Protein Alignment Oatp58Da and slco3a1b

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_699020.3
• Gene: slco3a1b / 570448
• ZFINID: ZDB-GENE-161017-34
• Length: 690
• Species: Danio rerio
• Alignment Length: 667
• Identity: 186/667 - (27%)
• Similarity: 305/667 - (45%)
• Gaps: 95/667 - (14%)

  Fly    32 SAPENETEGEDGGKDTYC--GFWIFKGPSMQRFATEHMYVILYGLAGCVMTMTFAYFNGTITTLE 94
            |.|  :||.::..|.|.|  ...||       ..:|...::..|..|       ||....:||||
Zfish     6 STP--DTEPDECQKKTSCFSNIKIF-------LISECALMLAQGTVG-------AYLVSVLTTLE 54

  Fly    95 KRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFL---- 155
            :|:.:.:...|:|:...:|..:.....:.|:....||||.:|.|.:.:....||::...||
Zfish    55 RRFNLQSADVGVIASSFEIGNLALILFVSYFGARAHRPRLIGCGGIVMALGALLSALPEFLTHQY 119

  Fly   156 -YGAGEDALQLTREFGQVNETLTNQERDKKLCQPTAGGCVQEEVGLWVPQVFLFAAQLISGVGQA 219
             |..||     :|..||.....:|..| ..|..|  |..........:..:.|..||::.|||..
Zfish   120 QYQTGE-----SRPVGQGQNVCSNSSR-AGLSDP--GYICGNRTNTNMMYLLLIGAQMLLGVGAT 176

  Fly   220 LFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIE------PTLEPLIGQ 278
            ....||::|:||:..:..:...:.:.....:.|||.|:.|.::|.::|::      .||:  |..
Zfish   177 PLQPLGVSYIDDHVRREDSSLYIGILFSTLVFGPACGFILGSLCTKVYVDAVFIDTTTLD--ITP 239

  Fly   279 EDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQL------PSARKRRLQLKQD--------ERKQ 329
            :||||:||||.|:::......||:..:|.||:.|      |.....:..|..:        :...
Zfish   240 DDPRWIGAWWGGFIICGLFLFVSSFFMFGFPQSLNEPGEGPGGESEQAMLPAELVQEYEGVKTSD 304

  Fly   330 SLPLNE-----RSLADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAM 389
            .|.::.     :.|..:.|..|.|..|.|:....:|:.:.......:..|..||:|.|:..|.:.
Zfish   305 DLEISTGLTCCQHLQVIPKVTKHLLSNPVFTCVILAACMEIAVVAGFAAFLGKYLEQQFNLSTSS 369

  Fly   390 ATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVA---IGCE---- 447
            |....|..|:..:..||.:.|.::.|...||........||:.::.|   |||:   :||:
Zfish   370 ANQLLGMTAIPCACLGIFLGGLLVKKLDLSALGAIRLAMIVNIISTA---CYVSFLFLGCDTGPV 431

  Fly   448 -------GSDRLNTLTTLSAGNSCSASCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRT 505
                   |::.|.:.....|  :|.:.|:|.....:|||.::.:|::|||.|||:        ||
Zfish   432 AGVTVAYGNESLGSWERTEA--ACLSGCNCYKSSLSPVCGSNGVTYLSACLAGCT--------RT 486

  Fly   506 IYTGCECLG-SSSLNSEPESQFAVDGTCP-VDCFNEFLIFLGVMCFLKLVGASSKSTNLLLALRC 568
            ..|||:|:. |..|.:      |..|.|| ..|...||.||.|:|...::||.:::.::::.:|.
Zfish   487 NLTGCKCIAHSEGLGT------ATPGKCPSPGCQQAFLTFLAVVCACSMIGAMAQTPSVIILIRT 545

  Fly   569 MPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCSNKGNCWLYDTKSMRYALNLS 633
            :.|:.|::|||:..:...||||||.|:.||..||:.||:|...|..||.|.|||..:.|| |.:|
Zfish   546 VSPELKSYALGVLFLLLRLLGFIPPPLIFGIGIDSTCLLWSSMCGIKGACMLYDNVTYRY-LYVS 609

  Fly   634 AAFFIFLGGFLNIAV-W 649
            .|..:....|:..|| |
Zfish   610 IAIVLKSSAFILYAVTW 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	167/604 (28%)
slco3a1b	XP_699020.3	MFS	25..544	CDD:475125	143/561 (25%)