Protein Alignment Oatp58Da and Slco6c1

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_083218.1
• Gene: Slco6c1 / 74441
• MGIID: 1921691
• Length: 706
• Species: Mus musculus
• Alignment Length: 748
• Identity: 167/748 - (22%)
• Similarity: 286/748 - (38%)
• Gaps: 144/748 - (19%)

  Fly     7 KVDLEKSE------------TLPFIEKPFAISDKERESAPENETEGED----GGKDTYCGFWIFK 55
            |.|..|||            |:|..:|.||...|.::|....|....|    ..|:...|.....
Mouse    19 KEDTNKSESEGVTKLQTYLKTIPIAKKKFAKLPKRKKSPTSAELLLIDPRYSASKEGPLGLGPIV 83

  Fly    56 GPSMQRFATEHMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAA 120
            .|.:|||.....::.||..|..:....||..:.|:...:.::.:......::...:.|::.:.|.
Mouse    84 LPFVQRFNNIDGFMTLYVAAVLIHGALFAVVDMTLNIYQVQFSLTRTEWYLMDFSDYIASFVVAI 148

  Fly   121 ILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYG----------AGEDALQLTREFGQVNET 175
            |:.::....:|.||       |.|.|:|......|:.          .|..:::|..|
Mouse   149 IIAHFGSKGNRTRW-------IAASCILMGLESMLFAFPFFTYEIIIPGRQSIELCME------- 199

  Fly   176 LTNQERDKK--LC---QPTAGGCVQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDN--T 233
                |.:|:  :|   .|....|:          .|..|.|.|.|:.....|.|||.::.|:  |
Mouse   200 ----ENEKRNIICGNSVPNRSKCI----------YFHIAGQCIHGIAGMPIYILGITFIFDHIPT 250

  Fly   234 SKAKTPAMLSMSTFLRMLGPAIGYSLAAV-CLRLYIEPTLEPLIGQEDPR----WLGAWWLGWLV 293
            |.......:..|.:|      |||.|..| .|:.:..|..|..:..|..:    ....||..:|:
Mouse   251 SSCGFYLAIGHSAYL------IGYLLGMVGGLQNFQPPPKEKTVEIEPAKVYQLLQSGWWKTFLI 309

  Fly   294 LAAITLVSAILLFMFPKQLPSARKRRLQLKQDERKQSLPLNERSLADM---------MKTVKKLS 349
            :|||:...:.::..||..||.|.|.||.    :||:. |..:|.|.||         :..:..:.
Mouse   310 IAAISFCVSFMMVCFPTSLPGAHKLRLA----KRKEP-PTIDRRLKDMKIQPHLKGFLHNIWHIL 369

  Fly   350 KNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVIS 414
            ||.:.:...:..:..:..:.....|.|.:::||:..:..:|::.||...|.....|..:.|.::.
Mouse   370 KNPLMLTQAICKVSEYLTFNTSLYFLPHHLQTQFLITPGIASLLTGAFVLPGGIIGHFLGGLIVD 434

  Fly   415 KYKPSARAMAAWNAIVDFVTVAGILCYVAIGC------------EGSDRLNTLTTLSAGNSCSAS 467
            :.:.:.:....:..:...|:|...|....:.|            :|..:|..||.     .|:..
Mouse   435 RLEMTNKNKLKFTLVTTVVSVGLFLLIFFVECQTTTFAGINEDYDGYGQLGNLTA-----DCNEY 494

  Fly   468 CHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQF--AVDG 530
            |.|....|..:|..|...:.|.|.||| :.||.:.....|..|.|:......|:.|.||  |:.|
Mouse   495 CDCTTSLYTSICGRDEKEYFSPCFAGC-KATKVSQTEKTYYNCSCIKEGLAASDDEGQFIDAIAG 558

  Fly   531 TCPVDCFNEFLIF--------LGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASL 587
            ||..||....|.|        ...||.:.::.         :.|:.:|.:..:.:||:.......
Mouse   559 TCDSDCLKLPLFFAFYFSATVFSNMCSIPVIS---------IILQSVPANFTSLSLGVTYAIVKF 614

  Fly   588 LGFIPSPIFFGWLIDNYCLVW-GKTCSNKGNCWLYDTKSMRY---ALNLSAAFFIFLGGFLNIAV 648
            :..:|:|:.|.......|:.| ...|..|..||:|:...:.|   .:.:|:...|.|   |||..
Mouse   615 VASVPAPLLFRLSSAIACIYWDNNRCGGKERCWIYNKNILVYEFMGIWMSSQLIIVL---LNIYA 676

  Fly   649 WYHAKNLKIFD--------EEESSPKDSLKNKE 673
                  ::|.|        |.:::.||..:.||
Mouse   677 ------IQIHDVVVHGEITESKTTVKDVKEQKE 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	133/612 (22%)
Slco6c1	NP_083218.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		2/4 (50%)
		MFS_SLCO6_OATP6	93..594	CDD:340963	119/554 (21%)