Protein Alignment Oatp58Da and Slco1a4

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_109612.1
• Gene: Slco1a4 / 28250
• MGIID: 1351896
• Length: 670
• Species: Mus musculus
• Alignment Length: 661
• Identity: 180/661 - (27%)
• Similarity: 299/661 - (45%)
• Gaps: 93/661 - (14%)

  Fly    80 TMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVA 144
            :::..|.|..:|.:|:::.|||.|.|:|:...:|..:|....:.|:....|||..:|:|...:..
Mouse    34 SLSGTYMNSMLTQIERQFGIPTSVVGLINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGL 98

  Fly   145 FCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQERDKKLCQPTAG--GCVQEEVGL-WVPQVF 206
            .|.|.|..|||.|..|....:.......:.:....|...:..:||..  .||:|...| |   ::
Mouse    99 GCFLISIPHFLMGRYEYETTILPTSNLSSNSFVCTENRTQTLKPTQDPTECVKEMKSLMW---IY 160

  Fly   207 LFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEP- 270
            :....:|.|:|:.....|||:|::|......:|..:.:......:||.||..|.:.|..:|::.
Mouse   161 VLVGNIIRGMGETPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLGSSCANIYVDTG 225

  Fly   271 ---TLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKRRLQ--------LKQ 324
               |.:..|...|.||:||||:|:||.|.:.::::|..|.|||.|   .|..||        .|:
Mouse   226 SVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTL---LKEGLQDNGDGTENAKE 287

  Fly   325 DERKQSLPLNERSLA-DMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAA 388
            ::.::.:....|.:. |....:|.||.|.:|:...:.|::....::..:.|.|||:|.||.:|.|
Mouse   288 EKHREKIKEENRGITKDFFLFMKSLSCNPIYMIFILISVIQVNAFINSFTFMPKYLEQQYGKSTA 352

  Fly   389 MATMATGTVALGFSAAGILISGYVISKYKPSARAMA---AWNAIVDFVTVAGILCYVA--IGCEG 448
            ......|...|.....|.||.|.::.|:|.:.:..|   .|.::.::     :|.:|:  :.|:.
Mouse   353 EIVFLMGLYMLPPICLGYLIGGLIMKKFKITVKKAAYIGFWLSLTEY-----LLSFVSYIMTCDN 412

  Fly   449 SDRLNTLTTLSAG------------NSCSASCHCDYVHYAPVCSADNITFISACHAGCSERTKDA 501
            .. :..|||...|            ..|:..|.|....:.|||..:.::::|||.||| |::...
Mouse   413 FP-VAGLTTSYEGVQHPLYVENNVLADCNTKCSCLTNTWDPVCGDNGLSYMSACLAGC-EKSVGT 475

  Fly   502 LGRTIYTGCECLGSSSLNSEPESQFAVDGTCP--VDCFNE---FLIFLGVMCFLKLVGASSKSTN 561
            ....::..|.|:.||...|      ||.|.|.  .:|.|:   |||...:.||:..:||   ...
Mouse   476 GTNMVFQNCSCIQSSGNAS------AVLGLCDKGPECANKLQYFLIISIIGCFIFSLGA---IPG 531

  Fly   562 LLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGK-TCSNKGNCWLYDTKS 625
            .::.||||..:||:..:||.:....:||.||:||:||.|||..||.||. .|...|.|.:||..|
Mouse   532 YMVLLRCMKSEEKSLGVGLHTFCMRILGGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINS 596

  Fly   626 -----------MRYALNLSAAFFIFLGGFLNIAVWYHAKNLKIF------DEEESSPKD-SLKNK 672
                       :|.|..|.|.|.:.|              ::.|      |..::.|.: .|..|
Mouse   597 FRRIYLGLPAALRGASFLPALFILIL--------------MRKFQFPGDIDSSDTDPAEMKLTAK 647

  Fly   673 EVEMKTIDSNP 683
            |.:...:..:|
Mouse   648 ESKCTNVHRSP 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	167/595 (28%)
Slco1a4	NP_109612.1	oat	1..625	CDD:273279	173/626 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	649..670		1/10 (10%)