Protein Alignment Oatp58Da and F53B1.8

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001294793.1
• Gene: F53B1.8 / 180528
• WormBaseID: WBGene00018739
• Length: 801
• Species: Caenorhabditis elegans
• Alignment Length: 794
• Identity: 186/794 - (23%)
• Similarity: 326/794 - (41%)
• Gaps: 163/794 - (20%)

  Fly    11 EKSETLP--FIEKPFAISDKERESAPEN----ETEGEDGGKDTYCGFWIFKGPSMQRFATEHMYV 69
            :.|:.:|  .:||  |:..||.:..|:.    |.|.....:::.||...::...:|....:...:
 Worm    44 QASQGVPPRHMEK--ALRRKEFQLPPQQHELIEREMTVLTEESQCGIGKWRPKWLQCLGKQLPMI 106

  Fly    70 ILYGLAGCV-MTMTFAYFNG----TITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHR 129
            :|.    || .::.....||    .|:::|:|:|..|...|.|....|...:|....:.|:.|..
 Worm   107 VLL----CVYCSIQGLIVNGLVPSAISSIERRFKFSTSHMGRIVQFYDFGYVLLCIPVSYFGGRH 167

  Fly   130 HRPRWMGIGLLTIVAFCLLTSSLHFL---YGAGEDALQLTREFG--QVNETLTNQERDKKLCQPT 189
            .:|..:..||..:....|:.|:.|.:   |.|.    |....||  .:...|.|.     :..|.
 Worm   168 SKPAVLAAGLACMALGSLIFSAPHIMSDSYSAS----QSNMSFGTCSIEHLLQND-----MTSPE 223

  Fly   190 AGGCVQ---------EEVGLWVPQVFLFA-AQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSM 244
            |...:|         ....|:   .:||. |..:.|:|....:|:|::|:|:|...||:...:.:
 Worm   224 ALAQIQCQSENQDQHSSSNLY---FYLFCFAHFLHGIGATPLFTIGVSYIDENVGTAKSSLFVGI 285

  Fly   245 STFLRMLGPAIGYSLAAVCLRLYI-------EPTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSA 302
            .....:.|||||:..|:|.|:.:.       |..|:...|:.||.|:|||||.::..:.:..|:.
 Worm   286 FYSFAVFGPAIGFLGASVSLQYHTDFWHLPPEQILKVSSGETDPTWVGAWWLSFIAASFVGFVAV 350

  Fly   303 ILLFMFPKQLPSARKRRLQLKQDERKQSLPLNERSLADMMKTVK---KLSKNKVYVYNT------ 358
            :.|...||.||::      ||....:    |::.::|:..:|.:   ....||....|:
 Worm   351 LPLASLPKVLPAS------LKWHRSR----LHDAAVANRRRTPECCGMPGSNKTAALNSDAPMAE 405

  Fly   359 MASILY-------------------------FFGYMVYWI--------------------FTPKY 378
            .||:||                         .:..:..|:                    |..||
 Worm   406 QASLLYSSIPARGRGPLWYKIWLDVRHIPIAIYRILTNWLFMIITSAMAIDSLVVTGASSFMSKY 470

  Fly   379 IETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVA 443
            :|.|:....:.|.:..|.|.:..:..|.:::|.:::.::.::..|..:...:.|:::.....|:
 Worm   471 LERQFSVRPSKANLLIGCVMVPMAGMGCMVTGGIVNHFRLNSSKMLKFAIGLIFLSLLFSPMYL- 534

  Fly   444 IGCE-----GSDRL-----NTLTTLSAG--------NSCSASCHCDYVHYAPVCS----ADNITF 486
            |.|.     |.|..     .::...:|.        |||:..|.||...|.|||:    ....|:
 Worm   535 IYCPHAPLVGVDSAYPEFDGSIPDYNATYSKDPELMNSCNKQCTCDPSEYRPVCAELDDGRQFTY 599

  Fly   487 ISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQFAVDGTCPVDCFNEFLIFLGVMCFLK 551
            .|.|:|||||....:|..  ||.|.|:.:   |::...:....|.|...| .|.|.||.:...|.
 Worm   600 YSPCYAGCSETYSASLKE--YTECSCVPT---NTKNRPRIVKKGVCEPQC-TELLWFLLLFAPLS 658

  Fly   552 LVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVW-GKTC-SN 614
            ....:.....:.:.||.:..:|::||||:..:...::|.||:|:.|||:.|..|:.: ..:| |:
 Worm   659 FCTFAIAVPIISVILRTVDYNERSFALGIQWIMIRVIGTIPAPVLFGWMFDVSCIKYQSDSCGSS 723

  Fly   615 KGNCWLYDTKSMRYALNLSAAFFIFLGGFLNIAVWYHAKNLKIF------DEEESSPKDSLKNKE 673
            .|.|.:|   |.:|..||...|.| .|..:.:|:....  |.||      |.....|....:.:|
 Worm   724 SGGCLMY---SNQYLANLFLTFTI-SGQIITLAILIVV--LMIFGAALNDDANHGPPTGDHQLEE 782

  Fly   674 ---VEMKTIDSNPE 684
               ||.|.::  ||
 Worm   783 ASLVERKELE--PE 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	154/663 (23%)
		MFS	69..>425	CDD:119392	94/436 (22%)
		KAZAL_SLC21	462..514	CDD:238650	23/55 (42%)
F53B1.8	NP_001294793.1	oat	72..763	CDD:273279	170/729 (23%)
		MFS	105..>360	CDD:119392	68/270 (25%)
		KAZAL_SLC21	569..625	CDD:238650	23/57 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810