Protein Alignment Oatp58Da and Slco6c1

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_775460.1
• Gene: Slco6c1 / 287006
• RGDID: 708431
• Length: 701
• Species: Rattus norvegicus
• Alignment Length: 735
• Identity: 168/735 - (22%)
• Similarity: 282/735 - (38%)
• Gaps: 120/735 - (16%)

  Fly     2 TEERGKVDLEKSETLPFIEKPFAISDKERESAPENETEGE-------DGGKDTYCGFWIFKGPSM 59
            ||...|:| ....|:|.:.|.|    |.|.....:.|..|       ...|:...|......|.:
  Rat    21 TEGLKKID-TYLRTIPTVTKKF----KGRPQKKRSPTSAELLLDPKYSASKEGPFGLGPLVFPCL 80

  Fly    60 QRFATEHMYVI-----------LYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDI 113
            |||.....::|           |:.||..::.:..     ::.||.||.......||.|     :
  Rat    81 QRFNNIDCFMIFFIASVLIHGALFALADMILNLYH-----SLLTLSKRELYFMDFSGYI-----V 135

  Fly   114 STMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQ-----VN 173
            |: |.|..:.::.|..:|.:|       |.|.|:|.:....|.|......::.:..||     |.
  Rat   136 SS-LVAIFVAHFGGKGNRTKW-------IAAACILMAFGSILLGFPFSKYEIMKSGGQRVELCVE 192

  Fly   174 E---------TLTNQERDKKLCQPTAGGCVQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAYM 229
            |         |.:|.:|.|.:|                   |....|.::|:.....|.||..::
  Rat   193 ENKRRNIHCVTNSNPDRTKCIC-------------------FFIIGQCLNGIAGMPIYILGKTFI 238

  Fly   230 DDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEPTLEPLIGQEDPR-----WLGAWWL 289
            .|:.........|::.....::|..:|....   ::....|..|.|...:..:     ..| ||.
  Rat   239 LDHVPTRSAGFYLALGHSAHLMGYFLGIFGG---MKNLSPPPKEKLSAVDSAKIHLLLQFG-WWK 299

  Fly   290 GWLVLAAITLVSAILLFMFPKQLPSARKRRLQLKQDERKQSLPLNERSLAD---------MMKTV 345
            .:|.:|||:....::|..||..||.|.|    ||..:||:. |..::.|.|         .:..:
  Rat   300 TFLFVAAISFSVFLVLLCFPTSLPGAHK----LKLAKRKEP-PTFDKRLKDQKIQPRFKGFVFAI 359

  Fly   346 KKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISG 410
            ..:.:|.:.:...|..:...|.:.....|.|.:::||:..:..:|:|.||...:.....|..:.|
  Rat   360 WYMLRNPLLMTQAMCKVSESFAFHTSLEFLPYHLQTQFSITPQIASMLTGLFVIPGGVIGHFLGG 424

  Fly   411 YVISKYKPSARAMAAWNAIVDFVTVAGILCYVAIGCEGS---------DRLNTLTTLSAGNSCSA 466
            .::.:.:.:.:....::.:...|:||..|....:.||.:         |.|..|..|:||  |:.
  Rat   425 LIVDRLEMTNKNKLKFSLVTSVVSVALFLLIFFVECETTKFAGINEDYDGLGKLGNLTAG--CNY 487

  Fly   467 SCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQF--AVD 529
            .|.|....|:.||..|...:.|.|.|||| .||.......|..|.|:......|:.:..|  |.|
  Rat   488 HCACTTSLYSSVCGRDEKEYFSPCFAGCS-ATKVQQNEKTYYNCSCIKEGLTTSDADGHFIDATD 551

  Fly   530 GTCPVDCFNEFLIFLGVMCFLKLVGASSKSTN-LLLALRCMPPDEKTFALGLGSMAASLLGFIPS 593
            |||..:|....|.|  ...|...|.::..||. :|:.|:.:|.:..:...|:..........:|.
  Rat   552 GTCNSNCLTLPLFF--AFYFSATVFSTMCSTPIILIILQSVPANFSSLGQGVTVAITKFTASVPE 614

  Fly   594 PIFFGWLIDNYCLVWG-KTCSNKGNCWLYDTKSMRYA-LNLSAAFFIFLGGFLN---IAVWYHAK 653
            |..||......|..|. ..|..:..||:|:..::.|. :.:..:|.:|. ..||   |.::.:..
  Rat   615 PALFGTASSVACKFWDINACGVREKCWIYNKTTLVYVFIGIWVSFKLFT-ALLNIYAIHIYDYVV 678

  Fly   654 NLKIFDEEESSPKDSLKNKE 673
            ..||.|.:.:..|.|...||
  Rat   679 KGKISDSKTTHVKASKAQKE 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	137/610 (22%)
Slco6c1	NP_775460.1	MFS	86..588	CDD:475125	124/552 (22%)