DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ari-2 and Rnf19a

DIOPT Version :9

Sequence 1:	NP_477374.1	Gene:	ari-2 / 37542	FlyBaseID:	FBgn0025186	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	XP_038935442.1	Gene:	Rnf19a / 362900	RGDID:	1307807	Length:	861	Species:	Rattus norvegicus

Alignment Length:	215	Identity:	56/215 - (26%)
Similarity:	93/215 - (43%)	Gaps:	39/215 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 CPVCASSQLGDKFYS-LACGHSFCKDCWTIYFETQIFQGISTQIGCMAQMCNVRV-PEDLVLTLV 215
            ||:|......|:|.. :.|.|..|.||...|...:|.:   :::......|..|. |.|:.| ::
  Rat   132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISE---SRVNISCPECTERFNPHDIRL-IL 192

  Fly   216 TRPVMRDKYQQFAFKDYVKSHPELRFCPGPNC-QIIVQSSEISAKRAIC--KACHTGFCFRCGMD 277
            :..|:.:||::|..:.::.:.|:.|:||.|:| ..::.....|..:..|  :.|.|.||:.|...
  Rat   193 SDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQI 257

  Fly   278 YHAPTDCQVIKKWLTKCADDSETANYISAHT-------------------KDCPKCHICIEK--N 321
            :|....|...::         |.|..:...|                   |.||:|...|.|  :
  Rat   258 WHPNQTCDAARQ---------ERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMND 313

  Fly   322 GGCNHMQCFNCKHDFCWMCL 341
            |.||||.|..|..:|||:|:
  Rat   314 GSCNHMTCAVCGCEFCWLCM 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	151..204	CDD:319687	13/51 (25%)
ari-2	NP_477374.1	IBR	222..284	CDD:214763	17/64 (27%)
Rnf19a	XP_038935442.1	RING-HC_RBR_RNF19A	131..185	CDD:319689	14/55 (25%)
		IBR	199..264	CDD:214763	17/64 (27%)
		IBR	<297..335	CDD:396187	17/37 (46%)
		AzlC	<361..450	CDD:412452
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910