Protein Alignment Oatp58Da and Oatp30B

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_061511392.1
• Gene: Oatp30B / 3291790
• VectorBaseID: AGAMI1_001745
• Length: 1336
• Species: Anopheles gambiae
• Alignment Length: 793
• Identity: 204/793 - (25%)
• Similarity: 331/793 - (41%)
• Gaps: 194/793 - (24%)

  Fly    46 DTY---CGFWIFKGPSMQRFATEHMYVILYG-LAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGI 106
            |.|   ||....:..::|.||...::|:|.. |......::..|.|..|||:|||::||:.:||:
Mosquito   107 DDYMRDCGILNCRPSAVQHFARIKVFVLLLSILVTLQQALSSGYINSVITTIEKRFEIPSSLSGL 171

  Fly   107 ISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGED---------- 161
            |:...:|..::|...:.|....||.|.|:|||.:.:....|:....||   .||.
Mosquito   172 IASSYEIGNVITVIFVSYLGSRRHIPVWIGIGAVIMGIGSLVFMLPHF---TGEPNPGILIDNKT 233

  Fly   162 -----ALQLTRE----FGQVNETLTNQERDKKLCQPTAGG--CVQEEVGLWVPQVFLFAAQLISG 215
                 .|...||    .|:::.:|:|    ..|......|  |::.:...:.|.:....||::.|
Mosquito   234 SDNICRLVSVREQDMGLGRLSNSLSN----PPLTSHNLRGDNCLKSKASTFGPVILFVIAQILLG 294

  Fly   216 VGQALFYTLGIAYMDDNTSKAKTP----AMLSMSTFLRMLGPAIGYSLAAVCLRLYIEP------ 270
            .|.:..:|||..|:||:..|..:.    ||.||:.|    ||.:|:.|.|..|..:::.
Mosquito   295 GGGSPLFTLGTTYVDDHVRKESSSMYIGAMYSMAAF----GPVLGFLLGAYLLSFHMDSFSGSDI 355

  Fly   271 TLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKR---------RLQLKQDE 326
            .::|    :|.||:|.||.|:||...:.::.|:..|.|||.|...:|:         :||.....
Mosquito   356 NIDP----DDRRWVGMWWGGFLVCGILLIIVAVPFFSFPKVLTREKKKIRIAEQRLPQLQQLTSN 416

  Fly   327 RKQSLPLNERSLA---------------------------------------------------D 340
            ...|||.::.:||                                                   |
Mosquito   417 NSSSLPRSQPNLAQQQQQQTGTLQQQPLPSQQQQQQQQTGHGANNAAPQANKTGEDTGYGKDIKD 481

  Fly   341 MMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAG 405
            :.:::.:|..|.||:...:.:.:.......:.:|.|||:|||:....:.|::.||::|:..:..|
Mosquito   482 IPQSMWRLVTNPVYIVTCLGACMELMIVSGFVVFLPKYLETQFSLGKSQASVFTGSIAVPGACIG 546

  Fly   406 ILISGYVISKY--KPSARAMAAWNAIVDFVTVAGILCYVA------IGCEGSDRLNTLTTLSAGN 462
            |.|.|.::.::  ||        ...|.||.::.::|...      :|||......  ||:...|
Mosquito   547 IFIGGCILKRFQLKP--------KGAVQFVLISNLICLSCYGLLFFLGCENLKMAG--TTIPYYN 601

  Fly   463 S---------------CSASCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYTGCEC 512
            |               |:..|.|......|||..:.:|:.|.|||||:..:..    :.||.|.|
Mosquito   602 SSAHSVEPFQVNLTAACNFGCECHMYDVEPVCGNNGLTYFSPCHAGCTAFSSS----SNYTNCAC 662

  Fly   513 LGSSSLNSE-------PESQ---------------FAVDGTCPVDC--FNEFLIFLGVMCFLKLV 553
            :.::..|:.       .::|               .|..|.|...|  ...|||.|..|.|   |
Mosquito   663 VQANVTNNSIYRGAEGTQAQALNAHEAFAEVTVVPVATAGVCNTPCRTIYPFLILLFFMTF---V 724

  Fly   554 GASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCSNK-GN 617
            .||::...|::.||.:..:|::||||:..:...|.|:||:||.||.|||:.||:|..||..| |.
Mosquito   725 VASTQMPLLMIVLRSVSEEERSFALGMQFVIFRLFGYIPAPIVFGNLIDSSCLLWKSTCGEKGGR 789

  Fly   618 CWLYDTKSMRYA-LNLSA-----AFFIFLGGFLNIAVWYHAKNLKIFDEEESSPKDSLKNKEV-- 674
            |.:||.:..||. :.|.|     |..||      |..|:..:..|..|:......:.|....:
Mosquito   790 CLIYDIEKFRYKYVGLCASIKIIALVIF------IIDWWLVRRRKNLDKMNPLSTNELVGSIISL 848

  Fly   675 -----EMKTIDSN 682
                 |..|:|.|
Mosquito   849 DKLFEEKSTLDEN 861

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	181/698 (26%)
Oatp30B	XP_061511392.1	None