Protein Alignment Oatp58Da and Slco1a3

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_110464.2
• Gene: Slco1a3 / 80899
• RGDID: 621387
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 179/668 - (26%)
• Similarity: 299/668 - (44%)
• Gaps: 79/668 - (11%)

  Fly    75 AGC-------VMTMTFAY----FNGT-----ITTLEKRYKIPTKVSGIISVGNDISTMLTAAILG 123
            |||       :|.:|.||    .:||     :|.:|:::.|||.:.|.|:...:|..:|....:.
  Rat    13 AGCFAKIKVFLMALTCAYVSKSLSGTFMSSMLTQIERQFGIPTAIVGFINGSFEIGNLLLIIFVS 77

  Fly   124 YYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQERDKKLCQP 188
            |:....|||..:|:|...:...|.:.|..|||.|..|....:.......:.:....|...:...|
  Rat    78 YFGMKLHRPIVIGVGCAVMGLGCFIISLPHFLMGRYEYETTILPTSNLSSNSFLCMENQTQTLNP 142

  Fly   189 T--AGGCVQEEVGL-WVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRM 250
            .  ...||:|...| |   :::....:|.|:|:.....||::|:::......:|..:.:....:|
  Rat   143 AQDPAECVKEVKSLMW---IYVLVGNIIRGIGETPIMPLGVSYIENFAKSENSPLYIGILETGKM 204

  Fly   251 LGPAIGYSLAAVCLRLYIEP----TLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQ 311
            :||..|..|.:.|..:|::.    |.:..|...|.||:||||:|:||.|.:.::.:|..|.|||.
  Rat   205 IGPIFGLLLGSFCASIYVDTGSVNTDDLTITPTDIRWVGAWWIGFLVCAGVNILISIPFFFFPKT 269

  Fly   312 LPSARKRRLQ--------LKQDERKQSLPLNERSLA-DMMKTVKKLSKNKVYVYNTMASILYFFG 367
            ||   |..||        .|:::.::.....:|.:. |....:|.||.|.:|:..|:.|:|....
  Rat   270 LP---KEGLQENVDGTENAKEEKHREKAKEEKRGITKDFFPFLKSLSCNPIYMLFTLISVLQVNA 331

  Fly   368 YMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDF 432
            :.:|:.|.|||:|.||.:|.|......|...|.....|.||:|:::.|:|.:.:..|.....:..
  Rat   332 FNIYFSFLPKYLENQYGKSTAEVIFLMGVYNLPAICIGYLIAGFMMKKFKITVKTAAFLAFCLSL 396

  Fly   433 VTVAGILCYVAIGCEGSDRLNTLTTLSAGNS-----------------CSASCHCDYVHYAPVCS 480
            ...:...|...|.|:      .:......||                 |:..|.|....:.|||.
  Rat   397 SEYSFGFCNFLITCD------NVPVAGLTNSYERDQKPLYLENNVLADCNTRCSCLTKTWDPVCG 455

  Fly   481 ADNITFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQFAVDGTC---PVDCFNEFLI 542
            .:.:.::|||.||| |::.......::..|.|:.|      |.:..||.|.|   | :|.|:...
  Rat   456 DNGLAYMSACLAGC-EKSVGTGTNMVFHNCSCIQS------PGNSSAVLGLCNKGP-ECTNKLQY 512

  Fly   543 FLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLV 607
            .|.:..||.::.:.:.....::.|||:..:||:..:|:.:....:...||:||:||.|||..||.
  Rat   513 LLILSGFLSILYSFAAIPGYMVFLRCIKSEEKSLGIGIHAFCIRVFAGIPAPIYFGALIDRTCLH 577

  Fly   608 WG-KTCSNKGNCWLYDTKSM-RYALNLSAAF--FIFLGGFLNIAVWYHAKNL--KIFDEEESSPK 666
            || :.|...|.|.:||..|. |..|.:|||.  ..:|..|: |.:.....:|  ||...|....:
  Rat   578 WGTQKCGAPGACRMYDINSFRRIYLGMSAALRGSSYLPAFV-IVILTRKFSLPGKINSSEMEIAE 641

  Fly   667 DSLKNKEVEMKTIDSNPE 684
            ..|..||.:...:..||:
  Rat   642 MKLTEKESQCTDVHRNPK 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	161/603 (27%)
		MFS	69..>425	CDD:119392	104/381 (27%)
		KAZAL_SLC21	462..514	CDD:238650	17/68 (25%)
Slco1a3	NP_110464.2	oat	1..625	CDD:273279	170/632 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820