Protein Alignment Oatp58Da and Slco6d1

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_011246380.1
• Gene: Slco6d1 / 70866
• MGIID: 1918116
• Length: 729
• Species: Mus musculus
• Alignment Length: 715
• Identity: 161/715 - (22%)
• Similarity: 285/715 - (39%)
• Gaps: 137/715 - (19%)

  Fly     1 MTEERGKVDLEKSE----TLPFIEKPFAISDKERESAPENETEGEDGGKDTY-CGFWIFKGPSMQ 60
            |.|.:...:..|.|    |||...|.||.:...::|    :.:.:|..::.| .|..:|  |.:|
Mouse    20 MDEHQKTKEPRKLEMFLVTLPTAVKKFADTPDMKKS----DRKYKDPSEEPYGLGSLVF--PCLQ 78

  Fly    61 RFATEHMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKI---PTKVSG-IISVGNDISTMLTAAI 121
            ||.....::.|..||....:|.||..:.:|    |.|..   |:::.. ::...::....|.:..
Mouse    79 RFNNVKSFLTLSFLAVVAHSMIFALVDQSI----KLYVAQLSPSRIEEYLMDTSDNFVAFLFSMF 139

  Fly   122 LGYYAGHRHRPRWMGIG--LLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQERDKK 184
            :.::.|..:|..|:..|  |..|.|.......|:|      :.::|:    .|.|.|..:.:..|
Mouse   140 VAHFGGRGNRANWVAAGCFLTGIAAIVFAVPFLNF------EIIKLS----VVKEELCEEGKLPK 194

  Fly   185 LCQPTAGGCVQEEVGLWVPQ----VFLFA-AQLISGVGQALFYTLGIAYMDD----NTSK---AK 237
            :|:||.           :|.    :|:|. .|.:.|:.....|.|..:::.|    |:|.   |.
Mouse   195 VCEPTV-----------LPHKSICIFIFIFGQCLHGIAGLPLYILATSFIFDHVPTNSSGLYIAL 248

  Fly   238 TPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEPTLEPLIGQEDPRWL-GAWWLGWLVLAAITLVS 301
            ..|.|.:...|..:|..:.:.::|       :..::.:..::..|.| ..||..::.:|.....:
Mouse   249 VDAALGVGYCLGFIGGMLNFKMSA-------QEVMQAVGHRQRIRILQRGWWRTFIFVAVFAFCT 306

  Fly   302 AILLFMFPKQLPSARKRRLQLKQDE-------RKQSLPLNERSL--------------------- 338
            .:.|..||..||.||:.||:..|:.       :.:.:..|.:|:
Mouse   307 TLPLLGFPSSLPGARQIRLEKSQEPPTFDRRLKNKEIKNNLKSVLHATWIYHRGHLTILSQTCST 371

  Fly   339 ---------------ADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAA 388
                           .|:.|..:.|.:|.:.:...:.....|..:....:|.|:|::|::....:
Mouse   372 SLGGICCSTTGKAIDGDLQKLTQCLIRNPLVLSQVVCKFTEFTTFKSSAVFLPQYLQTRFLIRPS 436

  Fly   389 MATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVAIGCEGS---- 449
            .|:|.||...|..|..|....|:::.:.:.:.:....:..:..||::...|....:.||.|
Mouse   437 SASMLTGVFILPGSIFGHFFGGFIVHRMQMNNKNKLKFLVVASFVSIVLFLLTFFVECEISKFAG 501

  Fly   450 -----DRLNTLTTLSAGNSCSASCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYTG 509
                 |||..:..|:|  .|:..|.|....|.|||..|...:.|.|.||| :.||.......|..
Mouse   502 INDDYDRLGIIGNLTA--PCNVPCGCTTSEYNPVCGRDETQYFSPCFAGC-KATKKLRKEKTYYN 563

  Fly   510 CECLGSSSLNSEPESQF--AVDGTCPVDC-----FNEFLI---FLGVMCFLKLVGASSKSTNLLL 564
            |.|:......::.|.|:  ||.|||...|     |..|..   ||...|.:         .:.|:
Mouse   564 CSCIKEGLTTADNEGQYIDAVSGTCNTRCLTLPLFFAFYFTATFLSSFCSI---------PSALI 619

  Fly   565 ALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWG-KTCSNKGNCWLYDTKSMRY 628
            .::.:|....:.:|||.|......|.:|:||.|....|..|..|| ..|..|..||:|:|:::.|
Mouse   620 VIQSVPTSWNSMSLGLMSTVWRFTGSVPAPILFAATSDFTCQFWGINECGEKVRCWIYNTENLVY 684

  Fly   629  628
            Mouse   685  684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	141/640 (22%)
		MFS	69..>425	CDD:119392	78/417 (19%)
		KAZAL_SLC21	462..514	CDD:238650	18/51 (35%)
Slco6d1	XP_011246380.1	MFS	83..622	CDD:391944	121/582 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810