Protein Alignment Oatp58Da and slco1f4

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001074135.2
• Gene: slco1f4 / 791184
• ZFINID: ZDB-GENE-070112-2172
• Length: 644
• Species: Danio rerio
• Alignment Length: 597
• Identity: 179/597 - (29%)
• Similarity: 290/597 - (48%)
• Gaps: 62/597 - (10%)

  Fly    80 TMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVA 144
            :||.:|...|||.:|||::||:...|.|....::..||...::.|.....|||:.:|.|:|.:..
Zfish    41 SMTGSYTKSTITQIEKRFEIPSSTVGFIDGSFEMGNMLVITLVSYIGAKFHRPKIIGAGVLLMGI 105

  Fly   145 FCLLTSSLHFLYGAGE--DALQLTREFGQVNETLTNQERDKKLCQPTAGGCVQEEV---GLWVPQ 204
            ..||.:|.|||.|..:  .|...|.:.|......|.....::..|....||.:||.   ..|
Zfish   106 GTLLMASPHFLMGRYKYGTAATHTNDAGNFTVISTCSSDSQETLQQPFSGCQKEEAESSPFW--- 167

  Fly   205 VFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIE 269
            |.:.....:.|:|:|....||::::||......:...:.....|:.:||..||.|.::|..||::
Zfish   168 VIVVLGNTMRGIGEASIVPLGMSFIDDYARPENSAFYIGCLNTLKGIGPIFGYMLGSLCANLYVD 232

  Fly   270 --------PTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKRRLQLKQDE 326
                    .|:.|    :|.||:||||||::|...:||::|...:..||.||...:..|.....:
Zfish   233 FGLVDQESVTITP----QDSRWVGAWWLGYVVSGLLTLLAAFPFWFLPKVLPENSQISLLDNTPQ 293

  Fly   327 RKQSLPLNERSLADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMAT 391
            :.::.|.....:.|...|.|:|..||:|:.....||:.|..:.:...:||||:|.|:.|||:.|.
Zfish   294 QHKTTPSLTEIVKDFAPTFKRLLTNKIYILYLAYSIVAFNDFAIVATYTPKYLEQQFGQSASKAN 358

  Fly   392 MATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVAIGCE--------- 447
            ...|..::...|.|:.:||.::.::|....|.|..|.:....||...:.:.|:.||
Zfish   359 FLIGVTSIPAVALGVFLSGLMMKRFKWGLLASARVNLLTIVATVFLAVPFFALSCENLDIAGVTV 423

  Fly   448 ---GSDRLNTLTTLSAGNSCSASCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYTG 509
               ||..:..:|: ....||:|.|.|..:.:.|||..:.:|:||.|||||:. |:.|.....:..
Zfish   424 PYQGSTEVQGVTS-DVLPSCNADCGCPDLQWDPVCGENGVTYISPCHAGCNS-TQGAGRNMTFHD 486

  Fly   510 CECLGSSSLNSEPESQFAVDGTCPVD--CFNEFLIFLGV------MCFLKLVGASSKSTNLLLAL 566
            |.|:.|..|:....|  ||.|.|..|  |.....|:||:      :|.|.::      ....::|
Zfish   487 CRCIQSWGLSVGNSS--AVLGQCSRDPKCNRMIYIYLGLQSLAFFLCGLGII------PFFTMSL 543

  Fly   567 RCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWG--KTCSNKGNCWLYDTKSMRYA 629
            |.:.|:.|:.::|:..:|..:||.||:||:||.|||:.||.||  |:| .:|.|.:||.::.|
Zfish   544 RIVDPELKSLSVGMLLLAVRVLGGIPAPIYFGALIDSTCLKWGQNKSC-GRGACRIYDIETFR-- 605

  Fly   630 LNLSAAFFIFLG 641
                   |:|.|
Zfish   606 -------FLFQG 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	175/580 (30%)
slco1f4	NP_001074135.2	MFS	26..544	CDD:475125	148/519 (29%)