Protein Alignment Oatp58Da and SLCO1C1

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001139418.1
• Gene: SLCO1C1 / 53919
• HGNCID: 13819
• Length: 730
• Species: Homo sapiens
• Alignment Length: 637
• Identity: 176/637 - (27%)
• Similarity: 288/637 - (45%)
• Gaps: 124/637 - (19%)

  Fly    77 CVMTMTF-------AYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPR- 133
            |.::..:       .|...|||.:|:|:.||:.:.|:|....:|..:|....:.|:....|||:
Human    47 CALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKI 111

  Fly   134 ------WMGIGLLTI------------------------VAFCLLTSSLHFLYGAGEDALQLTRE 168
                  .||:|.|.|                        ::.|||.||
Human   112 IGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESS----------------- 159

  Fly   169 FGQVNETLTNQERDKKLCQPTAGGC-VQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDN 232
             .|:..::..:.:.|     .:..| |.....:|   :::|...|:.|:|:.....|||||:||.
Human   160 -SQLPVSVMEKSKSK-----ISNECEVDTSSSMW---IYVFLGNLLRGIGETPIQPLGIAYLDDF 215

  Fly   233 TSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIE--------PTLEPLIGQEDPRWLGAWWL 289
            .|:......:.....:.::||..|:.|.::|.:||::        .|:.|    :||:|:|||||
Human   216 ASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITP----KDPQWVGAWWL 276

  Fly   290 GWLVLAAITLVSAILLFMFPKQLPSARKRRLQLKQDERKQSL---------PLNERS-----LAD 340
            |:|:...|:|::|:..:..||.||.::.|.......|:.:.:         |..|.:     ..|
Human   277 GYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARD 341

  Fly   341 MMKTVKKLSKNKVYVYNTMASILYF---FGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFS 402
            .:.::|.|..|.||......|.:.|   ||.:.|   .|||||.||.||::.|....|.:.:...
Human   342 FLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTY---KPKYIEQQYGQSSSRANFVIGLINIPAV 403

  Fly   403 AAGILISGYVISKYKPS---ARAMAAWNAIVDFVTVAGILCYVAIGCEGSDRLNTLTTLSAG--- 461
            |.||...|.|:.|::.|   |..:...:::..::.   .|...|:|||.|| :..||....|
Human   404 ALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLL---FLSLFALGCENSD-VAGLTVSYQGTKP 464

  Fly   462 ---------NSCSASCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRT-IYTGCECLGSS 516
                     :.|::.|.|....:.|:|..:.||::|||.|||  :|.:..|:. |:..|.|:|.:
Human   465 VSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGC--QTSNRSGKNIIFYNCTCVGIA 527

  Fly   517 SLNSEPESQFAVDGTCPVD--CFNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALG 579
            :..|...|  .:.|.|..|  |...||.||.:........:.......:|.|||:.|..|:||||
Human   528 ASKSGNSS--GIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALG 590

  Fly   580 LGSMAASLLGFIPSPIFFGWLIDNYCLVWG-KTCSNKGNCWLYDTKSMRYAL 630
            :.::|..:|..||:|::||.|||..||.|| |.|.::|:|.|||:...||.:
Human   591 IYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQI 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	174/631 (28%)
		MFS	69..>425	CDD:119392	104/414 (25%)
		KAZAL_SLC21	462..514	CDD:238650	18/52 (35%)
SLCO1C1	NP_001139418.1	MFS_SLCO1C_OATP1C	42..579	CDD:341017	145/572 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820