Protein Alignment ari-2 and ari-1.3

DIOPT Version :9

• Sequence 1: NP_477374.1
• Gene: ari-2 / 37542
• FlyBaseID: FBgn0025186
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001379539.1
• Gene: ari-1.3 / 172282
• WormBaseID: WBGene00016156
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 176/519 - (33%)
• Similarity: 277/519 - (53%)
• Gaps: 62/519 - (11%)

  Fly     1 MDSDIEMDMESDNDGEYDDDYDYYNTGEDCDVERLDPKRADPEYF-----EYECLTVEDIEKLLN 60
            |:||.|:.||.....|  ||.|.....:|..:.|.|...:|  |.     :.|.|..:.:|..:.
 Worm     1 MNSDDEIYMEGSASSE--DDMDDECLSDDDGIARHDQSASD--YLNKKDKDNEVLDHDSLEAEMK 61

  Fly    61 ERVEKLNTILQITPSLAKVLLLEHQWNNVAVVEKYRQ--DANALLVTARIKPPSVAVTDTASTSA 123
            :.:.::..:||:...:.::||.:::||..:::|::.:  |..|.|:.|::.|....|       .
 Worm    62 KAISEVEAVLQVKTGVCRILLHKYKWNKESLLERFYEHPDTIAFLIDAQVIPRQQEV-------I 119

  Fly   124 AAASAQLLRLGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDCWTIYFETQIF 188
            .|..|:                       |.:|.|.   |:...|:|.|..|.:||..|...:|.
 Worm   120 PAGDAE-----------------------CDICCSM---DELSGLSCNHRACAECWQAYLTNKIV 158

  Fly   189 QGISTQIGCMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQIIVQS 253
            ....::|.|||..|.:.:.::.||:.::.|.|..||::.....||:.:..||:|||.:|...|:.
 Worm   159 SDAQSEIECMAPNCKLLIEDEKVLSYISDPTMVSKYRKLMVASYVEINCLLRWCPGIDCGKAVKV 223

  Fly   254 SEISAKRAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICI 318
            |....:..:| :|.|.|||.||.::|.|.:|:.:|||:.||.|||||.|:|:|:|||||||.|.|
 Worm   224 SHWEPRLVVC-SCGTCFCFSCGQNWHEPLNCRHLKKWIKKCQDDSETMNWINANTKDCPKCMIPI 287

  Fly   319 EKNGGCNHMQCFN--CKHDFCWMCLGDWKTHGSEYYECSRYKD----NPNIANESVHVQAREALK 377
            |||||||.|.|.|  |:::||||||..|..||.: |.|:.|.:    ||..|.|.    :|..||
 Worm   288 EKNGGCNRMLCTNSGCRYEFCWMCLEPWTKHGYQ-YACNGYDETAVKNPQDAQEI----SRANLK 347

  Fly   378 KYLHYYERWENHSKSLKLEQQTIDRLRQRINSKVMNGSGTWIDWQYLFNAAALLAKCRYTLQYTY 442
            :||.|:.|:..|.:||:||.:...::.::: .::.|.|.:||:.|:|..|..:|::||.||.|||
 Worm   348 RYLFYFNRYMGHEQSLQLEGKLNIKVAKKM-EQMENMSMSWIEVQFLRKAVDILSECRRTLMYTY 411

  Fly   443 PYAYYMEAGSRKNLFEYQQAQLEAEIENLSWKIER-AETTDLGDLENQMD----IAEKRRTTLL 501
            .:|:|::..:...:||..||.||.|.|.||..:|| .|..||..|:.::.    ..|:||..||
 Worm   412 AFAFYLKKDNNSIIFESNQANLEMETEQLSGFLERDLEDEDLVTLKQKVQDKYRYVEQRRKVLL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	151..204	CDD:319687	17/52 (33%)
		IBR	222..284	CDD:214763	22/61 (36%)
ari-1.3	NP_001379539.1	RING_Ubox	125..178	CDD:418438	17/78 (22%)
		RING-HC finger (C3HC4-type)	126..172	CDD:319361	16/48 (33%)
		IBR	193..253	CDD:214763	22/60 (37%)
		IBR	<274..315	CDD:396187	27/40 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54219
OrthoDB	1	1.010	-	-		D429758at33208
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X447
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930