Protein Alignment Oatp58Da and Slco2a1

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_201571.2
• Gene: Slco2a1 / 24059
• MGIID: 1346021
• Length: 643
• Species: Mus musculus
• Alignment Length: 636
• Identity: 177/636 - (27%)
• Similarity: 298/636 - (46%)
• Gaps: 66/636 - (10%)

  Fly    67 MYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHR 131
            ::|:.:||......:..|||..::||:|||:.:.:..||:||..|:||..:....:.|:....:|
Mouse    33 VFVLCHGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSYFGSRVNR 97

  Fly   132 PRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQER-DKKLCQPTAGGCVQ 195
            ||.:|||.|.:.|...:.:..||          |:..:...:.|..|... ...|||....|.:.
Mouse    98 PRMIGIGGLLLAAGAFVLTLPHF----------LSEPYQYASTTAGNSSHFQTDLCQKHLPGLLP 152

  Fly   196 EEVGLWVPQV---------FLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRML 251
            .:....||..         .:..|||::|||.......||:|:||......:|..:|:...:.:.
Mouse   153 SKCHSTVPDTQKETSSMWSLMVVAQLLAGVGTVPIQPFGISYVDDFAEPTNSPLYISILFAIAVF 217

  Fly   252 GPAIGYSLAAVCLRLYIE----PTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQL 312
            |||.||.|.:|.||::::    .|....:...||||:||||||.|:.:...:|:::..|.||:.:
Mouse   218 GPAFGYLLGSVMLRIFVDYGRVDTATVNLSPGDPRWIGAWWLGLLISSGFLIVTSLPFFFFPRAM 282

  Fly   313 PSARKRRL----QLKQDERKQSLPLNERSLADMMKTVK----KLSKNKVYVYNTMASILYFFGYM 369
            ....:|.:    .:|.:|.|     :..||.|.:|...    :|..|.:::...::...:.....
Mouse   283 SRGAERSVIAEETMKMEEDK-----SRGSLMDFIKRFPRIFLRLLMNPLFMLVVLSQCTFSSVIA 342

  Fly   370 VYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVT 434
            ....|..|::|.||..|||.|.:..|.|.|..:|.|:|..|.::.::....:.:....|.:  :|
Mouse   343 GLSTFLNKFLEKQYDASAAYANLLIGAVNLPAAALGMLFGGILMKRFVFPLQTIPRVAATI--MT 405

  Fly   435 VAGILC--YVAIGCEGSDRLNTLTTLSAGNS-------CSASCHCDYVHYAPVCSADNITFISAC 490
            ::.|||  ...:|| .:..:..:...|..:|       |...|.|....:.|||..:.:.::|.|
Mouse   406 ISIILCAPLFFMGC-STPAVAEVYPPSTPSSIHPQPPACRRDCLCPDSVFHPVCGDNGVEYLSPC 469

  Fly   491 HAGCSER--TKDALGRTIYTGCECL--GSSSLNSEPESQFAVDGTCPVDCFNEFLIFLGVMCFLK 551
            |||||..  :..|..:.||..|.|:  ||:|         |..|:||..|....|..:.::.|:.
Mouse   470 HAGCSSLNVSSAASKQPIYLNCSCVTGGSAS---------AKTGSCPTSCAQLLLPSIFLISFVA 525

  Fly   552 LVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCS-NK 615
            |:...|.:...::.||.:..|||:||:|:..:...||.::|||..:|.|||:.|:.|...|| .:
Mouse   526 LIACVSHNPLYMMVLRVVNQDEKSFAIGVQFLLMRLLAWLPSPSLYGLLIDSSCIRWNYLCSGRR 590

  Fly   616 GNCWLYDTKSMRYA-LNLSAAFFIFLGGFLNIAV-WYHAKNLKIFDEEESS 664
            |.|..||..::|.. |.|...:.: ||..|...: |...||.:...:|.:|
Mouse   591 GACAYYDNDALRNRYLGLQVIYKV-LGTLLLFFISWRVKKNREYSLQENAS 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	166/594 (28%)
Slco2a1	NP_201571.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		MFS_SLCO2A_OATP2A	30..541	CDD:341019	141/534 (26%)