Protein Alignment Oatp58Da and Slco1a5

DIOPT Version :10

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_570931.1
• Gene: Slco1a5 / 108096
• MGIID: 1351865
• Length: 670
• Species: Mus musculus
• Alignment Length: 639
• Identity: 173/639 - (27%)
• Similarity: 300/639 - (46%)
• Gaps: 73/639 - (11%)

  Fly    56 GPSMQRFATE--------HMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGND 112
            |.:.:|.||.        .|:::....|....:::..|.|..:|.:|:::.|||.:.|:|:...:
Mouse     2 GETEKRIATHGVRCFSKIKMFLLALTCAYVSKSLSGIYMNSMLTQIERQFDIPTSIVGLINGSFE 66

  Fly   113 ISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLT 177
            |..:|...::.|:....|||..:|||.:.:...|.|.|..|||.|..|....::......:.:..
Mouse    67 IGNLLLIILVSYFGTKLHRPIMIGIGCVIMGLGCFLMSLPHFLMGRYEYETTISPTSNLSSNSFL 131

  Fly   178 NQERDKKLCQPT--AGGCVQEEVGL-WVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTP 239
            ..|...:..:||  ...||:|...| |   :::....:|.|:|:.....|||:|::|......:|
Mouse   132 CMENRTQTLKPTQDPAECVKEMKSLMW---IYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSP 193

  Fly   240 AMLSMSTFLRMLGPAIGYSLAAVCLRLYIEP----TLEPLIGQEDPRWLGAWWLGWLVLAAITLV 300
            ..:.:....:|:||.:|..|.:.|.|:|::.    |.:..|...|.||:||||:|:||.|.:.::
Mouse   194 LYIGILESGKMIGPIVGLLLGSFCARIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNIL 258

  Fly   301 SAILLFMFPKQLPSARKRRLQ--------LKQDERKQSLPLNERSLA-DMMKTVKKLSKNKVYVY 356
            ::|..|.|||.||   |..||        .|:::.::......|.:. |.:..:|.||.|.:|:.
Mouse   259 TSIPFFFFPKTLP---KEGLQDNVDRTENDKEEKHREKAKEENRGITKDFLPFMKSLSCNPIYML 320

  Fly   357 NTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYK---P 418
            ..:.|:|....::..:.|.|||:|.||.:|.:...:..|...|.....|.|:.|:::.|::   .
Mouse   321 LILTSVLQINAFINMFTFLPKYLEQQYGKSTSEVVLLIGVCNLPPICIGYLLIGFIMKKFRITVK 385

  Fly   419 SARAMAAWNAIVDFVTVAGILCY--VAIGCEGSDRLNTLTTLSAG------------NSCSASCH 469
            .|..||...::.::     :|.|  ..|.|: :.::..|||...|            ..|:..|.
Mouse   386 KAAYMAFCLSLFEY-----LLSYFHFMISCD-NFQVAGLTTSYEGVQHPLYVENKVLADCNTRCS 444

  Fly   470 CDYVHYAPVCSADNITFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEPESQFAVDGTCP- 533
            |....:.|||..:.::::|||.||| |::.......::..|.|:.||..:|      ||.|.|.
Mouse   445 CLTNTWDPVCGDNGLSYMSACLAGC-EKSVGMGTHMVFQNCSCIQSSGNSS------AVLGLCKK 502

  Fly   534 -VDCFNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFF 597
             .:|.|:...||.:......:.:.:.....::.|||:..:||:..:||.:....:...||:||:|
Mouse   503 GPECANKLQYFLIMSVIGSFIYSITAIPGYMVLLRCIKSEEKSLGIGLHAFCTRIFAGIPAPIYF 567

  Fly   598 GWLIDNYCLVWGK-TCSNKGNCWLYDTKSMR-------YALNLSA---AFFIFL 640
            |.|||..||.||. .|...|.|.:|:..:.|       .||..|:   ||||.:
Mouse   568 GALIDRTCLHWGTLKCGEPGACRMYNINNFRRIYLVLPAALRGSSYLPAFFILI 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:460821	161/594 (27%)
Slco1a5	NP_570931.1	oat	1..625	CDD:273279	173/639 (27%)