Protein Alignment Oatp58Db and slco1d1

DIOPT Version :10

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001335015.1
• Gene: slco1d1 / 326845
• ZFINID: ZDB-GENE-030131-5044
• Length: 689
• Species: Danio rerio
• Alignment Length: 709
• Identity: 196/709 - (27%)
• Similarity: 320/709 - (45%)
• Gaps: 110/709 - (15%)

  Fly    45 LQRFATAHMFVIVYGIASCFLAMAF--TYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAF 107
            |:.|..|..||        |.|.||  :|...::|.:|:||::|:.:.|.|....:|..:|..||
Zfish    14 LKMFLAAMCFV--------FFAKAFQGSYMKSSVTQIERRFDVPSSLIGFIDGSFEIGNLFVIAF 70

  Fly   108 LSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSES---FGASLNITE 169
            :||:.::.||||.:|.|.::::....:...||.|.|          :|....:   |.||:|.||
Zfish    71 VSYFGAKLHRPRLIAAGCLVMSAGSFITAMPHFFQG----------QYKYESTISHFSASVNGTE 125

  Fly   170 K------NDSLCH-------EKNSNCLERAGDYTPIVLFFIAQFIGGIGCSLFYAPGLSYMDDNS 221
            .      |.||..       |..:.| |:|...:..:..|:...:.|||.:.....||||:||.|
Zfish   126 NVLPCLTNASLAQDSEIPTVESQAEC-EKASSSSLWLFVFLGNMLRGIGETPVMPLGLSYLDDFS 189

  Fly   222 ASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDPFKKPL--ITTN--DPRWMGAWWIGWILL 282
            ....|...|:....:.::||..||.:.|.|.:||:|.....|  ||.|  |.||:||||:|:::.
Zfish   190 REENTAFYLALIQTVGIMGPMFGFMLGSFCAKLYVDIGTVDLDSITINYKDSRWVGAWWLGFLVT 254

  Fly   283 TFILTISAVFVGMFPKEMPR---------------AKARRLKADGEEDIPLAGRS--------FQ 324
            ..::.::.:.....||.:.|               .:..|...|..:..|.|.:.        .:
Zfish   255 GGVMLLAGIPFWFLPKSLTRQGEPESEKKPGAPEGGEQERFIPDNNKHNPPASKPAPVTMSALAK 319

  Fly   325 DMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAA 389
            |.|.|||:|.||.:||..:...::.:.|::....|.||::|..|.||||.:....|...|...|.
Zfish   320 DFLPSLKKLFSNTIYVLLVCTGLIQVSGFIGMITFKPKFMEQVYGQSASRAIFLIGIMNLPAVAL 384

  Fly   390 GILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGCDESDRANSLSIVPTG-------- 446
            ||:..|:::.::|.:....|....|...|....||....:.||.|..| .|::...|
Zfish   385 GIVTGGFIMKRFKVNVLGAAKICIVASVLAFCSMLIQYFLQCDNSQVA-GLTVTYQGAPEVSYQT 448

  Fly   447 ----DSCSASCVCEYVYYAPVCSPENITFISACHAGC-TDKAINELGKTIYTGCRCMGNVSSIIS 506
                ..|:..|.|...::.|:|:...:|:.|.|.||| |...|.:  :.::..|.|:|  .:::.
Zfish   449 ETLISQCNIGCSCSLKHWDPICASNGVTYTSPCLAGCQTSTGIGK--EMVFHNCSCIG--EALLP 509

  Fly   507 LSNVTSLASQSQIAMDGACP--VDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTF 569
            .:|::        |:.|.||  .||:..|.|::||.....|..|.|.:...::.||.:..:.|:.
Zfish   510 YTNMS--------AVLGQCPRKSDCDFMFKIYMAVTVIGAFFSAVGATPGYIILLRSITPELKSL 566

  Fly   570 SLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCWIYDTKSLRYT-MNLVCASLIF 632
            :||..:::...|..||.||.||.::|..||.|| |.|..:|.|.|||:.:.|.. :.|:.|  ::
Zfish   567 ALGMHTLIVRTLGGIPPPIYFGALIDKTCLKWGLKQCGGRGACRIYDSGAFRNAFLGLIYA--LY 629

  Fly   633 LGSFWNIGVWYH----------AKD-MKVFDEDE---KTVQAKQSDDIELKEKPNDVVT 677
            ..|:...|:.|:          .|| :|..::|.   .|.....|..|...|.|:...|
Zfish   630 SSSYLLFGLLYNRLSHREKKQALKDQLKAPEQDSCGVSTTNGNASSAIVKCENPDQETT 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:460821	177/626 (28%)
slco1d1	NP_001335015.1	MFS	14..558	CDD:475125	157/575 (27%)