Protein Alignment Oatp58Db and Slco1a6

DIOPT Version :10

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_076207.1
• Gene: Slco1a6 / 28254
• MGIID: 1351906
• Length: 670
• Species: Mus musculus
• Alignment Length: 681
• Identity: 171/681 - (25%)
• Similarity: 296/681 - (43%)
• Gaps: 104/681 - (15%)

  Fly    48 FATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYA 112
            ||...:|::....|.....::..|.:..:|.:|::|||.|.|.|||....::..:....|:||:.
Mouse    16 FAKIKVFLLALIWAYISKILSGVYMSTMLTQLERQFNISTSIVGLINGSFEMGNLLVIVFVSYFG 80

  Fly   113 SRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSESFGASLNITEKNDSLCHE 177
            ::.|||..:.:|..::.:.|.::..||...|          .|....:...:.|:: .|..||.|
Mouse    81 TKLHRPIMIGVGCAVMGLGCFIISLPHFLMG----------RYEYETTISPTSNLS-SNSFLCVE 134

  Fly   178 KNSNCLERAGDYTPIV-----LFFIAQFIG----GIGCSLFYAPGLSYMDDNSASSKTPAMLSWS 233
            ..|..|:...|....|     |.:|...:|    |||.:.....|:||::|.:.|..:|..:...
Mouse   135 NRSQTLKPTQDPAECVKEIKSLMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGIL 199

  Fly   234 SFLRMLGPAMGFSMVSLCLRLYIDP----FKKPLITTNDPRWMGAWWIGWILLTFILTISAVFVG 294
            ...:|:||.:|:.|...|..:|:|.    .....||..|.||:||||||:::...:..::::...
Mouse   200 EVGKMIGPILGYLMGPFCANIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNVLTSIPFF 264

  Fly   295 MFPKEMPR------------AKARRLKADGEEDIPLAGRSFQDMLDSLKRLASNKVYVYNMLASI 347
            .|||.:|:            ||..:.:...:|:.....:.|..|   :|.|..|.:|:..:|.|:
Mouse   265 FFPKTLPKEGLQDNGDGTENAKEEKHRDKAKEENQGIIKEFFLM---MKNLFCNPIYMLCVLTSV 326

  Fly   348 LYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYK---PSARAMA 409
            |.:.|.....|:.|||:|..:..|.:.:....|.:.....:||.||||:::.|.|   ..|..:|
Mouse   327 LQVNGVANIVIYKPKYLEHHFGISTAKAVFLIGLYTTPSVSAGYLISGFIMKKLKITLKKAAIIA 391

  Fly   410 AWNFVVDYLTVAGMLCYVLVGCDES----------------DRANSLSIVPTGDSCSASCVCEYV 458
            ...|:.:.|.   .||..::.||.:                |..|...     ..|:..|.|...
Mouse   392 LCLFMSECLL---SLCNFMLTCDTTPIAGLTTSYEGIQQSFDMENKFL-----SDCNTRCNCLTK 448

  Fly   459 YYAPVCSPENITFISACHAGCTDKAINELGKTIYTGCRCM---GNVSSIISLSNVTSLASQSQIA 520
            .:.|||....:.::|.|.||| :|::......::..|.|:   ||.|:::
Mouse   449 TWDPVCGNNGLAYMSPCLAGC-EKSVGTGANMVFQNCSCIRSSGNSSAVL--------------- 497

  Fly   521 MDGACP--VDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAF 583
              |.|.  .||..:...||.:..|..|..:.......::.|||:.|::|:..:|..:....:.|.
Mouse   498 --GLCKKGPDCANKLQYFLIITVFCCFFYSLATIPGYMVFLRCMKSEEKSLGIGLQAFFMRLFAG 560

  Fly   584 IPSPIVFGWMLDSYCLVWGK-TCSSKGNCWIYDTKSLRYTMNLVCASL---IFLGSFWNIGVWYH 644
            ||:||.||.::|..||.||. .|...|.|..|:..|.|.....:.|:|   |.|.||:.:.:
Mouse   561 IPAPIYFGALIDRTCLHWGTLKCGEPGACRTYEVSSFRRLYLGLPAALRGSIILPSFFILRL--- 622

  Fly   645 AKDMKVFDEDEKTVQAKQSDDIELKE-KPND 674
            .:.:::..:.:       |.:|||.| ||.:
Mouse   623 IRKLQIPGDTD-------SSEIELAETKPTE 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:460821	154/615 (25%)
Slco1a6	NP_076207.1	oat	1..625	CDD:273279	164/651 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	633..670		7/21 (33%)