Protein Alignment ari-2 and rnf216

DIOPT Version :10

• Sequence 1: NP_477374.1
• Gene: ari-2 / 37542
• FlyBaseID: FBgn0025186
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_687871.3
• Gene: rnf216 / 559441
• ZFINID: ZDB-GENE-081104-199
• Length: 834
• Species: Danio rerio
• Alignment Length: 474
• Identity: 89/474 - (18%)
• Similarity: 145/474 - (30%)
• Gaps: 143/474 - (30%)

  Fly     8 DMESDNDGEYDDDYDYYNTGEDCDVERLDPKRADPEYFEYECLTVEDIEKLLNERVEKLNTILQI 72
            |.|:.....|.|.:.....|.:..|:..|....|     :..|:.:||:..||    .|.....|
Zfish   322 DSETQESENYFDYFKLKTVGPEVVVQAADMLMGD-----FRMLSCQDIKWALN----CLKGHYAI 377

  Fly    73 TPSLAKVLLLEHQWNNVAVVEKYRQDANALLVTARIKPPSVAVTDTASTSAAAASAQLL------ 131
            |.......|.:.|.|:.....|.::         |.:|...|..|......:....:.:
Zfish   378 TRKALFEALKKWQENSTDPSGKKKR---------RREPNERAYIDFKFEQGSFKLERKMYFLEKN 433

  Fly   132 RLGSSGYKTTASAT-----------------------------PQYRSQ----MCPVCASSQLGD 163
            |..|.|.:||..|:                             .||:..    .|..|......:
Zfish   434 RRWSRGNETTLEASLVKELQFYEQKAKEMAEHEDFLLALQVNEEQYQKDGQLIECGCCCGEFAFE 498

  Fly   164 KFYSLACGHSFCKDCWTIYFETQIFQGISTQIGCMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFA 228
            :......||.|||:|...|.:..:|....:::.||...|....|...:..::...::...|::.|
Zfish   499 EMTQCTDGHLFCKECLVKYAQEAVFGSGRSELSCMDGNCTCSFPNSELEKVLPENILCKYYERQA 563

  Fly   229 -------------------FKDYVKSHPELRFCPGPNCQIIVQSSEISAKRAICKACHTGFCFRC 274
                               |...:.....|..||.|.|           ::..|:.||..:
Zfish   564 EEAVAATCADELVRCPFCNFPALLDKDVSLFSCPNPRC-----------RKESCRKCHVVW---- 613

  Fly   275 GMDYHAPTDC-QVIKK---WLTKCADDSETANYISAHTKDCPKCHICIEKNGGCNHMQCFNCKHD 335
              ..||...| ||:::   .|....::..||    |..:.|.||...:.|:.|||.|.| .|...
Zfish   614 --KEHAGKTCEQVLERDEIRLRVAFEEKMTA----ARVRKCHKCATGLVKSEGCNRMWC-RCGAY 671

  Fly   336 FCWMCLGDWKTHGSEYYECSRYKDNPNIANESVHVQAREALKKYLHYYERWEN------HSKSLK 394
            .|::|                                ||.:..|.|:.:...:      |.|...
Zfish   672 MCYLC--------------------------------REPINGYNHFCQHARSPGAPCRHCKKCS 704

  Fly   395 L---EQQTIDRLRQRINSK 410
            |   ..|..:|:.|.|..:
Zfish   705 LWTDPTQDDERIIQEIQKE 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	152..204	CDD:438429	13/51 (25%)
		BRcat_RBR_TRIAD1	231..302	CDD:439005	15/74 (20%)
		Rcat_RBR_TRIAD1	306..361	CDD:439021	13/54 (24%)
		Ariadne	371..>477	CDD:466073	11/49 (22%)
rnf216	XP_687871.3	RING-HC_RBR_RNF216	486..542	CDD:438292	13/55 (24%)
		BRcat_RBR_RNF216	573..624	CDD:439000	12/67 (18%)
		Rcat_RBR_RNF216	637..693	CDD:439014	19/92 (21%)