Protein Alignment Oatp58Db and Slco6c1

DIOPT Version :10

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_775460.1
• Gene: Slco6c1 / 287006
• RGDID: 708431
• Length: 701
• Species: Rattus norvegicus
• Alignment Length: 713
• Identity: 157/713 - (22%)
• Similarity: 265/713 - (37%)
• Gaps: 151/713 - (21%)

  Fly    24 DEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCF-------LAMAFTYFTGTITTMEK 81
            |.|...|.:...|......|.||||.....|:|.: |||..       ||........::.|:.|
  Rat    59 DPKYSASKEGPFGLGPLVFPCLQRFNNIDCFMIFF-IASVLIHGALFALADMILNLYHSLLTLSK 122

  Fly    82 RFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGE 146
            |.......||.|     :|::. :.|::::..:|:|.:|:|...|::|...:|:..|.
  Rat   123 RELYFMDFSGYI-----VSSLV-AIFVAHFGGKGNRTKWIAAACILMAFGSILLGFPF------- 174

  Fly   147 EALRLTEEYGMSESFGASLNI-TEKNDSLCHEKNSNCLERAG-DYTPIVLFF-IAQFIGGIGCSL 208
                  .:|.:.:|.|..:.: .|:|    ..:|.:|:..:. |.|..:.|| |.|.:.||....
  Rat   175 ------SKYEIMKSGGQRVELCVEEN----KRRNIHCVTNSNPDRTKCICFFIIGQCLNGIAGMP 229

  Fly   209 FYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGF--SMVSLCLRLYIDPFKKPLITTNDPR- 270
            .|..|.:::.|:..:......|:......::|..:|.  .|.:|.     .|.|:.|...:..:
  Rat   230 IYILGKTFILDHVPTRSAGFYLALGHSAHLMGYFLGIFGGMKNLS-----PPPKEKLSAVDSAKI 289

  Fly   271 ---WMGAWWIGWILLTFILTIS-AVFVGM--FPKEMPRAKARRLKADGEEDIPLAGRSFQDMLDS 329
               ....||..::   |:..|| :||:.:  ||..:|          |...:.||.|......|
  Rat   290 HLLLQFGWWKTFL---FVAAISFSVFLVLLCFPTSLP----------GAHKLKLAKRKEPPTFD- 340

  Fly   330 LKRLASNKVY---------VYNMLASILYL----------FGYMPYWIFTPKYIEIQYRQSASTS 375
             |||...|:.         ::.||.:.|.:          |.:.....|.|.:::.|:..:...:
  Rat   341 -KRLKDQKIQPRFKGFVFAIWYMLRNPLLMTQAMCKVSESFAFHTSLEFLPYHLQTQFSITPQIA 404

  Fly   376 TMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGC--------- 431
            :|.||.:.:.....|..:.|.::.:.:.:.:....::.|...::||..|....|.|
  Rat   405 SMLTGLFVIPGGVIGHFLGGLIVDRLEMTNKNKLKFSLVTSVVSVALFLLIFFVECETTKFAGIN 469

  Fly   432 DESDRANSLSIVPTGDSCSASCVCEYVYYAPVCSPENITFISACHAGCTDKAINELGKTIYTGCR 496
            ::.|....|..:..|  |:..|.|....|:.||..:...:.|.|.|||:...:.:..||.| .|.
  Rat   470 EDYDGLGKLGNLTAG--CNYHCACTTSLYSSVCGRDEKEYFSPCFAGCSATKVQQNEKTYY-NCS 531

  Fly   497 CMGNVSSIISLSNVTSLASQSQI-AMDGACPVDCNKQFLIF--------LAVMCFLKFVGATGRS 552
            |       |.....||.|....| |.||.|..:|....|.|        .:.||....:
  Rat   532 C-------IKEGLTTSDADGHFIDATDGTCNSNCLTLPLFFAFYFSATVFSTMCSTPII------ 583

  Fly   553 SNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCWIYDT 616
               |:.|:.||:...:...|....:....|.:|.|.:||......|..|. ..|..:..||||:.
  Rat   584 ---LIILQSVPANFSSLGQGVTVAITKFTASVPEPALFGTASSVACKFWDINACGVREKCWIYNK 645

  Fly   617 KSLRYTMNLVCASLIFLGSFWNIGVWYHAK---------DMKVFD-------EDEKTVQAKQS 663
            .:|.|..               ||:|...|         .:.::|       .|.||...|.|
  Rat   646 TTLVYVF---------------IGIWVSFKLFTALLNIYAIHIYDYVVKGKISDSKTTHVKAS 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:460821	136/622 (22%)
Slco6c1	NP_775460.1	MFS	86..588	CDD:475125	120/564 (21%)