Protein Alignment Oatp58Da and slco1c1

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_005164528.1
• Gene: slco1c1 / 562772
• ZFINID: ZDB-GENE-041210-50
• Length: 710
• Species: Danio rerio
• Alignment Length: 679
• Identity: 191/679 - (28%)
• Similarity: 310/679 - (45%)
• Gaps: 92/679 - (13%)

  Fly    28 KERESAPENETEGEDGGKDTYCGFWIFKGPSMQRFATEH-------------MYVILYGLAGCVM 79
            ||..|..|||           ...|....|:.:|.:.|:             |:::....|....
Zfish     7 KESSSPKENE-----------IFLWRMDLPNKERRSPENSPSSSRRCCSSFKMFLVALSFAYFSK 60

  Fly    80 TMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVA 144
            .::.:|...|||.||:|:.||:.:.|:|....:|..:|..|.:.|:....|||:.:.||.|.:..
Zfish    61 ALSGSYMKSTITQLERRFDIPSYLIGVIDGSFEIGNLLVIAFVSYFGAKLHRPKIIAIGCLLMSL 125

  Fly   145 FCLLTSSLHFLYG--AGEDALQLTREFGQVNETLTNQERDKKLCQPTAG-----GCVQE-EVGLW 201
            ...|.:..||:.|  ..|.:::|:     ||.:.:.........:|:..     ||..| .:.:|
Zfish   126 GTFLIALPHFIIGRYKFETSIRLS-----VNSSSSLSPCSLSSAEPSTSSVPSTGCEHESRLSMW 185

  Fly   202 VPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRL 266
               :::|...::.|:|:.....|||:|:||:..:......:.....:.::||..||.|.:||.::
Zfish   186 ---IYVFLGNILRGIGETPVQPLGISYIDDHALEENAAFYIGCVQTISVIGPVFGYLLGSVCAKI 247

  Fly   267 YIE---PTLEPL-IGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKRRLQLKQDER 327
            |::   ..:|.: |...|.||:||||||:|:...|||:||:..:..||.|| ..:|||.....||
Zfish   248 YVDIGFVNMESISITPGDARWVGAWWLGYLIAGFITLLSAVPFWFLPKSLP-LPERRLSKYSPER 311

  Fly   328 KQSL--------------PLNERSLA-DMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPK 377
            ...:              |.|...:| |.:.|::.|..|.||......:|:.|...:....:.||
Zfish   312 NSFIKDSALLEHKYQADEPANFLEMAKDFLPTLRSLLGNPVYFLYLCVTIIQFNSLIGMVTYKPK 376

  Fly   378 YIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYV 442
            |||..|.|||:.|....|.:.:...|.|:...|.::.|:|.|....|.:......:.....|.:.
Zfish   377 YIEQHYGQSASKANFLMGVINIPAVALGMFSGGVIMKKFKLSIMGAAKFALGTSLLGYFLSLFFF 441

  Fly   443 AIGCE------------GSDRLNTLTTLSAGNSCSASCHCDYVHYAPVCSADNITFISACHAGCS 495
            ::|||            |::.| .:...|...||:|:|||...::.|||..|.:|::|.|.|||
Zfish   442 SMGCENASVAGITMSYNGTESL-FMADGSLRASCNAACHCPEKNWDPVCGEDGLTYVSPCLAGC- 504

  Fly   496 ERTKDALGR-TIYTGCECLGSSSLNSEPESQFAVDGTC--PVDCFNEFLIFLGVMCFLKLVGASS 557
             ||....|. |::..|.|:|..       :|.|..|.|  ...|...|..||.:......:.:..
Zfish   505 -RTSHGSGMDTVFEQCSCIGVG-------NQTATAGQCNNRESCHRIFPYFLALSVITSFIISLG 561

  Fly   558 KSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWG-KTCSNKGNCWLY 621
            .:...:|.:||:.|..|:.|||..::....|..||:||:||.:||..||.|| |.|..:|.|.:|
Zfish   562 GTPGYMLLIRCIKPQLKSLALGFHTLTTRTLAGIPAPIYFGAIIDTTCLKWGHKKCGGRGACRIY 626

  Fly   622 DTKSMRYA-----LNL-SAAFFIFLGGFL 644
            :|.:.|.|     |.| :.:||:.:.|.|
Zfish   627 NTAAYRIAYLGLTLGLRTVSFFLCILGLL 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	173/601 (29%)
slco1c1	XP_005164528.1	MFS_SLCO1C_OATP1C	46..572	CDD:341017	147/544 (27%)