Protein Alignment Oatp58Da and Slco5a1

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_766429.2
• Gene: Slco5a1 / 240726
• MGIID: 2443431
• Length: 850
• Species: Mus musculus
• Alignment Length: 661
• Identity: 183/661 - (27%)
• Similarity: 298/661 - (45%)
• Gaps: 95/661 - (14%)

  Fly    67 MYVIL-----YGLAGCVMT-----MTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAI 121
            :||:|     :.:..|.:|     |...|.:..|||:|:||.:.:..||::....||..::....
Mouse   123 LYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVF 187

  Fly   122 LGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFL---YGAGEDALQLTREFGQVNETLTNQERDK 183
            :.|:.|...||.|:.:|.|.|.....|.:..||:   |              |:.|...:...|
Mouse   188 VSYFGGRGRRPLWLAVGGLLIAIGAALFALPHFISPPY--------------QIQELNASASND- 237

  Fly   184 KLCQ---PTA----GGCVQEEVG--LWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTP 239
            .|||   .||    ..|.::..|  .|:.......||::.|:|....||||..|:|||..|....
Mouse   238 GLCQNGNSTAILEPPPCPKDSGGNSHWIYVALFVCAQVLIGMGSTPIYTLGPTYLDDNVKKDNAS 302

  Fly   240 AMLSMSTFLRMLGPAIGYSLAAVCLRLYIEPTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAIL 304
            ..|::...:..||||:||.|..:.:..|::|.....:.|.|||::|.||.|:|:.|....:....
Mouse   303 LYLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQSDPRFIGNWWSGFLLCAIAMFLVIFP 367

  Fly   305 LFMFPKQLPSARKRRLQLKQD----------ERKQSLPLNER-SLADMMKTVKKLSKNKVYVYNT 358
            :|.|||:||...|::.:...|          :...|..:|:: |.....|.|:.|.:..|.:.:.
Mouse   368 MFTFPKKLPPRHKKKKKFSADVVIDDDIIKEKSNTSEQMNKKVSPMGFGKNVRDLPRAAVRILSN 432

  Fly   359 MASILYFFGY-------MVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKY 416
            |..:.....|       ..:..|.||:||:|:...|:.|::.||.:.:..:..||::.||:|.|.
Mouse   433 MTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKL 497

  Fly   417 KPSARAMAAWNAIVDFVTVAGILCYVAIGCEGSDRLN--------------TLTTLSAGNSCSAS 467
            |..||..|....|...|:   :||:..:...|.:.:|              |:...:...||:.:
Mouse   498 KLGARESAKLAMICSGVS---LLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVN 559

  Fly   468 CHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEP---------- 522
            |.|....|.|||.:|.||:.:.|.|||........|...||.|.|:.|..:.:.|
Mouse   560 CGCKIHEYEPVCGSDGITYFNPCLAGCINSGNLTTGVRNYTECTCVQSRQVITPPTVGQRSQLRV 624

  Fly   523 --------ESQFAVDGTCPVDC--FNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFA 577
                    |:.:||.|.|...|  ...||:||.::.|   :.|.::.:.:::.||.:..:|:.||
Mouse   625 VIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF---ITACAQPSAIIVTLRSVEDEERPFA 686

  Fly   578 LGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCSNKGNCWLYDTKSMRYALNLSAAFFIFLGG 642
            ||:..:....|.:||:||:||.:||..|::|.:.|..:|:||.|:..|.|:.....||...|:|.
Mouse   687 LGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGF 751

  Fly   643 FLNIAVWYHAK 653
            ......||..|
Mouse   752 IFIFLAWYSIK 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	174/632 (28%)
		MFS	69..>425	CDD:119392	108/395 (27%)
		KAZAL_SLC21	462..514	CDD:238650	20/51 (39%)
Slco5a1	NP_766429.2	MFS_SLCO5_OATP5	131..676	CDD:340962	148/565 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810