Protein Alignment Oatp58Da and Slco3a1

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_803434.1
• Gene: Slco3a1 / 140915
• RGDID: 620227
• Length: 710
• Species: Rattus norvegicus
• Alignment Length: 651
• Identity: 184/651 - (28%)
• Similarity: 298/651 - (45%)
• Gaps: 99/651 - (15%)

  Fly    84 AYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLL 148
            ||....:||||:|:.:.:...|:|:...:|..:.....:.|:....||||.:|.|.:.:....||
  Rat    58 AYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALL 122

  Fly   149 TSSLHFL-----YGAGEDALQLT-REFGQVNETLTNQERDKKL-CQ-PTAGGCVQEEVGLWVPQV 205
            ::...||     |.|||...... |:....|.:.:::..|..| |: .||...:         .:
  Rat   123 SALPEFLTHQYKYEAGEIRWGAEGRDVCATNGSSSDEGPDPDLICRNRTATNMM---------YL 178

  Fly   206 FLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIE- 269
            .|..||::.|:|......||::|:||:..:..:...:.:...:.:.|||.|:.|.:.|.::|::
  Rat   179 LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDA 243

  Fly   270 ---PTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQL-----PSARKRRLQLKQDE 326
               .|....|..:||||:||||.|:|:..|:...|::|:|.||:.|     |.....:..|.:.|
  Rat   244 VFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPGMESEQAMLPERE 308

  Fly   327 RKQSLPLNE---------------RSLADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTP 376
            .::..|.|.               :.|..:.|..|.|..|.|:....:|:.:.......:..|..
  Rat   309 YERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIVLAACMEIAVVAGFAAFLG 373

  Fly   377 KYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCY 441
            ||:|.|:..:.:.|....|..|:..:..||.:.|.::.|...||........:|:.|:.|   ||
  Rat   374 KYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTA---CY 435

  Fly   442 VA---IGCEGSDRLNTL----TTLSAGNS------------CSASCHCDYVHYAPVCSADNITFI 487
            |:   :||:      |:    .|:..||:            |:.:|.|....:.|||.||.||::
  Rat   436 VSFLFLGCD------TVPVAGVTVRYGNNSARGSPLDPYSPCNNNCECQTDSFTPVCGADGITYL 494

  Fly   488 SACHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQFAVDGTCP-VDCFNEFLIFLGVMCFLK 551
            |||.|||:.        |..|||.||    ....||:...|.|.|| ..|...||.||.|||...
  Rat   495 SACFAGCNS--------TNLTGCACL----TTVPPENATVVPGKCPSPGCQEAFLTFLCVMCVCS 547

  Fly   552 LVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCSNKG 616
            |:||.:::.::::.:|.:.|:.|::|||:..:...||||||.|:.||..||:.||.|...|..:|
  Rat   548 LIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQG 612

  Fly   617 NCWLYDTKSMRY---ALNLSAAFFIFLGGFLNIAVWY-HAKNLKIFDEEESSPKDSLKNKEVEMK 677
            .|.|||....||   ::.::...|.|:   |....|. ..||.|.:          :||.|..:.
  Rat   613 ACVLYDNVVYRYLYVSIAIALKSFAFI---LYTTTWQCLRKNYKRY----------IKNHEGGLS 664

  Fly   678 T 678
            |
  Rat   665 T 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	171/593 (29%)
		MFS	69..>425	CDD:119392	94/372 (25%)
		KAZAL_SLC21	462..514	CDD:238650	22/63 (35%)
Slco3a1	NP_803434.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		OATP	41..619	CDD:281175	170/590 (29%)
		MFS	47..>286	CDD:119392	65/236 (28%)
		KAZAL_SLC21	467..511	CDD:238650	20/51 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339154
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750