Protein Alignment Oatp58Da and SLCO3A1

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_037404.2
• Gene: SLCO3A1 / 28232
• HGNCID: 10952
• Length: 710
• Species: Homo sapiens
• Alignment Length: 662
• Identity: 183/662 - (27%)
• Similarity: 291/662 - (43%)
• Gaps: 121/662 - (18%)

  Fly    84 AYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLL 148
            ||....:||||:|:.:.:...|:|:...:|..:.....:.|:....||||.:|.|.:.:....||
Human    58 AYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALL 122

  Fly   149 TSSLHFL-----YGAGE--------DALQLTREFGQV---------NETLTNQERDKKLCQPTAG 191
            ::...||     |.|||        |........|..         |.|.||
Human   123 SALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICRNRTATN------------- 174

  Fly   192 GCVQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIG 256
                      :..:.|..||::.|:|......||::|:||:..:..:...:.:...:.:.|||.|
Human   175 ----------MMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACG 229

  Fly   257 YSLAAVCLRLYIE----PTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQL----- 312
            :.|.:.|.::|::    .|....|..:||||:||||.|:|:..|:...|::|:|.||:.|
Human   230 FILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSE 294

  Fly   313 PSARKRRLQLKQDERKQSLPLNE---------------RSLADMMKTVKKLSKNKVYVYNTMASI 362
            |:....:..|.:.|.::..|.|.               :.|..:.|..|.|..|.|:....:|:.
Human   295 PAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAAC 359

  Fly   363 LYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWN 427
            :.......:..|..||:|.|:..:.:.|....|..|:..:..||.:.|.::.|...||.......
Human   360 MEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMA 424

  Fly   428 AIVDFVTVAGILCYVA---IGCEGSDRLNTLTTLSAGNS------------CSASCHCDYVHYAP 477
            .:|:.|:.|   |||:   :||:......  .|:..|||            |:.:|.|....:.|
Human   425 MLVNLVSTA---CYVSFLFLGCDTGPVAG--VTVPYGNSTAPGSALDPYSPCNNNCECQTDSFTP 484

  Fly   478 VCSADNITFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEP-ESQFAVDGTCP-VDCFNEF 540
            ||.||.||::|||.|||:.        |..|||.|     |.:.| |:...|.|.|| ..|...|
Human   485 VCGADGITYLSACFAGCNS--------TNLTGCAC-----LTTVPAENATVVPGKCPSPGCQEAF 536

  Fly   541 LIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYC 605
            |.||.|||...|:||.:::.::::.:|.:.|:.|::|||:..:...||||||.|:.||..||:.|
Human   537 LTFLCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTC 601

  Fly   606 LVWGKTCSNKGNCWLYDTKSMRY---ALNLSAAFFIFLGGFLNIAVWY-HAKNLKIFDEEESSPK 666
            |.|...|..:|.|.|||....||   ::.::...|.|:   |....|. ..||.|.:
Human   602 LFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFI---LYTTTWQCLRKNYKRY-------- 655

  Fly   667 DSLKNKEVEMKT 678
              :||.|..:.|
Human   656 --IKNHEGGLST 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	170/604 (28%)
SLCO3A1	NP_037404.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		MFS_SLCO3_OATP3	39..563	CDD:340960	144/545 (26%)