Protein Alignment ari-2 and ari-1

DIOPT Version :10

• Sequence 1: NP_477374.1
• Gene: ari-2 / 37542
• FlyBaseID: FBgn0025186
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_523399.1
• Gene: ari-1 / 32796
• FlyBaseID: FBgn0017418
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 176/513 - (34%)
• Similarity: 279/513 - (54%)
• Gaps: 44/513 - (8%)

  Fly     9 MESDNDGEYDDDYDYYNT----------GEDCDVERLDPKRADPEYFEYECLTVEDIEKLLNERV 63
            |:||||.::.|:.|..|.          |.:.|:.....::.|.:.::|:.||.::|.:...|.:
  Fly     1 MDSDNDNDFCDNVDSGNVSSGDDGDDDFGMEVDLPSSADRQMDQDDYQYKVLTTDEIVQHQREII 65

  Fly    64 EKLNTILQITPSLAKVLLLEHQWNNVAVVEKYRQD-ANALLVTARIKPPSVAVTDTASTSAAAAS 127
            ::.|.:|::.....::||...:|:...::|||..| .:.....|.:..|         .:|..|.
  Fly    66 DEANLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFKCAHVINP---------FNATEAI 121

  Fly   128 AQLLRLGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDCWTIYFETQIF-QGI 191
            .|         ||:.|     :.:.|.:|.|....|....|.|||.||..||..|..|:|. :|:
  Fly   122 KQ---------KTSRS-----QCEECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAEGL 172

  Fly   192 STQIGCMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQIIVQSSEI 256
            ...|.|.|..|::.|.:..|..|||...:|.||||.....:|:.:..||:||..:|...|:....
  Fly   173 GQTISCAAHGCDILVDDVTVANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPYA 237

  Fly   257 SAKRAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIEKN 321
            ..:|..||..|. |||.||.::|.|..|:.:|||:.||.|||||:|:|:|:||:||:|.:.|||:
  Fly   238 EPRRVHCKCGHV-FCFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKD 301

  Fly   322 GGCNHMQC--FNCKHDFCWMCLGDWKTHGSEYYECSRYKDNPNIANESVHVQAREALKKYLHYYE 384
            ||||||.|  .|||::|||:|||.|:.|||.:|.|:||.::..........:.|.:|.:|||||.
  Fly   302 GGCNHMVCKNQNCKNEFCWVCLGSWEPHGSSWYNCNRYDEDEAKTARDAQEKLRSSLARYLHYYN 366

  Fly   385 RWENHSKSLKLEQQTIDRLRQRINSKVMNGSGTWIDWQYLFNAAALLAKCRYTLQYTYPYAYYME 449
            |:.||.:|:|.|.:....::|:: .::...:.:||:.|:|..|..:|.:||.||.|||.:|||::
  Fly   367 RYMNHMQSMKFENKLYASVKQKM-EEMQQHNMSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYLK 430

  Fly   450 AGSRKNLFEYQQAQLEAEIENLSWKIERAETTD-LGDLENQMD----IAEKRRTTLLK 502
            ..::..:||..|..||:..|.||..:||..|:: |.|::.::.    ..|||.:.|||
  Fly   431 KNNQSMIFEDNQKDLESATEMLSEYLERDITSENLADIKQKVQDKYRYCEKRCSVLLK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	152..204	CDD:438429	20/52 (38%)
		BRcat_RBR_TRIAD1	231..302	CDD:439005	29/70 (41%)
		Rcat_RBR_TRIAD1	306..361	CDD:439021	33/56 (59%)
		Ariadne	371..>477	CDD:466073	38/105 (36%)
ari-1	NP_523399.1	RING-HC_RBR_HHARI	131..189	CDD:438288	21/57 (37%)
		BRcat_RBR_HHARI-like	198..279	CDD:439004	31/81 (38%)
		Rcat_RBR_HHARI-like	283..340	CDD:439017	33/56 (59%)
		Ariadne	341..>459	CDD:466073	39/118 (33%)