Protein Alignment ari-2 and arih2

DIOPT Version :10

• Sequence 1: NP_477374.1
• Gene: ari-2 / 37542
• FlyBaseID: FBgn0025186
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_998308.1
• Gene: arih2 / 406417
• ZFINID: ZDB-GENE-040426-2158
• Length: 492
• Species: Danio rerio
• Alignment Length: 511
• Identity: 277/511 - (54%)
• Similarity: 352/511 - (68%)
• Gaps: 40/511 - (7%)

  Fly     2 DSDIEMDMESDNDGEYDDDYDYYNTGEDCDVERLDPKRADPEYFEYECLTVEDIEKLLNERVEKL 66
            ||:.|.:.:.::.||.|..:.|.|..||..||  :|  .|||.:::.|||..:.:::|.|:|..:
Zfish    11 DSNEEFEDDDEDIGEGDIPHYYDNLEEDVAVE--EP--FDPEKYQFNCLTYRESQRVLTEQVNNV 71

  Fly    67 NTILQITPSLAKVLLLEHQWNNVAVVEKYRQDANALLVTARIKPPSVAVTDTASTSAAAASAQLL 131
            .:.|:::|::||::|:...|..|.::|:|:.:::.||..|..:|.:...:.||.||.
Zfish    72 ASALKVSPAVAKLVLVHFHWQVVQILERYKSNSSQLLCEAYAQPTTTCRSLTAGTSL-------- 128

  Fly   132 RLGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDCWTIYFETQIFQGISTQIG 196
                                .|.||......|...||.|.|||||.||..:....:..|:..:|.
Zfish   129 --------------------QCGVCLQLVRRDALLSLPCQHSFCKGCWEQHCTVLVKDGVGVEIS 173

  Fly   197 CMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQIIVQSSEISAKRA 261
            ||||.|::|:|||.||.|:....::|||:::.|:|||:||.:|:.|||.:|.|::|..|..|:|.
Zfish   174 CMAQDCSLRMPEDFVLPLLPSEELKDKYRRYLFRDYVESHFQLQLCPGADCPIVIQVQEPRARRV 238

  Fly   262 ICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIEKNGGCNH 326
            .|..|...|||:|...|||||||..|:||||||||||||||||||||||||||:|||||||||||
Zfish   239 QCSRCEEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNH 303

  Fly   327 MQCFNCKHDFCWMCLGDWKTHGSEYYECSRYKDNPNIANESVHVQAREALKKYLHYYERWENHSK 391
            |||..|||||||||||||||||||||||||||:||:|.|:|...||||||||||.|:||||||:|
Zfish   304 MQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNK 368

  Fly   392 SLKLEQQTIDRLRQRINSKVMNGSGTWIDWQYLFNAAALLAKCRYTLQYTYPYAYYMEAGSRKNL 456
            ||:||.||..|::::|..:|||..|||||||||.|||.||||||||||||||||||||:|.||.|
Zfish   369 SLQLEAQTYQRIQEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKL 433

  Fly   457 FEYQQAQLEAEIENLSWKIERAET--------TDLGDLENQMDIAEKRRTTLLKDF 504
            ||||||||||||||||||:|||:|        .|.|||||||.|||::|.||||||
Zfish   434 FEYQQAQLEAEIENLSWKVERADTYERGEPSANDRGDLENQMHIAEQKRRTLLKDF 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	152..204	CDD:438429	21/51 (41%)
		BRcat_RBR_TRIAD1	231..302	CDD:439005	41/70 (59%)
		Rcat_RBR_TRIAD1	306..361	CDD:439021	50/54 (93%)
		Ariadne	371..>477	CDD:466073	83/105 (79%)
arih2	NP_998308.1	RING-HC_RBR_TRIAD1	129..181	CDD:438429	21/51 (41%)
		BRcat_RBR_TRIAD1	208..279	CDD:439005	41/70 (59%)
		Rcat_RBR_TRIAD1	283..338	CDD:439021	50/54 (93%)
		Ariadne	343..>449	CDD:466073	80/105 (76%)