Protein Alignment Oatp58Db and Slco2b1

DIOPT Version :9

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_011239939.1
• Gene: Slco2b1 / 101488
• MGIID: 1351872
• Length: 697
• Species: Mus musculus
• Alignment Length: 662
• Identity: 175/662 - (26%)
• Similarity: 287/662 - (43%)
• Gaps: 118/662 - (17%)

  Fly    48 FATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYA 112
            |.....||:.:.:......|...|...:|:|:||||.:.::||||:...|::..|....|:||:.
Mouse    51 FHNIKFFVLCHSLLQLTQLMISGYLKSSISTVEKRFGLSSQISGLLAAFNEVGNVSLILFVSYFG 115

  Fly   113 SRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSESFGASLNITEKNDSLCHE 177
            ||.||||.:..|.:::|...|||..||....|        ..|..|.|...||:.   ..|||..
Mouse   116 SRVHRPRMIGYGALLVATAGLLMALPHFISEP--------YRYDHSSSDNRSLDF---EASLCLP 169

  Fly   178 ---------KNSNCLE--RAGDYTPIVLFFIAQFIGGIGCSLFYAPGLSYMDDNSASSKTPAMLS 231
                     .|.:|..  .....|.:.:.|.||.:.|||.......|:||:||.:..|.:|..:.
Mouse   170 TTMAPASALSNGSCSSHTETKHLTMVGIMFAAQTLLGIGGVPIQPFGISYIDDFAHHSNSPLYIG 234

  Fly   232 WSSFLRMLGPAMGFSMVSLCLRLYIDPFKKP----LITTNDPRWMGAWWIGWILLTFILTISAVF 292
            ....:..:||.:.:.:.||.||||:|..:.|    .:|..||||:||||:|:::.:.::.:::..
Mouse   235 ILFGITTMGPGLAYGLGSLMLRLYVDIDRMPEGGINLTPKDPRWVGAWWLGFLISSGLVVLASSP 299

  Fly   293 VGMFPKEMPRAK----ARRLKADGEEDIPLAGRSFQDMLDSLKRLAS-------------NKVYV 340
            ...||:|||:.|    .||............|.......:.||:.|.             .||:.
Mouse   300 YFFFPREMPKEKHEFHFRRKVLASAASTASKGEDLSSQHEPLKKQAGLAQIAPDLTLVQFVKVFP 364

  Fly   341 YNMLASILYLFGYMPYWI------------------FTPKYIEIQYRQSASTSTMATGTWALGFS 387
            ..:|.::.:     |.::                  |.||::|.|:..:||.:.|..|...:...
Mouse   365 RVLLRNLRH-----PIFLLVVLSQVCTSSMVAGMATFLPKFLERQFSITASFANMLLGCLTIPLV 424

  Fly   388 AAGILISGYVISKYKPSARAMAAWNFVVDYLTVAG-MLCYV------LVGCDESDRA---NSLSI 442
            ..||::.|.::.:...|....:|       |.:.| :||.:      .:||.....|   ..|..
Mouse   425 IVGIMMGGVLVKRLHLSPVQCSA-------LCLLGSLLCLLFSVPLFFIGCSTHQIAGITQDLGA 482

  Fly   443 VPTGDS----CSASCVCEYVYYAPVC-SPENITFISACHAGCTDKAINE-LGKT--IYTGCRCMG 499
            .| |.|    ||..|.|:...:.||| :...:.:.:.||||||.:.:.| |||:  .||.|.|:.
Mouse   483 QP-GPSLFPGCSEPCSCQSDDFNPVCDTSAYVEYTTPCHAGCTGRVVQEALGKSQVFYTNCSCVA 546

  Fly   500 NVSSIISLSNVTSLASQSQIAMDGACPVDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPS 564
            ...::.:                |:|...|::..|.|:.:......:.:...:.:.:|.||.|..
Mouse   547 GNGTVPA----------------GSCESACSRLVLPFIVLFSLGAGLASITHTPSFMLILRGVKK 595

  Fly   565 KDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWGKTCSSKGNCWIYDTKSLRYTM------ 623
            :|||.::|...|:..|||::|||::.|..:|:.|:.|..||..:..|..||...||...
Mouse   596 EDKTLAVGMQFMLLRVLAWMPSPVIHGSAIDTTCVHWALTCGRRAVCRYYDHDLLRNRFIGLQFF 660

  Fly   624 ----NLVCASLI 631
                :|||.:|:
Mouse   661 FKSGSLVCFTLV 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	168/633 (27%)
		MFS	55..>410	CDD:119392	105/404 (26%)
		KAZAL_SLC21	447..499	CDD:238650	22/59 (37%)
Slco2b1	XP_011239939.1	MFS	54..591	CDD:391944	145/576 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6182
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.800