Protein Alignment Oatp58Db and Slco4c1

DIOPT Version :10

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_766246.1
• Gene: Slco4c1 / 227394
• MGIID: 2442784
• Length: 722
• Species: Mus musculus
• Alignment Length: 676
• Identity: 184/676 - (27%)
• Similarity: 305/676 - (45%)
• Gaps: 100/676 - (14%)

  Fly     2 ASEEIEASKFLKDKEAGINVADDEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLA 66
            ||:|...|: |.:.|.|               .||:..|....|||..|...|::.|    |.||
Mouse    67 ASDEPPGSQ-LSELEEG---------------PCGWRGFHPQCLQRCNTPQGFLLHY----CLLA 111

  Fly    67 MAFTYFTG-----TITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLI 126
            :.......     :|:|:|||:.:.:.::|||:...|||....|.|:|::..|||:|||:|....
Mouse   112 LTQGIVVNGLVNISISTIEKRYEMKSSLTGLISSSYDISFCVLSLFVSFFGERGHKPRWLAFASF 176

  Fly   127 IIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSESFGASLNITEKNDSLCHEKNSNCLERAGDYTP 191
            :|.:..|:...||.|.|          .|.:...|          :..|..:||.   |....|.
Mouse   177 MIGLGALVFSLPHFFSG----------RYELGSIF----------EDTCLTRNST---RCSSSTS 218

  Fly   192 IV-----LFFIAQFIGGIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLC 251
            ::     :|.:.|.:.|.|.:..|..|.:::||:..:.|:...:.....:.:||||:|:.:....
Mouse   219 LLSNYFYVFVLGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGYSMSILGPAIGYVLGGQL 283

  Fly   252 LRLYID--PFKKPLITTNDPRWMGAWWIGWILLTFILTISAVF-VGMFPKEMP-RAKARRLKAD- 311
            |.:|||  ..:...:|.:||||:||||||: ||.::...|.:. ...|||.:| .||.:..|..
Mouse   284 LTMYIDIAMGQSSDLTEDDPRWLGAWWIGF-LLAWLFAWSLIMPFSCFPKHLPGTAKIQAGKTSQ 347

  Fly   312 -----------GEEDIPLAGRSFQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIE 365
                       .:|:.   |:|.:|...::|.|..|.|::..:|::.........:..|.||:||
Mouse   348 THQNNSTSFQHTDENF---GKSIKDFPTAVKNLMRNTVFICLVLSTTSEALITTGFATFLPKFIE 409

  Fly   366 IQYRQSASTSTMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLV- 429
            .|:..::|.:....|...:..:|.|.::.|.::||:|  .:......|.:....||.:|.:|.:
Mouse   410 NQFGLTSSFAATLGGAVLIPGAALGQILGGVLVSKFK--MKCKNTMKFALCTSGVALVLSFVFIY 472

  Fly   430 -GCDESDRAN-SLSIVPTGD------SCSASCVCEYVYYAPVCSPENITFISACHAGCTDKAINE 486
             .|:....|. |.|...||:      .|:|:|.|...||.|:|..:.|.:.|.|.|||.:...|.
Mouse   473 AKCENEPFAGVSESYNGTGEMGNLTAPCNANCNCLRSYYYPLCGSDGIQYFSPCFAGCLNSVSNR 537

  Fly   487 LGKTIYTGCRCMGNVSSIISLSNVTSLASQSQI-AMDGACPVDCNKQ--FLIFLAVMCFLKFVGA 548
            ..| :|..|.|:..        .:||.|..:.. |..|.|...|:..  ||....:.....|:..
Mouse   538 KPK-VYYNCSCIER--------KITSTAESTDFEAKAGKCRTRCSNLPIFLGIFFITVIFTFMAG 593

  Fly   549 TGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCW 612
            |..:.::   ||||..:.::.:||...|:..:|..||.||:||.::||.|::|. ..|..||.||
Mouse   594 TPITVSI---LRCVNHRHRSLALGVQFMLLRLLGTIPGPIIFGVIIDSTCVLWDVNECGIKGACW 655

  Fly   613 IYDTKSLRYTMNLVCASLIFLGSFWN 638
            |||...:.:.:..:..:...:..|:|
Mouse   656 IYDNIKMAHMLVAISVTCKVITIFFN 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:460821	168/604 (28%)
Slco4c1	NP_766246.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		5/14 (36%)
		MFS_SLCO4C_OATP4C	100..602	CDD:341021	142/546 (26%)