYFLSLFFFSMGCENASVAGITMSYNGTESLFMADGSLRASCNAACHCPEKNWDPVCGEDGLT 495

  Fly   471 FISACHAGCTDKAINELGKTIYTGCRCMGNVSSIISLSNVTSLASQSQIAMDGAC--PVDCNKQF 533
            ::|.|.|||.....:.: .|::..|.|:|       :.|.|:.|        |.|  ...|::.|
Zfish   496 YVSPCLAGCRTSHGSGM-DTVFEQCSCIG-------VGNQTATA--------GQCNNRESCHRIF 544

  Fly   534 LIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYC 598
            ..|||:.....|:.:.|.:...:|.:||:..:.|:.:|||.::....||.||:||.||.::|:.|
Zfish   545 PYFLALSVITSFIISLGGTPGYMLLIRCIKPQLKSLALGFHTLTTRTLAGIPAPIYFGAIIDTTC 609

  Fly   599 LVWG-KTCSSKGNCWIYDTKSLR-----YTMNLVCAS--LIFLG 634
            |.|| |.|..:|.|.||:|.:.|     .|:.|...|  |..||
Zfish   610 LKWGHKKCGGRGACRIYNTAAYRIAYLGLTLGLRTVSFFLCILG 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	173/605 (29%)
		MFS	55..>410	CDD:119392	106/380 (28%)
		KAZAL_SLC21	447..499	CDD:238650	18/56 (32%)
slco1c1	XP_005164528.1	OATP	48..631	CDD:281175	173/605 (29%)
		MFS	50..461	CDD:119392	113/417 (27%)
		KAZAL_SLC21	470..523	CDD:238650	17/53 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920