Protein Alignment Oatp58Db and slco2a1

DIOPT Version :9

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001135668.1
• Gene: slco2a1 / 100216228
• XenbaseID: XB-GENE-5814577
• Length: 637
• Species: Xenopus tropicalis
• Alignment Length: 695
• Identity: 181/695 - (26%)
• Similarity: 314/695 - (45%)
• Gaps: 111/695 - (15%)

  Fly    18 GINVADDEKRLNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKR 82
            ||.:. |.|..:.|.|.|...||.        ...:||:.:.:......:...||...:||:|||
 Frog     2 GIKLV-DSKADSKSITGCKKGIFN--------NIKVFVVCHALLQLSQLLYSAYFKSCLTTIEKR 57

  Fly    83 FNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEE 147
            |.:.:..|||::..::||......|:||:.||.||||.:.:|.:::|:...|:..||.
 Frog    58 FGLSSSSSGLLSSIHEISNAVLIIFVSYFGSRVHRPRVIGVGGLLLALGTFLLTVPHF------- 115

  Fly   148 ALRLTEEYGMSESFGASLNITEKND-SLCHEKNS--NCLERAGDYTPI----------VLFFIAQ 199
               ::|:|..:|     ||...::. .||..:|.  :| :..|.:.|:          .:..:.|
 Frog   116 ---VSEKYQYTE-----LNSGNRSQVLLCTGENRTFHC-KTQGQHLPVTTNNGGSSMWAIMVVGQ 171

  Fly   200 FIGGIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDPFKKPL- 263
            .:.|||.......|:||:||.:..:.:...::....:.:.|||.|:.:.|:.||:::|..:..|
 Frog   172 LLAGIGTVPIQPFGISYVDDFAEPNNSALYIAILFAVAVFGPAFGYLLGSVVLRMFVDIGRVNLE 236

  Fly   264 ---ITTNDPRWMGAWWIGWILLTFILTISAVFVGMFPKEMPRAKARRLKADGEE-------DIPL 318
               :|..||||:||||:|.::.:..|.|:::....|||:|    .|..|...||       |:..
 Frog   237 HVDLTVADPRWIGAWWLGLLIASGCLVITSIPYFFFPKQM----LRNEKPAPEENVLRKIPDVKA 297

  Fly   319 AGRSFQDMLDS----LKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMAT 379
            ...|..|.:..    ::||.:|.:::..:|....:.........|..||:|.||..|.|.:....
 Frog   298 EEGSLSDFIKKFPRYVRRLITNPLFLMLVLCQCSFSSVIAALSTFLNKYLEKQYSSSTSYANFLI 362

  Fly   380 GTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVL--VGC----------D 432
            |...|..:|.|:||.|.::.::..|.:.:.  .|.:..|.::.:||..|  :||          :
 Frog   363 GAVNLPTAALGMLIGGIIMKRFCISLQIIP--RFALAILLLSILLCVPLFFMGCSTQALEMGMVE 425

  Fly   433 ESDRANSLSIVPTGDSCSASCVCEYVYYAPVCSPENITFISACHAGCTDKAINELGK---TIYTG 494
            .|...|:||      :|::.|.|....:.|||....:.::|.|||||  :|.|:...   .:|..
 Frog   426 HSTSGNTLS------TCTSQCACPEYAFQPVCGSNGVEYLSPCHAGC--RAFNQTSSEKLRMYRN 482

  Fly   495 CRCMGNVSSIISLSNVTSLASQSQIAMDGACPVDCNKQFLIFLAVMCFLKFVGATGRSSNLLLAL 559
            |.|:.:.|.             ...|..|:||..|:...|..:.::.|...:.....:...::.|
 Frog   483 CSCITDTSG-------------EGTAQTGSCPTSCSHLLLPVMFLISFAGLIACLTHNPLYMMVL 534

  Fly   560 RCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWGKTCS-SKGNCWIYDTKSLR--- 620
            |.|...:|:|::|...::...||::|:|.:||.::||.||||.::|| ::|.|..|:...||
 Frog   535 RVVRQDEKSFAIGVQFLLMRFLAWLPAPALFGLVIDSTCLVWDRSCSGNRGACRYYNNDLLRNRY 599

  Fly   621 --YTMNLVCASLIFLGSFWNIGVWYHAKDMKVFDEDEKTVQAKQS 663
              ..|......::.|.:.    .|      ||....|..||.|:|
 Frog   600 LGLQMGYKILGILLLCAI----AW------KVSKRKEYNVQEKES 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	160/609 (26%)
		MFS	55..>410	CDD:119392	100/382 (26%)
		KAZAL_SLC21	447..499	CDD:238650	17/54 (31%)
slco2a1	NP_001135668.1	MFS	25..535	CDD:391944	137/552 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920