Protein Alignment Oatp58Db and slco2b1

DIOPT Version :9

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_031751477.1
• Gene: slco2b1 / 100125037
• XenbaseID: XB-GENE-6046634
• Length: 663
• Species: Xenopus tropicalis
• Alignment Length: 684
• Identity: 179/684 - (26%)
• Similarity: 308/684 - (45%)
• Gaps: 92/684 - (13%)

  Fly    28 LNSSDTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGL 92
            |:...|.|         ...|....:||:.:|.......:...|...:|:|:||||.|.::.||:
 Frog    21 LHQKSTRC---------CHPFNNIKVFVLCHGFLQLSQLLLSGYLRSSISTIEKRFGISSQTSGI 76

  Fly    93 ITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGM 157
            ::..|:|.......|:||:.||.||||::..|.||:.....||..||...||        .||..
 Frog    77 LSSFNEIGNTVLIVFVSYFGSRVHRPRFIGCGAIIVCAAGFLMSLPHFIMGP--------YEYDK 133

  Fly   158 SESFGASL--NIT---EKNDSLCHEKNSNCLERAGDYTPIVLF--FIAQFIGGIGCSLFYAPGLS 215
            |.   |||  |:|   :.|..:....|..|:|........|||  |:.|.:.|||.......|:|
 Frog   134 SV---ASLLSNVTDICQPNGPIKSSDNDQCVEGVQKANKNVLFILFLGQILLGIGSVPIQPFGIS 195

  Fly   216 YMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDPFK----KPLITTNDPRWMGAWW 276
            |:||.::...:|..:.....:.::||.:.|.:.|..||.|:|..|    :..:|..||||:||||
 Frog   196 YIDDFASKRNSPLYIGILFAVTVMGPGVAFILGSAMLRFYVDIDKLSADEITLTPKDPRWIGAWW 260

  Fly   277 IGWILLTFILTISAVFVGMFPKEMPR------------AKARRLKADGEEDIPLAGRSFQDMLDS 329
            :|:::...::.|:::...:||:|||:            :....:|:..||:..|....|..:...
 Frog   261 LGYLVAGSVVAIASIPYFIFPREMPKQGPSEKPEEPKPSLMDEIKSKTEENEKLTLSQFIKVFPK 325

  Fly   330 -LKRLASNKVYVYNMLASILYLFGYMPYWI-----FTPKYIEIQYRQSASTSTMATGTWALGFSA 388
             |.|...|.|::..:||.     |.|...:     |..|::|.|:..:||.:.:..|:..:..:.
 Frog   326 VLFRTVKNPVFILIVLAQ-----GNMSAMVCGLATFMAKFLERQFSITASLANLLIGSANIPAAM 385

  Fly   389 AGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGCD-------ESDRANSLSIVPTG 446
            :||::.|.::.:::.:.:..|....:...:.:...:..|.:||.       ..|...|..|....
 Frog   386 SGIVLGGIIMKRHRLTPKQSALMCVIGLIICIFTAIPLVFLGCSTQQFASPRMDHQGSSGIWQNV 450

  Fly   447 DSCSASCVCEYVYYAPVCSPENITFISACHAGCTDKAINELGKTI--YTGCRCMGNVSSIISLSN 509
            ..||..|.|....:.|||..:.:.:||.|:|||......|....:  ||.|.|:....|
 Frog   451 SECSGGCQCSSAAFNPVCGTDGVEYISPCYAGCGAVQFGESPTEVLNYTRCTCIPAAGS------ 509

  Fly   510 VTSLASQSQIAMDGACPVDCNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFG 574
                      |..|:|...|.:..:.|:.:.|....:.:..::.:.:|.||.|...||:.::|..
 Frog   510 ----------AKPGSCGTVCGQLLVPFMVLSCLAGGLASMAQTPSFMLILRSVKPTDKSLAIGIQ 564

  Fly   575 SMVYSVLAFIPSPIVFGWMLDSYCLVWGKTCSSKGNCWIYDTKSLRYTMNLVCASLIF-LGSFWN 638
            .|:..:||::|.|:::|.::||.|::||:.|..|.:|..||...||  ...:...::| :|
 Frog   565 FMLLRILAWLPGPVMYGSVIDSTCILWGQKCGKKTSCQYYDNNLLR--QRFIGLQILFEIG---- 623

  Fly   639 IGVWYHAKDMKVFDEDEKTVQAKQSDDIELKEKP 672
             |:.:......|....|| |.|::|    ::|.|
 Frog   624 -GLIFFTAVFFVLRRREK-VSAEKS----MRENP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:281175	162/603 (27%)
		MFS	55..>410	CDD:119392	106/383 (28%)
		KAZAL_SLC21	447..499	CDD:238650	18/53 (34%)
slco2b1	XP_031751477.1	MFS	35..550	CDD:421695	140/546 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010