Protein Alignment Oatp58Db and Slco4c1

DIOPT Version :10

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001002024.2
• Gene: Slco4c1 / 432363
• RGDID: 1303048
• Length: 724
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 184/676 - (27%)
• Similarity: 303/676 - (44%)
• Gaps: 98/676 - (14%)

  Fly     2 ASEEIEASKFLKDKEAGINVADDEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLA 66
            ||:|...|: |.:.|.|               .||:..|....|||......|::.|    |.||
  Rat    67 ASDEPPGSQ-LSELEEG---------------PCGWRNFHPQCLQRCNNPKGFLLHY----CLLA 111

  Fly    67 MAFTYFTG-----TITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLI 126
            :.......     :|:|:|||:.:.:.::|||:...|||....|.|:|::..|||:|||:|....
  Rat   112 LTQGIVVNGLVNISISTIEKRYEMKSSLTGLISSSYDISFCVLSLFVSFFGERGHKPRWLAFASF 176

  Fly   127 IIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSESFGASLNITEKNDSLCHEKNSNCLERAGDYTP 191
            :|.:..|:...||.|.|          .|.:...|          :..|..:||.   |....|.
  Rat   177 MIGLGALVFSLPHFFSG----------RYELGTIF----------EDTCLTRNST---RCASSTS 218

  Fly   192 IV-----LFFIAQFIGGIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLC 251
            ::     :|.:.|.:.|.|.:..|..|.:::||:..:.|:...:.....:.:||||:|:.:....
  Rat   219 LLSNYFYVFVLGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGYSMSILGPAIGYVLGGQL 283

  Fly   252 LRLYIDPF--KKPLITTNDPRWMGAWWIGWILLTFILTISAVF-VGMFPKEMP-RAKARRLKADG 312
            |.:|||..  :...:|.:||||:||||||: ||.::...|.:. ...|||.:| .||.:..|...
  Rat   284 LTMYIDVAMGQSSDLTEDDPRWLGAWWIGF-LLAWLFAWSLIMPFSCFPKHLPGTAKIQAGKTSQ 347

  Fly   313 ------------EEDIPLAGRSFQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIE 365
                        :|:.   |:|.:|...::|.|..|.|::..:|::.........:..|.||:||
  Rat   348 THQNNSTSFQHMDENF---GKSIKDFPTAVKNLMRNTVFICLVLSTTSEALVTTGFATFLPKFIE 409

  Fly   366 IQYRQSASTSTMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLV- 429
            .|:..::|.:....|...:..:|.|.::.|.::||:|  .:......|.:....||.||.:|.:
  Rat   410 NQFGLTSSFAATLGGAVLIPGAALGQILGGVLVSKFK--MKCKNTMKFALCTSGVALMLSFVFIY 472

  Fly   430 -GCDESDRAN-SLSIVPTGD------SCSASCVCEYVYYAPVCSPENITFISACHAGCTDKAINE 486
             .|:....|. |.|...||:      .|:|:|.|...||.|:|..:.:.:.|.|.|||.:...|.
  Rat   473 AKCENGPFAGVSESYNGTGEMGNLTAPCNANCNCLRSYYYPLCGSDGVQYFSPCFAGCLNSVSNR 537

  Fly   487 LGKTIYTGCRCMGNVSSIISLSNVTSLASQSQI-AMDGACPVDCNKQ--FLIFLAVMCFLKFVGA 548
            ..|..|       |.|.|....::||.|..... |..|.|...|:..  ||....:.....|:..
  Rat   538 KPKAYY-------NCSCIERKVDITSTAESPDFEARAGKCKTQCSNLPIFLGIFFITVIFTFMAG 595

  Fly   549 TGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCW 612
            |..:.::   ||||..:.::.:||...|:..:|..||.||:||..:||.|::|. ..|.:||.||
  Rat   596 TPITVSI---LRCVNHRQRSLALGVQFMLLRLLGTIPGPIIFGVTIDSTCVLWDINECGTKGACW 657

  Fly   613 IYDTKSLRYTMNLVCASLIFLGSFWN 638
            |||...:.:.:..:..:...:..|:|
  Rat   658 IYDNIRMAHMLVAISVTCKVITIFFN 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:460821	169/604 (28%)
Slco4c1	NP_001002024.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..80		5/13 (38%)
		MFS_SLCO4C_OATP4C	100..604	CDD:341021	143/546 (26%)