Protein Alignment Oatp58Da and Slco2b1

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_011239939.1
• Gene: Slco2b1 / 101488
• MGIID: 1351872
• Length: 697
• Species: Mus musculus
• Alignment Length: 683
• Identity: 162/683 - (23%)
• Similarity: 300/683 - (43%)
• Gaps: 119/683 - (17%)

  Fly    68 YVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRP 132
            :|:.:.|......|...|...:|:|:|||:.:.:::||:::..|::..:.....:.|:....|||
Mouse    57 FVLCHSLLQLTQLMISGYLKSSISTVEKRFGLSSQISGLLAAFNEVGNVSLILFVSYFGSRVHRP 121

  Fly   133 RWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFGQVNETLTNQERD--KKLCQPTA----- 190
            |.:|.|.|.:....||.:..||          ::..:...:.:..|:..|  ..||.||.
Mouse   122 RMIGYGALLVATAGLLMALPHF----------ISEPYRYDHSSSDNRSLDFEASLCLPTTMAPAS 176

  Fly   191 ----GGCVQEE-------VGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSM 244
                |.|....       ||:      :||||.:.|:|.......||:|:||....:.:|..:.:
Mouse   177 ALSNGSCSSHTETKHLTMVGI------MFAAQTLLGIGGVPIQPFGISYIDDFAHHSNSPLYIGI 235

  Fly   245 STFLRMLGPAIGYSLAAVCLRLYIEPTLEPLIG----QEDPRWLGAWWLGWLVLAAITLVSAILL 305
            ...:..:||.:.|.|.::.||||::....|..|    .:||||:||||||:|:.:.:.::::...
Mouse   236 LFGITTMGPGLAYGLGSLMLRLYVDIDRMPEGGINLTPKDPRWVGAWWLGFLISSGLVVLASSPY 300

  Fly   306 FMFPKQLPSARK----RRLQLK---------QDERKQSLPLNERS-LADMMKTVKKLSKNKVYVY 356
            |.||:::|..:.    ||..|.         :|...|..||.::: ||.:...:..:...||:..
Mouse   301 FFFPREMPKEKHEFHFRRKVLASAASTASKGEDLSSQHEPLKKQAGLAQIAPDLTLVQFVKVFPR 365

  Fly   357 NTMASILYFFGYMVYW-------------IFTPKYIETQYRQSAAMATMATGTVALGFSAAGILI 408
            ..:.::.:....:|..             .|.||::|.|:..:|:.|.|..|.:.:.....||::
Mouse   366 VLLRNLRHPIFLLVVLSQVCTSSMVAGMATFLPKFLERQFSITASFANMLLGCLTIPLVIVGIMM 430

  Fly   409 SGYVISKYKPSARAMAAWNAIVDFVTVAGILCYV------AIGCEGSDRLNTLTTLSA--GNS-- 463
            .|.::.:...|....:|      ...:..:||.:      .|||...........|.|  |.|
Mouse   431 GGVLVKRLHLSPVQCSA------LCLLGSLLCLLFSVPLFFIGCSTHQIAGITQDLGAQPGPSLF 489

  Fly   464 --CSASCHCDYVHYAPVC-SADNITFISACHAGCSER-TKDALGRT--IYTGCECL-GSSSLNSE 521
              ||..|.|....:.||| ::..:.:.:.|||||:.| .::|||::  .||.|.|: |:.::.:
Mouse   490 PGCSEPCSCQSDDFNPVCDTSAYVEYTTPCHAGCTGRVVQEALGKSQVFYTNCSCVAGNGTVPA- 553

  Fly   522 PESQFAVDGTCPVDCFNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAAS 586
                    |:|...|....|.|:.:......:.:.:.:.:.:|.||.:..::||.|:|:..|...
Mouse   554 --------GSCESACSRLVLPFIVLFSLGAGLASITHTPSFMLILRGVKKEDKTLAVGMQFMLLR 610

  Fly   587 LLGFIPSPIFFGWLIDNYCLVWGKTCSNKGNCWLYDTKSMRYALNLSAAFFIFLGGFLNIAVWYH 651
            :|.::|||:..|..||..|:.|..||..:..|..||...:|             ..|:.:..::.
Mouse   611 VLAWMPSPVIHGSAIDTTCVHWALTCGRRAVCRYYDHDLLR-------------NRFIGLQFFFK 662

  Fly   652 AKNLKIF---------DEEESSPKDSLKNKEVE 675
            :.:|..|         ...|:|.:.::|:.|::
Mouse   663 SGSLVCFTLVLAILRQQSREASTRTTVKSSELQ 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	154/623 (25%)
		MFS	69..>425	CDD:119392	96/404 (24%)
		KAZAL_SLC21	462..514	CDD:238650	21/60 (35%)
Slco2b1	XP_011239939.1	MFS	54..591	CDD:391944	133/564 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835530
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750