Protein Alignment Oatp58Da and slco5a1a

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_073776477.1
• Gene: slco5a1a / 570033
• ZFINID: ZDB-GENE-090316-1
• Length: 819
• Species: Danio rerio
• Alignment Length: 757
• Identity: 216/757 - (28%)
• Similarity: 337/757 - (44%)
• Gaps: 138/757 - (18%)

  Fly    12 KSETLPFI---EKPFAISDKERESAPEN--------ETEGEDGGKDTYCGFWIFKGP--SMQRF- 62
            ||::||.:   :.|...:|:....||.:        .||..:..     |...|:.|  .::|:
Zfish    32 KSKSLPVLSESQTPERDADQTLLPAPHSSARCGSPVRTESREPE-----GVLRFRLPRLPLRRYV 91

  Fly    63 ----ATEHMYVILYGLAGCVMTMTF-------AYFNGTITTLEKRYKIPTKVSGIISVGNDISTM 116
                |....::.      |:..:||       .|.:..|||:||||.:.:..||::....||.::
Zfish    92 DGILADSRCFLF------CMCYLTFIQSLMVSGYLSSVITTIEKRYSLRSSESGLLVSCFDIGSL 150

  Fly   117 LTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQER 181
            :....:.|:.|...||||:.:|.:.|.....|.|..||:    ....||.    ::|.|:..:
Zfish   151 IVVVFISYFGGRGQRPRWLAVGGVFIAVGAALFSLPHFI----SPPYQLE----ELNSTVGGE-- 205

  Fly   182 DKKLC-------------QPTAGGCVQE----EVGLWVPQVFLFAAQLISGVGQALFYTLGIAYM 229
              .||             :||...|.:|    |..|:|  .....||::.|:|....||||..|:
Zfish   206 --GLCAGASASANASGQEKPTLSRCQREQEESEHALYV--ALFICAQILVGMGSTPIYTLGPTYL 266

  Fly   230 DDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEPTLEPLIGQEDPRWLGAWWLGWLVL 294
            |||..|......|::...:..||||.||.|..:.:..|::|.....|.|.|||::|.||.|:|:.
Zfish   267 DDNVKKENASLYLAIMYVMGALGPAAGYLLGGILIGFYVDPGTVVNIDQGDPRFVGNWWSGFLLC 331

  Fly   295 AAITLVSAILLFMFPKQLPSARKR-RLQLKQ---DERKQSLPLNERSLA-----DMMKTVKKLSK 350
            |...|:....:|.|||:||..:|: :..:|:   |.......:.|:|.|     ...|.:|.|.|
Zfish   332 AVAMLLVIFPMFSFPKKLPPRQKKSKRGVKKGAGDVSSDDEMMKEKSQAVSSSMGFGKNIKDLPK 396

  Fly   351 NKVYVYNTMASILYFFGY-------MVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILI 408
            ..|.:.:.:..:.....|       ..:..|.||:||:|:...|:.|::.||.:.:..:..||.:
Zfish   397 AAVRILSNVTFLFVSLSYTAECAIVTAFITFIPKFIESQFGVPASSASIYTGLIIVPSAGVGIFL 461

  Fly   409 SGYVISKYKPSARAMAAWNAIVDFVTVAGILCY---VAIGCE----GSDRLNTLT----TLSAGN 462
            .||:|.|.|..||..|....|...|:   :||:   ..:|||    |...:...|    |||..|
Zfish   462 GGYIIKKLKLGAREAAKLAMICSGVS---LLCFSTLFIVGCESINLGGINIPYTTGPTLTLSHRN 523

  Fly   463 ---SCSASCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYTGCECLGS------SSL 518
               ||:.:|.|....|||||.:|.||:.:.|.||||.......|...|:.|.|:.|      |..
Zfish   524 LTGSCNVNCGCKIHEYAPVCGSDGITYFNPCLAGCSNIANHTSGIRNYSDCACVQSRQVITPSGG 588

  Fly   519 NSE----------PESQFAVDGTCPVDC--FNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPP 571
            |.|          .|:.||:.|.|...|  ...|||||.:   :.|:.|.::.:.:::.||.:..
Zfish   589 NHELQLVIVKTYLNENGFALAGKCERTCGTLITFLIFLFI---VTLITACAQPSVIIVTLRSVDE 650

  Fly   572 DEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCSNKGNCWLYDTKSMRYALNLSAAF 636
            :::.||||:..:....|.:||:||:||.:||..|::|.:.|...|:||.||..|:|:.....||.
Zfish   651 EDRPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQDCGFHGSCWEYDVTSLRFVYFGLAAS 715

  Fly   637 FIFLGGFLNIAVWYHAKNLKIFDEEESSPKDSLKNKEVEMKT 678
            ..|||.......||                 |||.:|.:..|
Zfish   716 LKFLGFLFIFLTWY-----------------SLKRREEQTHT 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	187/630 (30%)
slco5a1a	XP_073776477.1	None