Protein Alignment Alp8 and Alpi

DIOPT Version :9

• Sequence 1: NP_001286709.1
• Gene: Alp8 / 37540
• FlyBaseID: FBgn0034712
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001074551.1
• Gene: Alpi / 76768
• MGIID: 1924018
• Length: 554
• Species: Mus musculus
• Alignment Length: 480
• Identity: 195/480 - (40%)
• Similarity: 281/480 - (58%)
• Gaps: 25/480 - (5%)

  Fly    56 PPEEMDPQYWYNIADEEITKRLQLPQPNSQKAKNIIMFLGDGMPLSTVAAARILKGQRQGNTGEE 120
            |.||.:|.:|...|.|.:....:| ||....|||:|:||||||.:.||.|.||||||.:|:.|.|
Mouse    23 PAEEENPAFWNKKAAEALDAAKKL-QPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPE 86

  Fly   121 SSLSFERFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVNIGVSAAVEYNNCTASQDPANRL 185
            :.|:.:.|||..||:||..:.||||||.||||||||||.|...||:|||...:.|..:.  .|.:
Mouse    87 TPLAMDLFPYMALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGLSAAARLDQCNTTF--GNEV 149

  Fly   186 TSIAEWAQNAGKSTGIVTTTTLTHASPSGAYAKTANRMWECDTDVTSYGVDANSCIDMATQLVTQ 250
            .|:...|:.||||.|:||||.:.||||:|.||.|.||.|..|.::.:..:. :.|.|:||||::
Mouse   150 FSVMYRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDAEMPASALQ-DGCKDIATQLIS- 212

  Fly   251 TPGKNFEVMFGGGMGKFLPNSIVD----SHGN-PGERSDGVNLLSRWQGLHDGGVLVTNRNQLLK 310
              ..:.:|:.|||.....|....|    |..| .|.|.|..||:..|...|.|...|.||::|::
Mouse   213 --NMDIDVILGGGRKFMFPKGTPDPEYPSDSNQSGTRLDDQNLVQTWLSKHQGARYVWNRSELIQ 275

  Fly   311 LNVS-AVSSVIGLFQSKLMNFHLEADDTYQPTLSELTEVTIKKLSQNKEHGYFAFIEGGLIDYGN 374
            .:.. ||:.::|||:...|.:....:.:..|:|:|:|||.::.||:|.: |::.|:|||.||.|:
Mouse   276 ASQDPAVTHLMGLFEPTEMKYDANRNPSVDPSLAEMTEVAVRMLSRNPQ-GFYLFVEGGRIDQGH 339

  Fly   375 HYTKAGYALDEALEFEKAIQLARDMTDIEDTLIVVTADHGHAVSIAGYPGRGTPILGINQHDTDI 439
            |...|..||.||:.|:.||:.|..:|:.:||||::||||.|..:..||..|||.|.|:..... :
Mouse   340 HAGTAYLALTEAVMFDSAIEKASQLTNEKDTLILITADHSHVFAFGGYTLRGTSIFGLAPLKA-L 403

  Fly   440 NGVQYSVLNYAAGPNQYLDENGQRIPLDDILGSDDAITPSY-----IPKDQGVHSGEDVGIFASG 499
            :...|:.:.|..||...| ::|.|..:.:.    .::.|:|     :|.....|.||||.|||.|
Mouse   404 DDKSYTSILYGNGPGYEL-KSGNRPNVTEA----QSVDPNYKQQAAVPLSSETHGGEDVAIFARG 463

  Fly   500 PQSHLFTGVMQQSTIPHLMAYAACI 524
            ||:||..||.:|:.|.|:||:|.|:
Mouse   464 PQAHLVHGVQEQNYIAHVMAFAGCL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp8	NP_001286709.1	ALP_like	88..525	CDD:304875	184/448 (41%)
Alpi	NP_001074551.1	Alk_phosphatase	53..488	CDD:278666	184/447 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847903
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm8903
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.760