DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ari-2 and ARI4

DIOPT Version :9

Sequence 1:	NP_477374.1	Gene:	ari-2 / 37542	FlyBaseID:	FBgn0025186	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_189409.1	Gene:	ARI4 / 822394	AraportID:	AT3G27720	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	131/521 - (25%)
Similarity:	211/521 - (40%)	Gaps:	120/521 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DSDIEMDMESDN--DGEYDDDYDYYNTGEDCDVERLDPKRADPEYFEYECLTVEDIEKLLNERVE 64
            |..:.::.|.||  ..|:||.....:..|:.|::.                        ..|...
plant     3 DEYMSLEEEEDNCYPSEFDDHDQMCSNAEESDLQH------------------------SREPTS 43

  Fly    65 KLNTILQITPSLAKVLLLEHQWNNVAVVEKYRQDANALLVTARIKPPSVAVTDTASTSAAAASAQ 129
            ::...|.:|.:.|:.||:::|||...:...|......:|.       |.|..:...........:
plant    44 QVMEFLSVTENQARTLLIQYQWNVDKLFSVYTDQGKDVLF-------SRAEEEEGEDKEEEEGGE 101

  Fly   130 LLRLGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDCWTIYFETQIFQGISTQ 194
            .......|....|....:.......|....:..|:           ||     .|.|:   :||:
plant   102 DEEEEEGGEDEEAEEGGEDEEAEEGVEDEEEEEDE-----------KD-----DEVQL---VSTE 147

  Fly   195 IGCMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPG-PNCQIIVQS--SEI 256
            :.                         :|:.:|..:.||:.:..:::||. |:|...:::  .:.
plant   148 LA-------------------------EKFDRFLIESYVEDNNMVKWCPSTPHCGNAIRNIKDDG 187

  Fly   257 SAKRAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIEKN 321
            ......| :|...|||.|..:.|:|..|.:.|.|..||.|:|||.|:::.:||.||||...|:|.
plant   188 DVDEVEC-SCGLQFCFSCLSESHSPCSCLMWKLWKKKCEDESETVNWMTVNTKLCPKCSKPIQKR 251

  Fly   322 GGCNHMQCFNCKHDFCWMCLGDWKTHGSEY-----YECSRYKDNPNIANESVH--VQAREALKKY 379
            .|||||.| .|...|||:| |........|     :.|.|||:      |.|.  .:|:..|.:|
plant   252 DGCNHMTC-KCGQHFCWLC-GQATGRDHSYSSIAGHSCGRYKE------EKVRQLERAQRDLDRY 308

  Fly   380 LHYYERWENHSKSLKLEQQTIDRLRQRINSKVMNGSGT-----WIDWQYLFNAAALLAKCRYTLQ 439
            .||:.|::.|..|||||    |:|::.|..|.:..|.|     :.::.::.:|...|.:.|..|.
plant   309 THYHYRYKAHIDSLKLE----DKLKKSILKKAVLNSETKDQKVFKEYSWIIDAVNRLFRSRRILS 369

  Fly   440 YTYPYAYYM-------------EAGSRKNLFEYQQAQLEAEIENLSWKIERAETTDLGDLENQMD 491
            |:||:.:||             |...:|||||.||.|||..:|.||..:|  |..|..|.|..::
plant   370 YSYPFVFYMFGKELFKDDMSDEERNIKKNLFEDQQQQLEGNVERLSKILE--EPFDEYDHEKVVE 432

  Fly   492 I 492
            :
plant   433 M 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	151..204	CDD:319687	8/52 (15%)
ari-2	NP_477374.1	IBR	222..284	CDD:214763	16/64 (25%)
ARI4	NP_189409.1	IBR	150..214	CDD:214763	16/64 (25%)
		IBR	<237..271	CDD:366672	19/35 (54%)
		COG4026	<391..479	CDD:226513	19/45 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I3020
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I974
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1176
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11685
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X447
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	10.030