Protein Alignment Oatp58Da and slco1b3

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_031753845.1
• Gene: slco1b3 / 613085
• XenbaseID: XB-GENE-5943217
• Length: 690
• Species: Xenopus tropicalis
• Alignment Length: 670
• Identity: 193/670 - (28%)
• Similarity: 307/670 - (45%)
• Gaps: 91/670 - (13%)

  Fly    26 SDKERESAPENETEGEDGGKDTYCGFWIFKGPSMQRFATEHMYVILYGLAGCVMTMTF--AYFNG 88
            ||....:....|....:||.:|         |..:.....::.:.|..|........|  :|...
 Frog     8 SDSNNPNMDPPEVLMSNGGGET---------PPQKVSCCSNLKMFLVALCFSYFAKAFSGSYMKS 63

  Fly    89 TITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLH 153
            :||.:|:|:.|.:...|:|....:|..::..||:.|:....||||.:..|.:.:.....||:..|
 Frog    64 SITQIERRFDISSSTVGMIDGSFEIGNLMVIAIVSYFGAQFHRPRIIAAGCILMSLGSFLTAMPH 128

  Fly   154 FLYG-------AGEDALQLTREFGQVNETLTNQERDKKLCQPTAGGCVQEEVG-LWVPQVFLFAA 210
            |..|       .|..:|...... .|:..|.|    :.|.......||.|... :|   |||...
 Frog   129 FFMGLYKYETVGGPTSLNSNATI-NVSPCLAN----RSLVDTPKPDCVTENGSHMW---VFLLVG 185

  Fly   211 QLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIE------ 269
            .::.|:|:.....|||:|:||.:....||..::....:.|.||..|:.|.:...|||::
 Frog   186 NILRGIGETPIAPLGISYLDDFSRPENTPLHIACLHTVAMFGPMTGFMLGSFLARLYVDIGFVDT 250

  Fly   270 --PTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARK--RRLQLKQDERKQS 330
              .|:.|    :|.||:||||:|:|:..|:.|:|||..|..|:.|...::  ::.|.||.|.|..
 Frog   251 DTITITP----QDTRWVGAWWIGFLLSGAVNLMSAIPFFFLPESLKEEQREGQKPQTKQGEEKGH 311

  Fly   331 LPLNERSLADMMKTVKKLSKNKVYVYNTMASILY---FFGYMVYWIFTPKYIETQYRQSAAMATM 392
            ....:.:|......:|.|..|:::|.....::|.   |.|::.|   .|||:|.||.||.:.|..
 Frog   312 KQKEKPTLRGFFAALKTLCFNRLFVMLMCLTLLQTNSFLGFITY---KPKYMEQQYGQSISKANF 373

  Fly   393 ATGTVALGFSAAGILISGYVISKYK---PSARAMAAWNAIVDFVTVAGILCYVAIGCEGSD---- 450
            .||...|..:|.|:.:.|.::.:||   ..|..||...:::.|:.   .|....||||.::
 Frog   374 VTGVSTLPAAALGMFLGGLIMKRYKFGLLGASKMAYGTSLLAFLL---SLSAFFIGCENNNVAGI 435

  Fly   451 -------RLNTLTTLSAGNSCSASCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYT 508
                   ::|........:.|::.|||....:.|||..:.:|::|||.|||...|...|| |:|.
 Frog   436 TVTYDRVKVNNFQDRIIYSPCNSDCHCSSKQWDPVCGENGVTYVSACLAGCKASTGSGLG-TVYH 499

  Fly   509 GCECLG---SSSLNSEPESQFAVDGTCP--VDCFNEFLIFL---GVMCFLKLVGASSKSTNLLLA 565
            .|.|:.   |:::||.     |..|:||  .||...|:.::   .:..|:..:||||....||.:
 Frog   500 NCSCIDTALSTAVNSS-----AHLGSCPRGPDCSRMFMFYVVTQAINTFIFALGASSAYVLLLWS 559

  Fly   566 LRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWG-KTCSNKGNCWLYDTKSMRYA 629
            :.   |:.|:.|:|:..:....|..||:||:||.:||..||.|| :.|..:|.|.|||..|.|..
 Frog   560 VN---PEMKSLAVGVYMLLIRTLAGIPAPIYFGAIIDKSCLKWGTRLCGGRGACRLYDADSFRRR 621

  Fly   630 -LNLSAA--------FFIFL 640
             |.|:|.        ||||:
 Frog   622 FLGLTAGIRAPSYILFFIFI 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	177/604 (29%)
		MFS	69..>425	CDD:119392	108/381 (28%)
		KAZAL_SLC21	462..514	CDD:238650	21/51 (41%)
slco1b3	XP_031753845.1	MFS_SLCO1B_OATP1B	40..558	CDD:341015	153/541 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010