Protein Alignment Oatp58Da and Oatp33Ea

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001260417.1
• Gene: Oatp33Ea / 34660
• FlyBaseID: FBgn0032433
• Length: 745
• Species: Drosophila melanogaster
• Alignment Length: 722
• Identity: 234/722 - (32%)
• Similarity: 370/722 - (51%)
• Gaps: 105/722 - (14%)

  Fly    49 CGFWIFKGPSMQRFATEHMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDI 113
            ||...:..|.:|::||..|::.:|||.|.:..|::.||..|:||||||:|||::.:|||..||:|
  Fly    18 CGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEI 82

  Fly   114 STMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTN 178
            |.::.:.||.|..|.|:||||:..|::.....|.:....||:||||.:.||.|:|:   .::|.|
  Fly    83 SQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEY---QDSLLN 144

  Fly   179 -------------QERDKKLC--QPTAGGCVQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAY 228
                         ..:.::||  ..|...|  :::..:||.|.:|.:|.:.|||..|:|:||..|
  Fly   145 GTTGSDHSFQNISSVKTERLCGVDKTEDDC--DDLFSYVPLVLIFLSQFVLGVGNTLYYSLGQTY 207

  Fly   229 MDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEPTLEPLIGQEDPRWLGAWWLGWLV 293
            :||||.|..||.||:::..|||:||.:|:....:.|..:|:||..|||..:||||||||||||::
  Fly   208 LDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDPTKTPLIDSKDPRWLGAWWLGWVI 272

  Fly   294 LAAITLVSAILLFMFPKQLPSARKRR------LQLKQD----ERKQSLPLNER------------ 336
            |..:..:.:.|:.:||||||.....|      |.|:|.    :|:::|.|:.|
  Fly   273 LGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGA 337

  Fly   337 ---------SLADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATM 392
                     .|.|..:.:.:|.:||:.::|.::::.|..|...:..|..||:|.|:.:.|..||:
  Fly   338 AAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATI 402

  Fly   393 ATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVAIGCEGSDRLNTLTT 457
            ..|.:::.....|::.||.|:||.|||...:..||.||..:::.|.:.|..:.|..:..:.....
  Fly   403 IVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFSMTQAGQ 467

  Fly   458 LSAGNSCSASCHCDYVHYAPVC-SADNITFISACHAGCSERTKDALGRTIYTGCECLGS------ 515
            |:..::|:.:|.|:.:.|.||| ...:.||.|||||||  |..:|..: :|..|.|:.:
  Fly   468 LNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGC--RGYNATSK-LYEDCSCVVNDPAPKS 529

  Fly   516 ------SSLNSEPESQFAV--------------------------------------DGTCPVDC 536
                  :.|...||.:...                                      .|.|..:|
  Fly   530 AAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNC 594

  Fly   537 FNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLI 601
            ...|..|......:...|:|.:..|:|:..|.:..::|:||.||..|..|||..||.||.||.||
  Fly   595 NWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLI 659

  Fly   602 DNYCLVWGKTCSNKGNCWLYDTKSMRYALNLSAAFFIFLGGFLNIAVWYHAKNLKIFDEEESSPK 666
            |:.||||.|||:..|||.|||....||:||..:....|:|...:..|||:.:||.|:.::|:..:
  Fly   660 DSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKEAKEE 724

  Fly   667 DSLKNKE 673
            :....|:
  Fly   725 ERANRKD 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	214/655 (33%)
		MFS	69..>425	CDD:119392	140/401 (35%)
		KAZAL_SLC21	462..514	CDD:238650	21/52 (40%)
Oatp33Ea	NP_001260417.1	OATP	36..684	CDD:281175	214/655 (33%)
		MFS	40..>280	CDD:119392	99/244 (41%)
		DUF4064	364..447	CDD:290013	25/82 (30%)
		KAZAL_SLC21	470..521	CDD:238650	20/53 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446196
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28658
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4773
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3798
	8	7.860