Protein Alignment Oatp58Da and F21G4.1

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_509659.3
• Gene: F21G4.1 / 181203
• WormBaseID: WBGene00009023
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 654
• Identity: 187/654 - (28%)
• Similarity: 307/654 - (46%)
• Gaps: 77/654 - (11%)

  Fly    66 HMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRH 130
            :::|:|..|...|......|..|.:||||||:...::.||.:....||...:...::||...|.|
 Worm    17 NIFVLLMVLVIAVQGTYLGYVVGMLTTLEKRFGFSSEKSGWLLSLYDIGHTMAILLIGYIGSHYH 81

  Fly   131 RPRWMGIG-LLTIVAFCLLTSSLHFLYGAG----EDALQLTREFGQVNETLTNQERDKKLCQPTA 190
            .||..||| :|:.::..:|...:.| ||..    |..:|....:.......||..|:   .....
 Worm    82 LPRITGIGVILSSLSMFMLALPVLF-YGTADYTQEQLMQKKEAYSVEMSCDTNGRRE---ISSQG 142

  Fly   191 GGCVQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNT-SKAKTPAMLSMSTFLRMLGPA 254
            ..|.:|........:.|...||.:|:..|.|.|:...|:|.|. .|.::|.:|.:.|.:...|||
 Worm   143 EDCWREHHEHTNAFIILAFGQLFAGIFAAPFNTIAYVYIDSNVKQKRESPFLLGLLTSMYAFGPA 207

  Fly   255 IGYSLAAVCLRLYIEPTLEP-LIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPK--QLPSA- 315
            :|:.|:::...:|......| .||..|..|:||||||:||..:..|:.|:..|.||:  :.|.:
 Worm   208 LGFMLSSILNGVYTSLGDAPDHIGTHDEHWIGAWWLGFLVCGSAYLILAVPFFFFPRTYKHPDSF 272

  Fly   316 ----RKRRLQLKQDER---KQSLPLNERSLADMMKTVKKLSKNKVYVYNTMASILYFFGYMV--Y 371
                ...|.|:..::|   |:::.|   .|.:....:|||..||||:  ||.....|..|::  |
 Worm   273 HLMLEHSRPQVSPEDRLTFKENITL---FLREFPMVLKKLITNKVYI--TMVIAWMFGSYLIGGY 332

  Fly   372 WIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARA-----MAAWNAIVD 431
            ..:.||:|||||.:||:||.:.:|.:::|..|....:.|:::|:|..:.|:     :.:|
 Worm   333 QTYLPKFIETQYGRSASMADIYSGIISVGAIAVSTALGGWILSRYNIAPRSSIICLIGSW----- 392

  Fly   432 FVTVAGILCYVAIGCEGSDRLNTLTTLSAGN------------SCSASCHCDYVHYAPVCSADNI 484
            .|.:...:..:.:|| ...::..||.:...:            .|...|:|:.|......|.:..
 Worm   393 IVILVSYIIGMNLGC-SQPKVEGLTYVDYASRWHFYHHREREQECLEYCNCETVLKFDGVSYNGQ 456

  Fly   485 TFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQFAVDGTCPVDCFNEFLIFLGVMCF 549
            .|.|.|||||:|  .|....| ::.|:|...:.::.         |....|| ..|..:|.||..
 Worm   457 NFYSPCHAGCTE--YDIYSNT-WSNCQCAYGNMVDK---------GLVHPDC-GIFFAYLAVMLI 508

  Fly   550 LKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCSN 614
            ...:|.......:::.||.:..:||..||.|.|...:|.||||:|:.:|:.||..|::|.:.|.|
 Worm   509 GLFIGNLFFMVTMMIVLRSVFDEEKVIALSLASFITNLFGFIPAPVIYGFFIDLCCILWNRQCPN 573

  Fly   615 -KGNCWLYD----TKSMRYALNLSAAFF-IFLGGFLNIAVWYHAKNLKIFDEEESSPKDSLKNKE 673
             :|||.|||    || |.:.:|   :|| :|...|..|..|. :|.:|:  .||....|..:::|
 Worm   574 ERGNCVLYDNDMFTK-MFHGVN---SFFQVFAIIFAGICYWL-SKTVKL--PEEMPMVDFPESRE 631

  Fly   674 VEMK 677
            .|.:
 Worm   632 REYR 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	172/599 (29%)
F21G4.1	NP_509659.3	OATP	18..586	CDD:460821	170/595 (29%)