Protein Alignment Oatp58Da and Slco6d1

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_017452073.1
• Gene: Slco6d1 / 367321
• RGDID: 1359388
• Length: 723
• Species: Rattus norvegicus
• Alignment Length: 753
• Identity: 165/753 - (21%)
• Similarity: 297/753 - (39%)
• Gaps: 150/753 - (19%)

  Fly    14 ETLPFIEKPFAISDKERESAPENE-----TEGEDGGKDTYCGFWIFKGPSMQRFATEHMYVILYG 73
            :|:|...|.||  |...|..|.::     .||..|     .|..:|  |.:|||..
  Rat    37 KTVPRAMKKFA--DIPEEKMPHSQFSDSLEEGSFG-----LGPLVF--PCLQRFNN--------- 83

  Fly    74 LAGCVMTMTFAYFNGTIT------TLEKRYKI------PTKVSGI-ISVGNDISTMLTAAILGYY 125
             ..|.:|   |||.||:.      .:::..|:      |:|:..: :..|:|::..|.:.:..::
  Rat    84 -INCFLT---AYFLGTMAHGMIFGLVDQSLKVYVSELSPSKLETLTMGSGDDLAAFLVSLVGAHF 144

  Fly   126 AGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQ-ERDKKLCQ-- 187
            .|..:|.|||       ||.|.:|.....::.......::.: .|.|.:.|..: ::..|:|:
  Rat   145 GGRGNRVRWM-------VAACFVTGLASMVFAIPFFNYEIIK-LGTVTDELCIEGKKTTKVCERT 201

  Fly   188 --PTAGGCVQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRM 250
              |....|:          .|....|.:.|:....||.|..:::.|:.....:...|:::.....
  Rat   202 VIPHKSTCI----------AFFNFGQFLHGIAGMPFYLLAFSFIFDHVPTCSSGLYLAIADTALS 256

  Fly   251 LGPAIGYSLAAVCLRLYIEPTLEPLIGQEDPRWLG----------AWWLGWLVLAAITLVSAILL 305
            :|..:|| |..:..|::      |:  :||.:.:|          .||..:..:|.....:.:.|
  Rat   257 VGYVLGY-LVGIRNRMF------PV--KEDMKAVGHVQQFRILQRNWWRSYFAVAVFAFCTTLPL 312

  Fly   306 FMFPKQLPSARKRRLQLKQDERKQSLPLNERSLAD---------MMKTVKKLSKNKVYVYNTMAS 361
            ..||.:|..|::.||     |:.:..|..:|.|.|         ::..:..|.:|.:.:..|...
  Rat   313 SCFPSRLRGAQQIRL-----EKSKEPPTIDRRLKDKEIQPGLKGVLHAIWCLLRNPLVLTQTFCQ 372

  Fly   362 I-----LYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSAR 421
            :     |...||     |.||::::.:......|::.||...|..:..|..:.||::.:.:.|.:
  Rat   373 VTKSLTLKSSGY-----FLPKFLQSHFLIVPTNASILTGMFVLPGALIGRFLGGYIVDRLQMSTK 432

  Fly   422 AMAAWNAIVDFVTVAGILCYVAIGCEGS---------DRLNTLTTLSAGNSCSASCHCDYVHYAP 477
            .:..:..:..|::|...|......||.:         |.|..|...:|  .|:..|.|....|:.
  Rat   433 VVLKFMMVSSFISVVLFLLTFFWSCETAGFAGINDDYDGLGKLGNFTA--PCNEYCGCTMTDYST 495

  Fly   478 VCSADNITFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQF--AVDGTCPVDCFNEF 540
            :|..|...:.|||.||| ..:|.......|..|.|:.......:.:.||  ||.|||...|....
  Rat   496 ICGRDEKQYFSACFAGC-RASKPLRKEKAYYNCSCIKEGLTAPDDDGQFFDAVSGTCNTKCLTLP 559

  Fly   541 LIFLGVMCFLKLVGASSKST-NLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNY 604
            |:|  ...|...|.::..|. :.::.|:.:|....:.:||:.......||.:|..:.|....|..
  Rat   560 LLF--AFYFAATVFSNFCSVPSFMIVLKSVPASWNSMSLGVTYTIWRFLGSVPDHLLFESTSDYT 622

  Fly   605 CLVWG-KTCSNKGNCWLYDTKSMRYAL------------------NLSA------AFFIFLGGFL 644
            |..|. .:|..||.||:|:.|::.:..                  ::||      :..|..|...
  Rat   623 CNFWDINSCGEKGRCWIYNKKNLLFTFQSTSDKHIEDIKLNKGICDISARSQQGISMQISTGLLC 687

  Fly   645 NIAVWYHAKNLKIFDEEESSPKDSLKNKEVEMKTIDSN 682
            ...::.|...:|  ::.:|.|......||.|.|::.||
  Rat   688 LYGIYRHDYVVK--EKNKSLPIHVKDEKEKEKKSLISN 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	134/613 (22%)
Slco6d1	XP_017452073.1	MFS	84..585	CDD:475125	116/545 (21%)