Protein Alignment Oatp58Da and slco2b1

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001032767.2
• Gene: slco2b1 / 792084
• ZFINID: ZDB-GENE-051023-6
• Length: 677
• Species: Danio rerio
• Alignment Length: 625
• Identity: 179/625 - (28%)
• Similarity: 297/625 - (47%)
• Gaps: 72/625 - (11%)

  Fly    58 SMQRFATEHMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAIL 122
            ||..|.....:|:.:|:......:...|...:|||:||||...:..||:::..|::...:....:
Zfish    18 SMGLFNNIKFFVLCHGMLQLSQLLVSGYLKASITTIEKRYGFSSSKSGLLAAFNEVGNTVLIVFV 82

  Fly   123 GYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQERDKKLCQ 187
            .::....||||.:|||.:.......|.:..||:           .|..:..|.::|...:..|||
Zfish    83 SFFGSRVHRPRCIGIGGMIASMGVFLIALPHFI-----------SEKYEYTEFISNTRLNSSLCQ 136

  Fly   188 -------PTAGGCVQEEVGLWVPQV----FLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAM 241
                   ||   |.|.:..   ||:    .|...||:.|:|.......||:|:||...:..:|..
Zfish   137 TQDIESSPT---CSQNDTD---PQLGVYPILLLGQLLLGIGGVPIQPFGISYIDDYAERRNSPFY 195

  Fly   242 LSMSTFLRMLGPAIGYSLAAVCLRLYIE----PTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSA 302
            |.:...:.::|||.||.:::..||||::    ...|..:...||||:||||||:|:.|.:..:::
Zfish   196 LGILFAVTVIGPAFGYIMSSAVLRLYVDIDKMSLNENKLEHGDPRWIGAWWLGFLIAATLLSLTS 260

  Fly   303 ILLFMFPKQL-----------PSARKRRLQLKQDERKQSLPLNERSLADMMKT----VKKLSKNK 352
            :....||:::           ||..| .:|.|:.|..|   :.|.||...:|:    |.:..:|.
Zfish   261 LPYLFFPRKMSKEEIEEAPVEPSTEK-MIQNKKPETDQ---IEEVSLTQFLKSFPTIVLRTLRNP 321

  Fly   353 VYVYNTMASILYFFGYMVYWI--FTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISK 415
            :|:....|.:  ....||..:  |..|:||.|:.::|:.:.:..|.:.:..:..||:..|.::.:
Zfish   322 IYLLVVFAQV--NLAAMVAGLATFMGKFIEKQFARTASFSNIMMGGINIPSAMFGIMAGGVILRR 384

  Fly   416 YKPSARAMAAWNAIVDFVTVAGILCYVAIGCEGSDRLNTLTTLSAGNSCSASCHCDYVHYAPVCS 480
            ...:.|:.||...|..|:::...:..:.|||. :.:::.|....: ..||.||:|....:.|||.
Zfish   385 LGLTVRSSAAMCTIAVFISIMFAIPLLFIGCP-TQKISGLNYRDS-QQCSNSCYCSDEAFNPVCG 447

  Fly   481 ADNITFISACHAGCSERTKDALGR---TIYTGCECLGSSSLNSEPESQFAVDGTCPVDCFN---E 539
            :|.:.|.|.|||||.......:||   ..||.|.|:.||.     ...||..|.|...|.|   .
Zfish   448 SDGVEFRSPCHAGCKIVNIKTIGRIQNVTYTDCGCVKSSG-----SPGFAFAGPCASGCSNLLIP 507

  Fly   540 FLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNY 604
            |:|...:.||   |.:.|.:|:.::.||.:.|::|:||:|:..|...:|.|:|||:.:|..||..
Zfish   508 FMILSSLTCF---VASLSHTTSFMMILRTVTPEDKSFAVGIQFMLFRVLAFLPSPVLYGTAIDTA 569

  Fly   605 CLVWGKTCSNKGNCWLYDTKSMRYALNLSAAFFIFLGGFL 644
            ||||||.||...:|..|:....|:.. |....|...|||:
Zfish   570 CLVWGKKCSKSTSCLYYNLDLFRHRF-LGLQIFFICGGFV 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	170/596 (29%)
		MFS	69..>425	CDD:119392	99/387 (26%)
		KAZAL_SLC21	462..514	CDD:238650	22/54 (41%)
slco2b1	NP_001032767.2	OATP	27..591	CDD:308646	170/596 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578745
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850