Protein Alignment Oatp58Db and Slco3a1

DIOPT Version :9

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_076397.2
• Gene: Slco3a1 / 108116
• MGIID: 1351867
• Length: 710
• Species: Mus musculus
• Alignment Length: 635
• Identity: 175/635 - (27%)
• Similarity: 285/635 - (44%)
• Gaps: 94/635 - (14%)

  Fly    57 VYGIASCFLAMA----FTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHR 117
            ::.::.|.|.:|    ..|....:||:|:|||:.:...|:|....:|..:....|:||:.:||||
Mouse    41 IFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHR 105

  Fly   118 PRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSES---FGASLNITEKNDSLCHEKN 179
            ||.:..|.|::|:..||...|..          ||.:|.....   :||     |..| :|....
Mouse   106 PRLIGCGGIVMALGALLSALPEF----------LTHQYKYEAGEIRWGA-----EGRD-VCATNG 154

  Fly   180 SN----------CLERAGDYTPIVLFFIAQFIGGIGCSLFYAPGLSYMDDNSASSKTPAMLSWSS 234
            |:          |..|.......:|...||.:.|||.:.....|:||:||:.....:...:....
Mouse   155 SSSDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILF 219

  Fly   235 FLRMLGPAMGFSMVSLCLRLYIDPF----KKPLITTNDPRWMGAWWIGWILLTFILTISAVFVGM 295
            .:.:.|||.||.:.|.|.::|:|..    ....||.:||||:||||.|::|...:|..|::.:..
Mouse   220 TMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFG 284

  Fly   296 FPKEMP----------------RAKARRLKADGEEDIPLAGRSFQDMLDSL-------KRLASNK 337
            ||:.:|                |...|...::|....||...|.......|       |.|.||.
Mouse   285 FPQSLPPHSDPGMESEQAMLPEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNP 349

  Fly   338 VYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYK 402
            |:...:||:.:.:.....:..|..||:|.|:..:.|::....|..|:..:..||.:.|.::.|..
Mouse   350 VFTCIVLAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLS 414

  Fly   403 PSARAMAAWNFVVDYLTVAGMLCYVLVGCDESDRA--------NSL--SIVPTGDSCSASCVCEY 457
            .||........:|:.::.|..:.::.:|||....|        ||.  |.:.....|:.:|.|:.
Mouse   415 LSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVRYGNNSARGSALDPYSPCNNNCECQT 479

  Fly   458 VYYAPVCSPENITFISACHAGCTDKAINELGKTIYTGCRCMGNVSSIISLSNVTSLASQSQIAMD 522
            ..:.|||..:.||::|||.|||        ..|..|||.|:            |::..::...:.
Mouse   480 DSFTPVCGADGITYLSACFAGC--------NSTNLTGCACL------------TTVPPENASVVP 524

  Fly   523 GACP-VDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPS 586
            |.|| ..|.:.||.||.|||....:||..::.::::.:|.|..:.|:::||...::..:|.|||.
Mouse   525 GKCPSPGCQEAFLTFLCVMCVCSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPP 589

  Fly   587 PIVFGWMLDSYCLVWGKTCSSKGNCWIYDTKSLRYTMNLVCASLIFLGSF 636
            |::||..:||.||.|...|..:|.|.:||....||   |..:..|.|.||
Mouse   590 PLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVYRY---LYVSIAIALKSF 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	168/616 (27%)
		MFS	55..>410	CDD:119392	104/396 (26%)
		KAZAL_SLC21	447..499	CDD:238650	19/51 (37%)
Slco3a1	NP_076397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		MFS_SLCO3_OATP3	39..563	CDD:340960	146/557 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850