Protein Alignment Oatp58Da and slco2b1

DIOPT Version :9

• Sequence 1: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_031751477.1
• Gene: slco2b1 / 100125037
• XenbaseID: XB-GENE-6046634
• Length: 663
• Species: Xenopus tropicalis
• Alignment Length: 701
• Identity: 184/701 - (26%)
• Similarity: 327/701 - (46%)
• Gaps: 109/701 - (15%)

  Fly    32 SAPENETEGEDGGKDTYCGFWIFKGPSMQRFATEHMYVILYGLAGCVMTMTFAYFNGTITTLEKR 96
            ::.||::||.. .|.|.|         ...|....::|:.:|.......:...|...:|:|:|||
 Frog    12 TSAENKSEGLH-QKSTRC---------CHPFNNIKVFVLCHGFLQLSQLLLSGYLRSSISTIEKR 66

  Fly    97 YKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGED 161
            :.|.::.|||:|..|:|...:....:.|:....||||::|.|.:.:.|...|.|..||:.|
 Frog    67 FGISSQTSGILSSFNEIGNTVLIVFVSYFGSRVHRPRFIGCGAIIVCAAGFLMSLPHFIMG---- 127

  Fly   162 ALQLTREFGQVNETLTNQERDKKLCQPTA-------GGCVQ-----EEVGLWVPQVFLFAAQLIS 214
                ..|:.:...:|.:...|  :|||..       ..||:     .:..|::    ||..|::.
 Frog   128 ----PYEYDKSVASLLSNVTD--ICQPNGPIKSSDNDQCVEGVQKANKNVLFI----LFLGQILL 182

  Fly   215 GVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYI--------EPT 271
            |:|.......||:|:||..||..:|..:.:...:.::||.:.:.|.:..||.|:        |.|
 Frog   183 GIGSVPIQPFGISYIDDFASKRNSPLYIGILFAVTVMGPGVAFILGSAMLRFYVDIDKLSADEIT 247

  Fly   272 LEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKRRLQLKQDERKQSL----- 331
            |.|    :||||:||||||:||..::..:::|..|:||:::|   |:....|.:|.|.||
 Frog   248 LTP----KDPRWIGAWWLGYLVAGSVVAIASIPYFIFPREMP---KQGPSEKPEEPKPSLMDEIK 305

  Fly   332 ---PLNER-SLADMMKTVKKL----SKNKVYVYNTMASILYFFGYMVYWI-----FTPKYIETQY 383
               ..||: :|:..:|...|:    .||.|::...:|.     |.|...:     |..|::|.|:
 Frog   306 SKTEENEKLTLSQFIKVFPKVLFRTVKNPVFILIVLAQ-----GNMSAMVCGLATFMAKFLERQF 365

  Fly   384 RQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVAIGCE- 447
            ..:|::|.:..|:..:..:.:||::.|.::.:::.:.:..|....|...:.:...:..|.:||.
 Frog   366 SITASLANLLIGSANIPAAMSGIVLGGIIMKRHRLTPKQSALMCVIGLIICIFTAIPLVFLGCST 430

  Fly   448 ---GSDRLNTLTTLSAG-----NSCSASCHCDYVHYAPVCSADNITFISACHAGC-----SERTK 499
               .|.|::...  |:|     :.||..|.|....:.|||..|.:.:||.|:|||     .|...
 Frog   431 QQFASPRMDHQG--SSGIWQNVSECSGGCQCSSAAFNPVCGTDGVEYISPCYAGCGAVQFGESPT 493

  Fly   500 DALGRTIYTGCECLGSSSLNSEPESQFAVDGTCPVDCFNEFLIFLGVMCFLKLVGASSKSTNLLL 564
            :.|.   ||.|.|:        |.:..|..|:|...|....:.|:.:.|....:.:.:::.:.:|
 Frog   494 EVLN---YTRCTCI--------PAAGSAKPGSCGTVCGQLLVPFMVLSCLAGGLASMAQTPSFML 547

  Fly   565 ALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWGKTCSNKGNCWLYDTKSMRYA 629
            .||.:.|.:|:.|:|:..|...:|.::|.|:.:|.:||:.|::||:.|..|.:|..||...:|..
 Frog   548 ILRSVKPTDKSLAIGIQFMLLRILAWLPGPVMYGSVIDSTCILWGQKCGKKTSCQYYDNNLLRQR 612

  Fly   630 -LNLSAAFFIFLGGFLNI-AVWYHAKNLKIFDEEESSPKDSLKNKEVEMKT 678
             :.|...|.|  ||.:.. ||::..:.    .|:.|:.|...:|.|....|
 Frog   613 FIGLQILFEI--GGLIFFTAVFFVLRR----REKVSAEKSMRENPETHALT 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	162/610 (27%)
		MFS	69..>425	CDD:119392	104/393 (26%)
		KAZAL_SLC21	462..514	CDD:238650	20/56 (36%)
slco2b1	XP_031751477.1	MFS	35..550	CDD:421695	141/553 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010