Protein Alignment Oatp58Da and Slco1a5

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_110465.1
• Gene: Slco1a5 / 80900
• RGDID: 70985
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 171/666 - (25%)
• Similarity: 298/666 - (44%)
• Gaps: 68/666 - (10%)

  Fly    56 GPSMQRFATEH--------MYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGND 112
            |.:.:|.||..        |:::....|....:::..|.|..:|.:|:::.|||.:.|.|:...:
  Rat     2 GETEKRVATHEVRCFSKIKMFLLALTWAYVSKSLSGIYMNTMLTQIERQFDIPTSIVGFINGSFE 66

  Fly   113 ISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLT 177
            |..:|....:.|:....|||..:|:|.:.:...|.|.|..|||.|..|....::......:.:..
  Rat    67 IGNLLLIIFVSYFGTKLHRPIMIGVGCVIMGLGCFLMSLPHFLMGRYEYETTISPTSNLSSNSFL 131

  Fly   178 NQERDKKLCQPT--AGGCVQEEVGL-WVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTP 239
            ..|...:..:||  ...|::|...| |   :::....:|.|:|:.....|||:|::|......:|
  Rat   132 CMENRSQTLKPTQDPAECIKEMKSLMW---IYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSP 193

  Fly   240 AMLSMSTFLRMLGPAIGYSLAAVCLRLYIEP----TLEPLIGQEDPRWLGAWWLGWLVLAAITLV 300
            ..:.:....::.||.:|..|.:.|..:|::.    |.:..|...|.||:||||:|:|:.|.:.::
  Rat   194 LYIGILETGKVFGPIVGLLLGSFCASIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLICAGVNIL 258

  Fly   301 SAILLFMFPKQLPSARKRRLQ--------LKQDERKQSLPLNERSLA-DMMKTVKKLSKNKVYVY 356
            |:|..|.|||.||   |..||        .|:::.::......|.:. |.:..:|.||.|.:|:.
  Rat   259 SSIPFFFFPKTLP---KEGLQDDVDGTNNDKEEKHREKAKEENRGITKDFLPFMKSLSCNPIYML 320

  Fly   357 NTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSAR 421
            ..:.|:|....::..:.|.|||:|.||.:|.|...:..|...|.....|.|:.|:::.|:|.:.:
  Rat   321 LILTSVLQINAFINMFTFLPKYLEQQYGKSTAEVVLLIGVYNLPPICIGYLLIGFIMKKFKITVK 385

  Fly   422 AMAAWNAIVDFVTVAGILCYVAIGCEGSDRLNTLTTLSAG------------NSCSASCHCDYVH 474
            ..|.....:..........:..|.|:... :..||....|            ..|:..|.|....
  Rat   386 KAAYMAFCLSLFEYLLYFLHFMITCDNFP-VAGLTASYEGVHHPLYVENKVLADCNRGCSCSTNS 449

  Fly   475 YAPVCSADNITFISACHAGCSERTKDALG---RTIYTGCECLGSSSLNSEPESQFAVDGTCP--V 534
            :.|||..:.:.::|||.|||    |.::|   ..::..|.|:.||..:|      ||.|.|.  .
  Rat   450 WDPVCGDNGLAYMSACLAGC----KKSVGTGTNMVFQNCSCIRSSGNSS------AVLGLCKKGP 504

  Fly   535 DCFNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGW 599
            :|.|:...||.:......:.:.:.....::.|||:.|:||:..:||.:....:...||:||:||.
  Rat   505 ECANKLQYFLIMSVIGSFIYSITAIPGYMVLLRCIKPEEKSLGIGLHAFCTRVFAGIPAPIYFGA 569

  Fly   600 LIDNYCLVWGK-TCSNKGNCWLYDTKSMRYALNLSAAFFIFLGGFLNIAVWYHAKNLKIFDEEES 663
            |||..||.||. .|...|.|.:|:..:.|       ..::.|...|..:.:..|..:.|...:..
  Rat   570 LIDRTCLHWGTLKCGEPGACRMYNINNFR-------RIYLVLPAALRGSSYLPALFILILMRKFQ 627

  Fly   664 SPK--DSLKNKEVEMK 677
            .|.  ||.:.:..|||
  Rat   628 FPGEIDSSETELAEMK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	156/592 (26%)
		MFS	69..>425	CDD:119392	97/371 (26%)
		KAZAL_SLC21	462..514	CDD:238650	16/54 (30%)
Slco1a5	NP_110465.1	oat	1..625	CDD:273279	165/646 (26%)
		MFS	21..>397	CDD:119392	99/381 (26%)
		KAZAL_SLC21	436..487	CDD:238650	15/54 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920