DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ari-2 and rnf19a

DIOPT Version :9

Sequence 1:	NP_477374.1	Gene:	ari-2 / 37542	FlyBaseID:	FBgn0025186	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001313624.1	Gene:	rnf19a / 557995	ZFINID:	ZDB-GENE-030131-9414	Length:	913	Species:	Danio rerio

Alignment Length:	278	Identity:	68/278 - (24%)
Similarity:	120/278 - (43%)	Gaps:	52/278 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 NNVAVVEK------YRQDANALLVTARIKPPSVAVTDTASTSAAAASAQLLRLGSSGYKTTASAT 145
            :.:|.||.      .:||..:.|..|     .||.|.::.:|::.::::||.
Zfish   152 DGIASVESVHSEMCQQQDHASALSAA-----GVAYTSSSCSSSSGSTSELLE------------- 198

  Fly   146 PQYRSQMCPVCASSQLGDKFYS-LACGHSFCKDCWTIYFETQIFQGISTQIGCMAQMCNVRV-PE 208
                   ||:|......|:|.. :.|.|..|.||...|...:|.:   :::......|:.|. |.
Zfish   199 -------CPLCLLRHTRDRFPDIMTCHHRSCADCLRQYLRIEISE---SRVNISCPECSERFNPH 253

  Fly   209 DLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNC-QIIVQSSEISAKRAIC--KACHTGF 270
            |:.:.|..| |:.:||::|..:.::.:.|:.|:||.|:| ..::.....|..:..|  ..|.|.|
Zfish   254 DIRMILNDR-VLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKITCGRDGCGTEF 317

  Fly   271 CFRCGMDYHAPTDCQV----------IKKWLTKCADDSETANYISAHTKDCPKCHICIEK--NGG 323
            |:.|...:|....|..          ::.:.:.....|:.:...:...|.||:|...|.|  :|.
Zfish   318 CYHCKQLWHPNQTCDAARQQRAQSLRLRPFRSSSLSYSQESGAAADDIKPCPRCAAYIIKMNDGS 382

  Fly   324 CNHMQCFNCKHDFCWMCL 341
            ||||.|..|..:|||:|:
Zfish   383 CNHMTCAVCGCEFCWLCM 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	151..204	CDD:319687	13/53 (25%)
ari-2	NP_477374.1	IBR	222..284	CDD:214763	17/64 (27%)
rnf19a	NP_001313624.1	IBR	266..331	CDD:214763	17/64 (27%)
		IBR	<364..402	CDD:279784	17/37 (46%)
		AzlC	<428..517	CDD:294385
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910