Protein Alignment Oatp58Da and slco1f3

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001129156.2
• Gene: slco1f3 / 100190900
• ZFINID: ZDB-GENE-080212-5
• Length: 588
• Species: Danio rerio
• Alignment Length: 615
• Identity: 178/615 - (28%)
• Similarity: 291/615 - (47%)
• Gaps: 72/615 - (11%)

  Fly   109 VGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFL-----YGAGEDALQLTRE 168
            :||    :|...::.|.....|||:.:|.|:|.:....||.:|.||:     ||.   |...|.:
Zfish     1 MGN----ILVITLVSYVGAKFHRPKIIGAGVLLMGIGTLLMASPHFIMGRYRYGT---AATHTND 58

  Fly   169 FGQVNETLTNQERDKKLCQPTAGGCVQEEVG---LWVPQVFLFAAQLISGVGQALFYTLGIAYMD 230
            .|......|.....::..|....||.:||.|   ||   |.:.....:.|:|:|....||::::|
Zfish    59 DGNFTVISTCSSDSQETLQKPFSGCQKEESGRSPLW---VMVLLGNTMRGIGEASIVPLGMSFID 120

  Fly   231 DNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIE--------PTLEPLIGQEDPRWLGAW 287
            |......:...:.....|.::||..|:.|.::|..||::        .|:.|    :|.||:|||
Zfish   121 DYARPENSAFYIGCLNTLGVIGPIFGFMLGSLCANLYVDIDSVYQASVTITP----QDYRWVGAW 181

  Fly   288 WLGWLVLAAITLVSAILLFMFPKQLP-SARKRRLQLKQDERKQSLPLNERSLADMMKTVKKLSKN 351
            |||::|....||::|..|:.||:.|| :::...|...:.:.|.:..|.| .:.|...:.|.|..|
Zfish   182 WLGYVVSGLFTLLAAFPLWFFPRALPENSQISELNHPRQQHKTTPSLTE-IVKDFPPSFKHLLTN 245

  Fly   352 KVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKY 416
            |:|:.....||:.|..:.:...:||||:|.|:.|||:......|..::...|.||.:||.::.::
Zfish   246 KIYILYLAHSIVAFNDFAIGASYTPKYLEQQFGQSASKTNFLIGATSVPAVALGIFLSGLMMKRF 310

  Fly   417 K----PSARAMAAWNAIVDFVTVAGILCYVAIGCEGSDRLNTLTTLSAGN------------SCS 465
            |    .|||........:.|:.|.    :.|:.| |:..:..:|....|:            ||:
Zfish   311 KWDLLTSARVNLYAGVAMLFLAVP----FFALSC-GNLEVAGVTVPYQGSTEVQGVISDVLPSCN 370

  Fly   466 ASCHCDYVHYAPVCSADNITFISACHAGCSERTKDALGRTI-YTGCECLGSSSLNSEPESQFAVD 529
            |.|.|..:|:.|||..:.:|:||.|||||:...  ..||.: :..|.|:.|..|:....|  ||.
Zfish   371 ADCGCPDIHWDPVCGENGVTYISPCHAGCNSTL--GAGRNMTFHDCGCIQSWGLSVGNSS--AVL 431

  Fly   530 GTCPVD--CFNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIP 592
            |.|..|  |...|.|:||:......|.:........|:||.:.|:.|:.::|:......:||.||
Zfish   432 GQCSRDPKCNRMFYIYLGLQSLAFFVYSLGTVPYFTLSLRIVDPELKSISVGMLLFTVRVLGGIP 496

  Fly   593 SPIFFGWLIDNYCLVWGKTCS-NKGNCWLYDTKSMRYALNLSAAFFIFLGGFLNIAVW-YHAKNL 655
            :||:||.|||:.||.||:|.| .:|.|.:||.::.|         |:|.|..:.:.|. |....:
Zfish   497 APIYFGSLIDSTCLKWGRTKSCGRGACRIYDIETFR---------FLFQGLTIGLRVLAYSLLWI 552

  Fly   656 KIFDEEESSPKDSLKNKEVEMKTIDSN-PE 684
            ...:.:.....|...:::.|::...|| ||
Zfish   553 ATIEIQRKMKNDKQLSRDTELQKSPSNDPE 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	166/553 (30%)
		MFS	69..>425	CDD:119392	97/336 (29%)
		KAZAL_SLC21	462..514	CDD:238650	21/64 (33%)
slco1f3	NP_001129156.2	OATP	1..531	CDD:281175	166/553 (30%)
		MFS	<88..>339	CDD:119392	74/262 (28%)
		KAZAL_SLC21	366..418	CDD:238650	21/53 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D434101at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920