Protein Alignment Oatp58Da and Y70G10A.3

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_499267.1
• Gene: Y70G10A.3 / 190573
• WormBaseID: WBGene00013499
• Length: 690
• Species: Caenorhabditis elegans
• Alignment Length: 645
• Identity: 181/645 - (28%)
• Similarity: 297/645 - (46%)
• Gaps: 71/645 - (11%)

  Fly    29 ERESAPEN---ETEGEDGGKDTYCGFWIFKGPSMQRFATEHMYVILYGLAGCVMTMTF---AYFN 87
            |.|...||   :.|.||..:...||:.......:|.|......:::.|:  |....:|   |.|.
 Worm     8 EFEEPDENLKHKIEDEDDAEKLLCGYGACTPSWLQGFHNAKCLLVVLGI--CAFIQSFVVNAIFP 70

  Fly    88 GTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSL 152
            ..::|||:|:|:.:..:||||...|.:.:|....:.::..:.|:.||:|.|.:.:....|:.:..
 Worm    71 VGLSTLERRFKMTSTHTGIISSWYDFAVLLVVFPVCHWGNNGHKGRWIGWGGVIMALGSLICALP 135

  Fly   153 HF---LYGAGEDALQLTREFGQVNETLTNQERDKKLCQPTAGGCVQEEVGLWV-PQVFLF-AAQL 212
            |:   :|....:.|....:|||.      ..||...|   ||    :....|. |..::| ..|.
 Worm   136 HWMVDIYHPDVNDLTNQTDFGQC------ANRDDPEC---AG----KPHSSWFNPYFWMFILGQT 187

  Fly   213 ISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEPTLEPLIG 277
            :.|||....:::|..|||:|.|:..:|..|::...|...||.||.......|.||.:......|.
 Worm   188 LHGVGSTPLFSIGTTYMDENVSQKASPVYLAIHAVLTSFGPVIGVFAGGFLLNLYDDFDRVERIP 252

  Fly   278 QE--DPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKRRLQLKQDERKQSLPLNERSLAD 340
            .|  ||||:||||:|:::.:...|:.|..:..|.::||.|::.|.:........:..:|.::..|
 Worm   253 MERSDPRWVGAWWVGFIISSISALMIAFPILAFARELPEAKRHRAKDVNQCHVANGDVNAKAPRD 317

  Fly   341 MMK---TVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFS 402
            :||   .|.|:..|..::......|........:..|.||.:||....:..:|:..:..|... :
 Worm   318 LMKLPACVWKILSNPTFLVCIFVGIFESIIINGFAAFMPKILETLLSTNPTLASYLSSVVIFA-A 381

  Fly   403 AAGILISGYVISKYKPSARAMAAWNAIVD-----FVTVAGIL--C----YVAIGCEGSD-RLNTL 455
            |.|:::.|.:|.:.|.....|.....:..     |.|  |:|  |    :|.|.....| .:..:
 Worm   382 ATGVMVGGTIIRQLKLQVGGMLKMIIVCHVFALLFTT--GLLSHCPQREFVGINLGYEDLSIEKM 444

  Fly   456 TTLSAGNSCSASCHCDYVHYAPVCSADNIT---FISACHAGCSERTK-DALGRTIYTGCECLGSS 516
            ...|..::|:|.|||. :.:.|||  |..|   :.|||||||:.||. |  |.:.::||.||.|:
 Worm   445 HDFSISSTCNADCHCK-MEWNPVC--DRNTGHMYYSACHAGCTGRTTID--GSSQWSGCGCLTSN 504

  Fly   517 S--------LNSEPESQFAVDGTCPVDC-FNEFLIFLGVMCFLKLVG--ASSKSTNLLLALRCMP 570
            |        :...|:  ....|.|..|| :.|:::.  |..|:.:|.  ||...|..:: ||.:|
 Worm   505 STFHNLIHGIKEHPD--VLNQGYCHQDCGYREYILM--VTLFITVVASFASGIPTQQIM-LRVVP 564

  Fly   571 PDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCSNKGNCWLYDTKSMRYAL 630
            .|::|.|||:......||||||..|.||.:||..||.||::|....:|.:||...:.:.:
 Worm   565 FDQRTLALGVNWTFVRLLGFIPGGILFGIIIDTACLEWGESCGKATSCLVYDPFKLSWTI 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	170/598 (28%)
Y70G10A.3	NP_499267.1	MFS_SLCO4_OATP4	47..561	CDD:340961	143/541 (26%)