Protein Alignment Oatp58Da and Slco1a7

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001365611.1
• Gene: Slco1a7 / 435927
• MGIID: 3643685
• Length: 670
• Species: Mus musculus
• Alignment Length: 662
• Identity: 179/662 - (27%)
• Similarity: 300/662 - (45%)
• Gaps: 69/662 - (10%)

  Fly    69 VILYGLAG-CV-MTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHR 131
            |.|..|.| || .::|.::....:..:|:::.:.|...|:|:....:..:|....:.|:....||
Mouse    21 VFLLALTGACVSKSLTGSHMKSMLLQIERQFGLLTSTVGLITGSFSMGMLLVIIPVSYFGTKLHR 85

  Fly   132 PRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQERDKKLCQPT--AGGCV 194
            |..:|:|.:.:...|.:.|..|||.|..|....::......:.:....|......:||  ...|.
Mouse    86 PIMIGVGCMFMGLGCFIISLPHFLMGRYEYETTISPTSNLSSNSFLCMENRSLTLKPTQDTTECG 150

  Fly   195 QEEVGL-WVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYS 258
            :|...| |   :::....:|.|:|:.....|||:|::|......:|..:.:......:...||||
Mouse   151 REIKSLMW---IYVLVGNIIRGMGETAIMPLGISYIEDFAKSENSPLYIGILEIGITISYWIGYS 212

  Fly   259 LAAVCLRLYIEP----TLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKRR 319
            |.:.|..:|::.    |.:..|...|.||:||||:|:||.|.:..:::|..|.|||.||   |..
Mouse   213 LGSFCANIYVDTDSGNTDDLTITPTDTRWVGAWWIGFLVCAGVNFLTSIPFFFFPKTLP---KEG 274

  Fly   320 LQ---------LKQDERKQSLPLNERSLADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFT 375
            ||         .::..|:::...|:|.:.|....:|.||.|.:|:...:.|:|.|..::....:.
Mouse   275 LQDNGDGTENAKEEKHREKAKKENQRIIKDFFPLMKNLSCNPIYMLYLLISVLQFNTFVSMVSYV 339

  Fly   376 PKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNA----IVDFVTVA 436
            |||:|.||.:|:|......|...|.....|.|:.|.::.|:|.:|: .||:.|    :.|::.
Mouse   340 PKYLEQQYGKSSADVLFIMGIYMLPPICLGYLLGGLIMKKFKITAK-KAAYIAFCLSLTDYLL-- 401

  Fly   437 GILCYVAIGCEGSDRLNTLTTLSAG------------NSCSASCHCDYVHYAPVCSADNITFISA 489
             .|......|: |.::..||....|            ..|:..|.|....:.|||..:.:.::||
Mouse   402 -SLSNYMTNCD-SFQVAGLTASYEGVQHPLHVDHEVLADCNTRCSCLTNTWDPVCGNNGLAYMSA 464

  Fly   490 CHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQFAVDGTC---PVDCFNEFLIFLGVMCFLK 551
            |.|||.:...:.: ..::..|.|:.||..:|      ||.|.|   | ||.|....|:.:.....
Mouse   465 CLAGCEKSVGNGI-NMVFQNCSCIRSSGNSS------AVLGLCNKGP-DCDNMLKYFIIIFSVKM 521

  Fly   552 LVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGK-TCSNK 615
            .:.:.|.....::.||||.|:||:..:||.:....:...||:||:||.|||..||.||. .|..|
Mouse   522 FIFSLSSIPGYMVLLRCMKPEEKSLGVGLHTFCTKIFAGIPAPIYFGALIDRACLHWGTLKCGEK 586

  Fly   616 GNCWLYDTKSMRYA-LNLSAAFFIFLGGFLNIAVWYHAKNLKIFD--EEESSP-----KDSLKNK 672
            ..|.:||..|.||. ..|.||    |.|...:...:..:.::.|.  |:..||     :..|..|
Mouse   587 AACRIYDINSFRYLFFGLPAA----LTGSSYLPAVFLLRLMRTFQLPEDTDSPDTELAETKLIEK 647

  Fly   673 EVEMKTIDSNPE 684
            |.:...:..:|:
Mouse   648 ENDCTDVHRSPK 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	163/594 (27%)
Slco1a7	NP_001365611.1	oat	1..624	CDD:273279	171/625 (27%)