DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ari-2 and ARI1

DIOPT Version :9

Sequence 1:	NP_477374.1	Gene:	ari-2 / 37542	FlyBaseID:	FBgn0025186	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_567966.1	Gene:	ARI1 / 829587	AraportID:	AT4G34370	Length:	597	Species:	Arabidopsis thaliana

Alignment Length:	505	Identity:	162/505 - (32%)
Similarity:	242/505 - (47%)	Gaps:	94/505 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DDY-------DYYNT---------GEDCDVERLDPKRADPEYFEYECLTVEDIEKLLNERVEKLN 67
            |||       .||::         .|:.:::.|..||::.:....|.|.....|.||  ||.:|
plant     2 DDYFSAEEEACYYSSDQDSLDGIDNEESELQPLSSKRSNTQVITQESLLAAQREDLL--RVMEL- 63

  Fly    68 TILQITPSLAKVLLLEHQWNNVAVVEK-----YRQDANALLVTARIKPPSVAVTDTASTSAAAAS 127
              |.|....|:.||:.:||:    |||     ..:..::|...|     .|.|.|
plant    64 --LSIKEHHARTLLIHYQWD----VEKLFAVFVEKGKDSLFSGA-----GVTVFD---------- 107

  Fly   128 AQLLRLGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDCWTIYFETQIFQGIS 192
                      |:...|:.||.....|.||.....||....:.|||.||.:|||.:|..||.:|.|
plant   108 ----------YQYGNSSFPQSSQMSCDVCMEDLPGDHMTRMDCGHCFCNNCWTEHFTVQINEGQS 162

  Fly   193 TQIGCMAQMCNVRVPEDLVLTLVT--RPVMRDKYQQFAFKDYVKSHPELRFCPG-PNCQIIVQSS 254
            .:|.|||..||....||:|.:||:  ||.:..|:.::..:.|::.:..:::||. |:|...:::.
plant   163 KRIRCMAHQCNAICDEDIVRSLVSKKRPDLAAKFDRYLLESYIEDNRMVKWCPSTPHCGNAIRAE 227

  Fly   255 EISAKRAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIE 319
            :.......| :|...|||.|....|:|..|.:.:.|..||.|:|||.|:|:.|||.||||:..:|
plant   228 DDKLCEVEC-SCGLQFCFSCLCQAHSPCSCLMWELWRKKCRDESETINWITVHTKLCPKCYKPVE 291

  Fly   320 KNGGCNHMQCFNCKHDFCWMCLGDWKTHGSEY-------YECSRYKDNPNIANESVHVQAREALK 377
            ||||||.::|. |...|||:|.|   ..||::       :.|.||:|:    .|....:|:..|.
plant   292 KNGGCNLVRCI-CGQCFCWLCGG---ATGSDHTYRSIAGHSCGRYQDD----KEKQMERAKRDLN 348

  Fly   378 KYLHYYERWENHSKSLKLEQQTIDRLRQRINSKVMNGSGTWI---DWQYLFNAAALLAKCRYTLQ 439
            :|.||:.|::.|:.|.|||    |:||..|:.||.......:   |:.::.|....|.:.|..|.
plant   349 RYTHYHHRYKAHTDSSKLE----DKLRDTIHEKVSKSEKRELKLKDFSWVTNGLDRLFRSRRVLS 409

  Fly   440 YTYPYAYYM-------------EAGSRKNLFEYQQAQLEAEIENLSWKIE 476
            |:|.:||||             |...:|||||.||.|||:.:|.||..:|
plant   410 YSYAFAYYMFGEEMFKDEMTPEEREIKKNLFEDQQQQLESNVEKLSQFLE 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	151..204	CDD:319687	23/52 (44%)
ari-2	NP_477374.1	IBR	222..284	CDD:214763	14/62 (23%)
ARI1	NP_567966.1	IBR	194..256	CDD:214763	14/62 (23%)
ARI1	NP_567966.1	IBR	<284..313	CDD:279784	16/29 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I3020
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I974
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1176
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11685
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X447
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	9.030